The Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen 1 N terminus is essential for chromosome association, DNA replication, and episome persistence
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Latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus recruits uracil DNA glycosylase 2 at the terminal repeats and is important for latent persistence of the virusKaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen interacts with bromodomain protein Brd4 on host mitotic chromosomesKaposi's Sarcoma Herpesvirus Genome PersistenceKSHV: pathways to tumorigenesis and persistent infectionViral Genome Tethering to Host Cell Chromatin: Cause and ConsequencesAssay Development and High-Throughput Screening for Inhibitors of Kaposi's Sarcoma-Associated Herpesvirus N-Terminal Latency-Associated Nuclear Antigen Binding to Nucleosomes.Kaposi's sarcoma-associated herpesvirus-encoded LANA can interact with the nuclear mitotic apparatus protein to regulate genome maintenance and segregation.Intrabodies targeting the Kaposi sarcoma-associated herpesvirus latency antigen inhibit viral persistence in lymphoma cells.Molecular biology of KSHV in relation to AIDS-associated oncogenesis.A central region in the minor capsid protein of papillomaviruses facilitates viral genome tethering and membrane penetration for mitotic nuclear entry.The latency-associated nuclear antigen of rhesus monkey rhadinovirus inhibits viral replication through repression of Orf50/Rta transcriptional activation.Conservation of complex nuclear localization signals utilizing classical and non-classical nuclear import pathways in LANA homologs of KSHV and RFHVKaposi's sarcoma-associated herpesvirus LANA recruits the DNA polymerase clamp loader to mediate efficient replication and virus persistenceUnbiased mutagenesis of MHV68 LANA reveals a DNA-binding domain required for LANA function in vitro and in vivo.Mitotic chromosome-binding activity of latency-associated nuclear antigen 1 is required for DNA replication from terminal repeat sequence of Kaposi's sarcoma-associated herpesvirusMechanisms of Kaposi's Sarcoma-Associated Herpesvirus Latency and ReactivationRecruitment of the de novo DNA methyltransferase Dnmt3a by Kaposi's sarcoma-associated herpesvirus LANANucleosome acidic patch promotes RNF168- and RING1B/BMI1-dependent H2AX and H2A ubiquitination and DNA damage signaling.Structure and function of latency-associated nuclear antigen.Rapid and quantitative assessment of KSHV LANA-mediated DNA replication.Kaposi's sarcoma-associated herpesvirus LANA-1 interacts with the short variant of BRD4 and releases cells from a BRD4- and BRD2/RING3-induced G1 cell cycle arrest.The internal Kaposi's sarcoma-associated herpesvirus LANA regions exert a critical role on episome persistenceInhibition of infection and replication of human herpesvirus 8 in microvascular endothelial cells by alpha interferon and phosphonoformic acidDetermination of Kaposi's sarcoma-associated herpesvirus C-terminal latency-associated nuclear antigen residues mediating chromosome association and DNA binding.Analysis of viral cis elements conferring Kaposi's sarcoma-associated herpesvirus episome partitioning and maintenance.The Kaposi's sarcoma-associated herpesvirus LANA protein stabilizes and activates c-Myc.The Kaposi Sarcoma Herpesvirus Latency-associated Nuclear Antigen DNA Binding Domain Dorsal Positive Electrostatic Patch Facilitates DNA Replication and Episome Persistence.Murine gammaherpesvirus 68 LANA acts on terminal repeat DNA to mediate episome persistence.Cytoplasmic isoforms of Kaposi sarcoma herpesvirus LANA recruit and antagonize the innate immune DNA sensor cGASKSHV but not MHV-68 LANA induces a strong bend upon binding to terminal repeat viral DNA.The EBNA1 protein of Epstein-Barr virus functionally interacts with Brd4Role of Kaposi's sarcoma-associated herpesvirus C-terminal LANA chromosome binding in episome persistence.Preparation and application of polyclonal antibodiesagainst KSHV v-cyclin.Identification of Kaposi's sarcoma-associated herpesvirus LANA regions important for episome segregation, replication, and persistence.A short sequence immediately upstream of the internal repeat elements is critical for KSHV LANA mediated DNA replication and impacts episome persistenceThe latency-associated nuclear antigen, a multifunctional protein central to Kaposi's sarcoma-associated herpesvirus latency.Involvement of SSRP1 in latent replication of Kaposi's sarcoma-associated herpesvirusRepression of the Chromatin-Tethering Domain of Murine Leukemia Virus p12.A lytic viral long noncoding RNA modulates the function of a latent protein.The amino terminus of Epstein-Barr Virus (EBV) nuclear antigen 1 contains AT hooks that facilitate the replication and partitioning of latent EBV genomes by tethering them to cellular chromosomes
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The Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen 1 N terminus is essential for chromosome association, DNA replication, and episome persistence
description
2004 nî lūn-bûn
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2004 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հունվարին հրատարակված գիտական հոդված
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2004年の論文
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2004年学术文章
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2004年学术文章
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2004年学术文章
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2004年学术文章
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2004年学术文章
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2004年學術文章
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name
The Kaposi's sarcoma-associate ...... ation, and episome persistence
@ast
The Kaposi's sarcoma-associate ...... ation, and episome persistence
@en
The Kaposi's sarcoma-associate ...... ation, and episome persistence
@nl
type
label
The Kaposi's sarcoma-associate ...... ation, and episome persistence
@ast
The Kaposi's sarcoma-associate ...... ation, and episome persistence
@en
The Kaposi's sarcoma-associate ...... ation, and episome persistence
@nl
prefLabel
The Kaposi's sarcoma-associate ...... ation, and episome persistence
@ast
The Kaposi's sarcoma-associate ...... ation, and episome persistence
@en
The Kaposi's sarcoma-associate ...... ation, and episome persistence
@nl
P2860
P1433
P1476
The Kaposi's sarcoma-associate ...... ation, and episome persistence
@en
P2093
Andrew J Barbera
Kenneth M Kaye
P2860
P304
P356
10.1128/JVI.78.1.294-301.2004
P407
P577
2004-01-01T00:00:00Z