INF2 Is a WASP homology 2 motif-containing formin that severs actin filaments and accelerates both polymerization and depolymerization.
about
Mutations in the formin gene INF2 cause focal segmental glomerulosclerosisAn actin-dependent step in mitochondrial fission mediated by the ER-associated formin INF2Formins and microtubulesFormins at a glanceSpire and Formin 2 synergize and antagonize in regulating actin assembly in meiosis by a ping-pong mechanismStructure of the formin-interaction domain of the actin nucleation-promoting factor Bud6Rickettsia Sca2 has evolved formin-like activity through a different molecular mechanismRevisiting the Phylogeny of the Animal Formins: Two New Subtypes, Relationships with Multiple Wing Hairs Proteins, and a Lost Human ForminA nucleator arms race: cellular control of actin assemblyAn mDia1-INF2 formin activation cascade facilitated by IQGAP1 regulates stable microtubules in migrating cells.INF2 is an endoplasmic reticulum-associated formin protein.Characterization of the biochemical properties and biological function of the formin homology domains of Drosophila DAAM.The formin FRL1 (FMNL1) is an essential component of macrophage podosomes.INF2 promotes the formation of detyrosinated microtubules necessary for centrosome reorientation in T cellsThe role of formin tails in actin nucleation, processive elongation, and filament bundling.Calcium-mediated actin reset (CaAR) mediates acute cell adaptationsThrombotic Microangiopathy in Inverted Formin 2-Mediated Renal Disease.Proteomic changes resulting from gene copy number variations in cancer cellsFormins in development: orchestrating body plan origami.The effects of formins on the conformation of subdomain 1 in actin filaments.Nanostructured self-assembly of inverted formin 2 (INF2) and F-actin-INF2 complexes revealed by atomic force microscopySplice variant-specific cellular function of the formin INF2 in maintenance of Golgi architecture.The C terminus of formin FMNL3 accelerates actin polymerization and contains a WH2 domain-like sequence that binds both monomers and filament barbed endsINF2-mediated severing through actin filament encirclement and disruption.Novel roles for actin in mitochondrial fissionThe ability to induce microtubule acetylation is a general feature of formin proteins.Inverted formin 2 in focal adhesions promotes dorsal stress fiber and fibrillar adhesion formation to drive extracellular matrix assemblyRho activation of mDia formins is modulated by an interaction with inverted formin 2 (INF2)Genetic causes of proteinuria and nephrotic syndrome: impact on podocyte pathobiology.The formin DAD domain plays dual roles in autoinhibition and actin nucleation.Structure, function, and evolution of the beta-thymosin/WH2 (WASP-Homology2) actin-binding module.Dynamic remodeling of the actin cytoskeleton by FMNL1γ is required for structural maintenance of the Golgi complex.Differential interactions of the formins INF2, mDia1, and mDia2 with microtubules.Pharmacological targeting of actin-dependent dynamin oligomerization ameliorates chronic kidney disease in diverse animal models.Assembly and turnover of short actin filaments by the formin INF2 and profilinA mitochondria-anchored isoform of the actin-nucleating spire protein regulates mitochondrial division.Diagnosing FSGS without kidney biopsy - a novel INF2-mutation in a family with ESRD of unknown originAutoinhibition of the formin Cappuccino in the absence of canonical autoinhibitory domains.Mutations to the formin homology 2 domain of INF2 protein have unexpected effects on actin polymerization and severing.Simultaneous sequencing of 24 genes associated with steroid-resistant nephrotic syndrome.
P2860
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P2860
INF2 Is a WASP homology 2 motif-containing formin that severs actin filaments and accelerates both polymerization and depolymerization.
description
2006 nî lūn-bûn
@nan
2006 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
INF2 Is a WASP homology 2 moti ...... rization and depolymerization.
@ast
INF2 Is a WASP homology 2 moti ...... rization and depolymerization.
@en
INF2 Is a WASP homology 2 moti ...... rization and depolymerization.
@nl
type
label
INF2 Is a WASP homology 2 moti ...... rization and depolymerization.
@ast
INF2 Is a WASP homology 2 moti ...... rization and depolymerization.
@en
INF2 Is a WASP homology 2 moti ...... rization and depolymerization.
@nl
prefLabel
INF2 Is a WASP homology 2 moti ...... rization and depolymerization.
@ast
INF2 Is a WASP homology 2 moti ...... rization and depolymerization.
@en
INF2 Is a WASP homology 2 moti ...... rization and depolymerization.
@nl
P2860
P356
P1476
INF2 Is a WASP homology 2 moti ...... erization and depolymerization
@en
P2093
Ekta Seth Chhabra
P2860
P304
26754-26767
P356
10.1074/JBC.M604666200
P407
P577
2006-07-03T00:00:00Z