Identification of the 64K autoantigen in insulin-dependent diabetes as the GABA-synthesizing enzyme glutamic acid decarboxylase.
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Teratogenic mechanisms of medical drugsTwo human glutamate decarboxylases, 65-kDa GAD and 67-kDa GAD, are each encoded by a single geneCloning and characterization of islet cell antigen-related protein-tyrosine phosphatase (PTP), a novel receptor-like PTP and autoantigen in insulin-dependent diabetesAutoimmunity to two forms of glutamate decarboxylase in insulin-dependent diabetes mellitusICA 512, an autoantigen of type I diabetes, is an intrinsic membrane protein of neurosecretory granulesIdentification of a second transmembrane protein tyrosine phosphatase, IA-2beta, as an autoantigen in insulin-dependent diabetes mellitus: precursor of the 37-kDa tryptic fragmentIslet cell autoantigen 69 kD (ICA69). Molecular cloning and characterization of a novel diabetes-associated autoantigenQuantitative assay using recombinant human islet glutamic acid decarboxylase (GAD65) shows that 64K autoantibody positivity at onset predicts diabetes typeCNS immune privilege: hiding in plain sight.The cation efflux transporter ZnT8 (Slc30A8) is a major autoantigen in human type 1 diabetesIdentification of the beta cell antigen targeted by a prevalent population of pathogenic CD8+ T cells in autoimmune diabetes.Severe anaphylactic reactions to glutamic acid decarboxylase (GAD) self peptides in NOD mice that spontaneously develop autoimmune type 1 diabetes mellitusThe Role of Gluten in Celiac Disease and Type 1 DiabetesEnterovirus and type 1 diabetes: What is the matter?Islet cell transplantation for the treatment of type 1 diabetes: recent advances and future challengesNovel diabetes autoantibodies and prediction of type 1 diabetesRecombinant Lactococcus lactis can make the difference in antigen-specific immune tolerance induction, the Type 1 Diabetes caseStructure of a human insulin peptide-HLA-DQ8 complex and susceptibility to type 1 diabetesGABA production by glutamic acid decarboxylase is regulated by a dynamic catalytic loopAntigen Presentation, Autoantigens, and Immune Regulation in Multiple Sclerosis and Other Autoimmune DiseasesImmunogenetics of type 1 diabetes mellitusAromatic-L-amino-acid decarboxylase, a pyridoxal phosphate-dependent enzyme, is a beta-cell autoantigenA type 1 diabetes-related protein from wheat (Triticum aestivum). cDNA clone of a wheat storage globulin, Glb1, linked to islet damageMuscle autoantigens in thyroid associated ophthalmopathy: the limits of molecular geneticsAutoimmune stiff person syndrome and related myelopathies: understanding of electrophysiological and immunological processes.The diabetes autoantigen ICA69 and its Caenorhabditis elegans homologue, ric-19, are conserved regulators of neuroendocrine secretionAutoimmune type 1 diabetes: resolved and unresolved issuesIslet glutamic acid decarboxylase modified by reactive oxygen species is recognized by antibodies from patients with type 1 diabetes mellitusCharacterisation of peptide microarrays for studying antibody-antigen binding using surface plasmon resonance imageryExpression of neurexin, neuroligin, and their cytoplasmic binding partners in the pancreatic beta-cells and the involvement of neuroligin in insulin secretionPotential of protein phosphatase inhibitor 1 as biomarker of pancreatic β-cell injury in vitro and in vivoTargeting of the 67-kDa isoform of glutamic acid decarboxylase to intracellular organelles is mediated by its interaction with the NH2-terminal region of the 65-kDa isoform of glutamic acid decarboxylasePhosphorylation of serine residues 3, 6, 10, and 13 distinguishes membrane anchored from soluble glutamic acid decarboxylase 65 and is restricted to glutamic acid decarboxylase 65alphaCloning, characterization, and autoimmune recognition of rat islet glutamic acid decarboxylase in insulin-dependent diabetes mellitusAdditive and interaction effects at three amino acid positions in HLA-DQ and HLA-DR molecules drive type 1 diabetes riskLong latency between GAD-antibody detection and development of limbic encephalitis--a case report.Guidelines and recommendations for laboratory analysis in the diagnosis and management of diabetes mellitus.GAD65 antibodies, chronic psychosis, and type 2 diabetes mellitusCofactor-dependent conformational heterogeneity of GAD65 and its role in autoimmunity and neurotransmitter homeostasisSex steroid regulation of glutamate decarboxylase mRNA expression in goldfish brain is sexually dimorphic.
P2860
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P2860
Identification of the 64K autoantigen in insulin-dependent diabetes as the GABA-synthesizing enzyme glutamic acid decarboxylase.
description
1990 nî lūn-bûn
@nan
1990 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1990 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
name
Identification of the 64K auto ...... e glutamic acid decarboxylase.
@ast
Identification of the 64K auto ...... e glutamic acid decarboxylase.
@en
Identification of the 64K auto ...... e glutamic acid decarboxylase.
@nl
type
label
Identification of the 64K auto ...... e glutamic acid decarboxylase.
@ast
Identification of the 64K auto ...... e glutamic acid decarboxylase.
@en
Identification of the 64K auto ...... e glutamic acid decarboxylase.
@nl
prefLabel
Identification of the 64K auto ...... e glutamic acid decarboxylase.
@ast
Identification of the 64K auto ...... e glutamic acid decarboxylase.
@en
Identification of the 64K auto ...... e glutamic acid decarboxylase.
@nl
P2093
P356
P1433
P1476
Identification of the 64K auto ...... e glutamic acid decarboxylase.
@en
P2093
Aanstoot HJ
Baekkeskov S
Cascalho M
Christgau S
De Camilli P
Richter-Olesen H
Solimena M
P2888
P304
P356
10.1038/347151A0
P407
P577
1990-09-01T00:00:00Z
P6179
1016714750