Modulation of poliovirus replicative fitness in HeLa cells by deoptimization of synonymous codon usage in the capsid region.
about
Fine-tuning translation kinetics selection as the driving force of codon usage bias in the hepatitis A virus capsidRecombination and selection in the evolution of picornaviruses and other Mammalian positive-stranded RNA virusesThe distribution of synonymous codon choice in the translation initiation region of dengue virusVirus attenuation by genome-scale changes in codon pair biasSynthetic viruses: a new opportunity to understand and prevent viral diseaseDevelopment of next-generation respiratory virus vaccines through targeted modifications to viral immunomodulatory genesViral quasispecies evolutionUtilisation of ISA Reverse Genetics and Large-Scale Random Codon Re-Encoding to Produce Attenuated Strains of Tick-Borne Encephalitis Virus within DaysVaccines: the Fourth CenturyCRPV genomes with synonymous codon optimizations in the CRPV E7 gene show phenotypic differences in growth and altered immunity upon E7 vaccinationCharacterization of Viral Populations by Using Circular SequencingFurther studies on the role of the residue 890 cysteine to tyrosine mutation in the M70 primase ORF of the temperature-sensitive mutant (tsm5) of murine cytomegalovirus.Pandemic influenza A virus codon usage revisited: biases, adaptation and implications for vaccine strain developmentRandom codon re-encoding induces stable reduction of replicative fitness of Chikungunya virus in primate and mosquito cellsRCDI/eRCDI: a web-server to estimate codon usage deoptimization.RNA virus reverse genetics and vaccine design.Rationalizing the development of live attenuated virus vaccinesRefining the balance of attenuation and immunogenicity of respiratory syncytial virus by targeted codon deoptimization of virulence genesIdentification of two functionally redundant RNA elements in the coding sequence of poliovirus using computer-generated designLarge-scale de novo DNA synthesis: technologies and applications.Reduction of the rate of poliovirus protein synthesis through large-scale codon deoptimization causes attenuation of viral virulence by lowering specific infectivityModelling mutational and selection pressures on dinucleotides in eukaryotic phyla--selection against CpG and UpA in cytoplasmically expressed RNA and in RNA virusesAttenuation of tick-borne encephalitis virus using large-scale random codon re-encodingFRESCo: finding regions of excess synonymous constraint in diverse virusesDevelopment of live-attenuated arenavirus vaccines based on codon deoptimizationDownregulating viral gene expression: codon usage bias manipulation for the generation of novel influenza A virus vaccines.An attenuated strain of enterovirus 71 belonging to genotype a showed a broad spectrum of antigenicity with attenuated neurovirulence in cynomolgus monkeys.High-Throughput Next-Generation Sequencing of Polioviruses.Slow fitness recovery in a codon-modified viral genome.Synonymous Deoptimization of Foot-and-Mouth Disease Virus Causes Attenuation In Vivo while Inducing a Strong Neutralizing Antibody Response.Elevation of CpG frequencies in influenza A genome attenuates pathogenicity but enhances host response to infection.Evolutionary reversion of live viral vaccines: Can genetic engineering subdue it?Multiple independent emergences of type 2 vaccine-derived polioviruses during a large outbreak in northern NigeriaNew generation of inactivated poliovirus vaccines for universal immunization after eradication of poliomyelitis.Changes in codon-pair bias of human immunodeficiency virus type 1 have profound effects on virus replication in cell culture.A Recombinant Respiratory Syncytial Virus Vaccine Candidate Attenuated by a Low-Fusion F Protein Is Immunogenic and Protective against Challenge in Cotton RatsCodonShuffle: a tool for generating and analyzing synonymously mutated sequences.Genetic inactivation of poliovirus infectivity by increasing the frequencies of CpG and UpA dinucleotides within and across synonymous capsid region codons.Prospects for improved bluetongue vaccines.Development of live-attenuated arenavirus vaccines based on codon deoptimization of the viral glycoprotein.
P2860
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P2860
Modulation of poliovirus replicative fitness in HeLa cells by deoptimization of synonymous codon usage in the capsid region.
description
2006 nî lūn-bûn
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2006 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի ապրիլին հրատարակված գիտական հոդված
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2006年の論文
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2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Modulation of poliovirus repli ...... on usage in the capsid region.
@ast
Modulation of poliovirus repli ...... on usage in the capsid region.
@en
Modulation of poliovirus repli ...... on usage in the capsid region.
@nl
type
label
Modulation of poliovirus repli ...... on usage in the capsid region.
@ast
Modulation of poliovirus repli ...... on usage in the capsid region.
@en
Modulation of poliovirus repli ...... on usage in the capsid region.
@nl
prefLabel
Modulation of poliovirus repli ...... on usage in the capsid region.
@ast
Modulation of poliovirus repli ...... on usage in the capsid region.
@en
Modulation of poliovirus repli ...... on usage in the capsid region.
@nl
P2093
P2860
P1433
P1476
Modulation of poliovirus repli ...... don usage in the capsid region
@en
P2093
Annelet Vincent
Cara Carthel Burns
Jacqueline Quay
Jaume Jorba
P2860
P304
P356
10.1128/JVI.80.7.3259-3272.2006
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P577
2006-04-01T00:00:00Z