A mutant allele of BARA/LIN-9 rescues the cdk4-/- phenotype by releasing the repression on E2F-regulated genes.

A mutant allele of BARA/LIN-9 rescues the cdk4-/- phenotype by releasing the repression on E2F-regulated genes.

Item
http://www.wikidata.org/entity/Q34531284
ARF-induced downregulation of Mip130/LIN-9 protein levels mediates a positive feedback that leads to increased expression of p16Ink4a and p19Arf.The DREAM complex: master coordinator of cell cycle-dependent gene expression.Mip/LIN-9 regulates the expression of B-Myb and the induction of cyclin A, cyclin B, and CDK1.The SynMuv genes of Caenorhabditis elegans in vulval development and beyondMip/LIN-9 can inhibit cell proliferation independent of the pocket proteins.lin9 is required for mitosis and cell survival during early zebrafish development.Deletion of the p107/p130-binding domain of Mip130/LIN-9 bypasses the requirement for CDK4 activity for the dissociation of Mip130/LIN-9 from p107/p130-E2F4 complexLIN-9 phosphorylation on threonine-96 is required for transcriptional activation of LIN-9 target genes and promotes cell cycle progression.Lin9, a subunit of the mammalian DREAM complex, is essential for embryonic development, for survival of adult mice, and for tumor suppression.The Schistosoma mansoni genome encodes thousands of long non-coding RNAs predicted to be functional at different parasite life-cycle stages.
P2860

A mutant allele of BARA/LIN-9 rescues the cdk4-/- phenotype by releasing the repression on E2F-regulated genes.

Item
http://www.wikidata.org/entity/Q34531284
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2006 nî lūn-bûn
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2006 թուականի Ապրիլին հրատարակուած գիտական յօդուած
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2006 թվականի ապրիլին հրատարակված գիտական հոդված
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2006年の論文
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2006年論文
@yue
2006年論文
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2006年論文
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2006年論文
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2006年論文
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2006年论文
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name
A mutant allele of BARA/LIN-9 ...... ession on E2F-regulated genes.
@ast
A mutant allele of BARA/LIN-9 ...... ession on E2F-regulated genes.
@en
A mutant allele of BARA/LIN-9 ...... ession on E2F-regulated genes.
@nl
type
label
A mutant allele of BARA/LIN-9 ...... ession on E2F-regulated genes.
@ast
A mutant allele of BARA/LIN-9 ...... ession on E2F-regulated genes.
@en
A mutant allele of BARA/LIN-9 ...... ession on E2F-regulated genes.
@nl
prefLabel
A mutant allele of BARA/LIN-9 ...... ession on E2F-regulated genes.
@ast
A mutant allele of BARA/LIN-9 ...... ession on E2F-regulated genes.
@en
A mutant allele of BARA/LIN-9 ...... ession on E2F-regulated genes.
@nl
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P31
P356
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P478
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P5875
P698
P356
P1433
P1476
A mutant allele of BARA/LIN-9 ...... ression on E2F-regulated genes
@en
P2093
P304
P31
P356
10.1016/J.YEXCR.2006.04.002
P407
P433
P478
P50
P577
P5875
P698