Pterin transport and metabolism in Leishmania and related trypanosomatid parasites.
about
Development and validation of a cytochrome c-coupled assay for pteridine reductase 1 and dihydrofolate reductaseUnresponsiveness to Glucantime treatment in Iranian cutaneous leishmaniasis due to drug-resistant Leishmania tropica parasites.Formation of linear amplicons with inverted duplications in Leishmania requires the MRE11 nucleaseHeme pathway evolution in kinetoplastid protistsPhylogeny as a guide to structure and function of membrane transport proteins.Identification of transport-critical residues in a folate transporter from the folate-biopterin transporter (FBT) family.Functional identification of orthologous genes encoding pterin recycling activity in Plasmodium falciparum and Toxoplasma gondiiTrypanosoma brucei pteridine reductase 1 is essential for survival in vitro and for virulence in micePhenylalanine hydroxylase (PAH) from the lower eukaryote Leishmania major.Gene amplification and point mutations in pyrimidine metabolic genes in 5-fluorouracil resistant Leishmania infantum.Development of Vaccines against Visceral LeishmaniasisGenome evolution in trypanosomatid parasites.Chromosomal Translocations in the Parasite Leishmania by a MRE11/RAD50-Independent Microhomology-Mediated End Joining MechanismKinetoplastids: related protozoan pathogens, different diseases.Genomic Appraisal of the Multifactorial Basis for In Vitro Acquisition of Miltefosine Resistance in Leishmania donovaniMethylene tetrahydrofolate dehydrogenase/cyclohydrolase and the synthesis of 10-CHO-THF are essential in Leishmania major.Folate metabolic pathways in LeishmaniaTolerance to drug-induced cell death favours the acquisition of multidrug resistance in Leishmania.Detection of cancer cells using a peptide nanotube-folic acid modified graphene electrode.Phosphoproteomic analysis of wild-type and antimony-resistant Leishmania braziliensis lines by 2D-DIGE technology.PTR1-dependent synthesis of tetrahydrobiopterin contributes to oxidant susceptibility in the trypanosomatid protozoan parasite Leishmania major.Chemical and genetic validation of dihydrofolate reductase-thymidylate synthase as a drug target in African trypanosomes.Modulation of gene expression in drug resistant Leishmania is associated with gene amplification, gene deletion and chromosome aneuploidy.Gene regulation of pteridine reductase 1 in leishmania promastigotes and amastigotes using a full-length antisense construct.A new type of high affinity folic acid transporter in the protozoan parasite Leishmania and deletion of its gene in methotrexate-resistant cells.Proteome mapping of the protozoan parasite Leishmania and application to the study of drug targets and resistance mechanisms.Inactivation of the Leishmania tarentolae pterin transporter (BT1) and reductase (PTR1) genes leads to viable parasites with changes in folate metabolism and hypersensitivity to the antifolate methotrexate.Leishmania (Viannia) braziliensis growth in vitro culture relies more on folic acid availability than Leihsmania (Leishmania) amazonensis.Higher plant plastids and cyanobacteria have folate carriers related to those of trypanosomatids.In Silico Identification and In Vitro Evaluation of Natural Inhibitors of Leishmania major Pteridine Reductase I.Genome wide comparison of Ethiopian Leishmania donovani strains reveals differences potentially related to parasite survival.
P2860
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P2860
Pterin transport and metabolism in Leishmania and related trypanosomatid parasites.
description
2002 nî lūn-bûn
@nan
2002 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Pterin transport and metabolism in Leishmania and related trypanosomatid parasites.
@ast
Pterin transport and metabolism in Leishmania and related trypanosomatid parasites.
@en
Pterin transport and metabolism in Leishmania and related trypanosomatid parasites.
@nl
type
label
Pterin transport and metabolism in Leishmania and related trypanosomatid parasites.
@ast
Pterin transport and metabolism in Leishmania and related trypanosomatid parasites.
@en
Pterin transport and metabolism in Leishmania and related trypanosomatid parasites.
@nl
prefLabel
Pterin transport and metabolism in Leishmania and related trypanosomatid parasites.
@ast
Pterin transport and metabolism in Leishmania and related trypanosomatid parasites.
@en
Pterin transport and metabolism in Leishmania and related trypanosomatid parasites.
@nl
P2093
P1476
Pterin transport and metabolism in Leishmania and related trypanosomatid parasites.
@en
P2093
Amal El-Fadili
Christoph Kündig
Dave Richard
Gaétan Roy
Jolyne Drummelsmith
Marc Ouellette
P304
P356
10.1016/S0020-7519(01)00346-0
P577
2002-04-01T00:00:00Z