Rho activation of mDia formins is modulated by an interaction with inverted formin 2 (INF2)
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An mDia1-INF2 formin activation cascade facilitated by IQGAP1 regulates stable microtubules in migrating cells.INF2 promotes the formation of detyrosinated microtubules necessary for centrosome reorientation in T cellsExome sequencing and in vitro studies identified podocalyxin as a candidate gene for focal and segmental glomerulosclerosis.Splice variant-specific cellular function of the formin INF2 in maintenance of Golgi architecture.Inverted formin 2 in focal adhesions promotes dorsal stress fiber and fibrillar adhesion formation to drive extracellular matrix assemblyPathophysiology and treatment of focal segmental glomerulosclerosis: the role of animal models.Genetic causes of proteinuria and nephrotic syndrome: impact on podocyte pathobiology.The role of reactive oxygen species in microvascular remodeling.Differing and isoform-specific roles for the formin DIAPH3 in plasma membrane blebbing and filopodia formation.RhoA deficiency disrupts podocyte cytoskeleton and induces podocyte apoptosis by inhibiting YAP/dendrin signalMutations in the INF2 gene account for a significant proportion of familial but not sporadic focal and segmental glomerulosclerosisInverted formin 2 regulates actin dynamics by antagonizing Rho/diaphanous-related formin signaling.Inverted formin 2 mutations with variable expression in patients with sporadic and hereditary focal and segmental glomerulosclerosis.Formins: emerging players in the dynamic plant cell cortexTwo-photon microscopy reveals stationary podocytes in living zebrafish larvae.Formin' cellular structures: Physiological roles of Diaphanous (Dia) in actin dynamics.STK16 regulates actin dynamics to control Golgi organization and cell cycleRole of Rho-GTPases and their regulatory proteins in glomerular podocyte function.Neuropathologic characterization of INF2-related Charcot-Marie-Tooth disease: evidence for a Schwann cell actinopathy.Podocyte-actin dynamics in health and disease.Disease modeling in genetic kidney diseases: zebrafish.Human Kidney Disease-causing INF2 Mutations Perturb Rho/Dia Signaling in the Glomerulus.Novel pleiotropic effects of bioactive phospholipids in human lung cancer metastasis.mDia1-3 in mammalian filopodia.Mice with mutant Inf2 show impaired podocyte and slit diaphragm integrity in response to protamine-induced kidney injuryCentrosome polarization in T cells: a task for forminsA network of conserved formins, regulated by the guanine exchange factor EXC-5 and the GTPase CDC-42, modulates tubulogenesis in vivo.Inverted formins: A subfamily of atypical formins.Non-muscle myosins and the podocyte.Molecular Mechanisms of Proteinuria in Focal Segmental Glomerulosclerosis.
P2860
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P2860
Rho activation of mDia formins is modulated by an interaction with inverted formin 2 (INF2)
description
2011 nî lūn-bûn
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2011 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2011年の論文
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2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Rho activation of mDia formins ...... with inverted formin 2 (INF2)
@ast
Rho activation of mDia formins ...... with inverted formin 2 (INF2)
@en
Rho activation of mDia formins is modulated by an interaction with inverted formin 2
@nl
type
label
Rho activation of mDia formins ...... with inverted formin 2 (INF2)
@ast
Rho activation of mDia formins ...... with inverted formin 2 (INF2)
@en
Rho activation of mDia formins is modulated by an interaction with inverted formin 2
@nl
prefLabel
Rho activation of mDia formins ...... with inverted formin 2 (INF2)
@ast
Rho activation of mDia formins ...... with inverted formin 2 (INF2)
@en
Rho activation of mDia formins is modulated by an interaction with inverted formin 2
@nl
P2093
P2860
P356
P1476
Rho activation of mDia formins ...... with inverted formin 2 (INF2)
@en
P2093
Elizabeth J Brown
Martin R Pollak
P2860
P304
P356
10.1073/PNAS.1017010108
P407
P577
2011-01-28T00:00:00Z