Oxidative stress in ALS: a mechanism of neurodegeneration and a therapeutic target.
about
Dysregulation of the autophagy-endolysosomal system in amyotrophic lateral sclerosis and related motor neuron diseasesMutation of SOD1 in ALS: a gain of a loss of functionSOD1 mutations disrupt redox-sensitive Rac regulation of NADPH oxidase in a familial ALS modelMitochondrial ubiquitin ligase MITOL ubiquitinates mutant SOD1 and attenuates mutant SOD1-induced reactive oxygen species generationUpregulation of the E3 ligase NEDD4-1 by oxidative stress degrades IGF-1 receptor protein in neurodegenerationNitric oxide and peroxynitrite in health and diseaseRedox Characterization of Functioning Skeletal MuscleTempol moderately extends survival in a hSOD1(G93A) ALS rat model by inhibiting neuronal cell loss, oxidative damage and levels of non-native hSOD1(G93A) formsRedox modification of proteins as essential mediators of CNS autophagy and mitophagy.Systems biology of neurodegenerative diseasesRedox regulation of mitochondrial functionThioredoxins, glutaredoxins, and peroxiredoxins--molecular mechanisms and health significance: from cofactors to antioxidants to redox signalingClinical perspective on oxidative stress in sporadic amyotrophic lateral sclerosisMitochondria-ros crosstalk in the control of cell death and agingInduction of phase 2 antioxidant enzymes by broccoli sulforaphane: perspectives in maintaining the antioxidant activity of vitamins a, C, and eRiluzole increases the amount of latent HSF1 for an amplified heat shock response and cytoprotectionLack of effect of methylene blue in the SOD1 G93A mouse model of amyotrophic lateral sclerosisBromocriptine Mesylate Attenuates Amyotrophic Lateral Sclerosis: A Phase 2a, Randomized, Double-Blind, Placebo-Controlled Research in Japanese PatientsImpact of treadmill running and sex on hippocampal neurogenesis in the mouse model of amyotrophic lateral sclerosisAmyotrophic lateral sclerosis multiprotein biomarkers in peripheral blood mononuclear cellsR+ pramipexole as a mitochondrially focused neuroprotectant: initial early phase studies in ALS.Inactivation of the SMN complex by oxidative stressMessenger RNA oxidation occurs early in disease pathogenesis and promotes motor neuron degeneration in ALSChanges in the spinal cord proteome of an amyotrophic lateral sclerosis murine model determined by differential in-gel electrophoresis.An in vitro screening cascade to identify neuroprotective antioxidants in ALSCaloric restriction shortens lifespan through an increase in lipid peroxidation, inflammation and apoptosis in the G93A mouse, an animal model of ALS.DNA-triggered aggregation of copper, zinc superoxide dismutase in the presence of ascorbate.Redox modifier genes and pathways in amyotrophic lateral sclerosis.Predicting disease onset in clinically healthy peoplePathological correlations between traumatic brain injury and chronic neurodegenerative diseases.Diagnosis and management of motor neurone disease.Physical activity as an exogenous risk factor in motor neuron disease (MND): a review of the evidence.Nuclear TAR DNA-binding protein 43: A new target for amyotrophic lateral sclerosis treatmentC-Jun N-terminal kinase controls TDP-43 accumulation in stress granules induced by oxidative stressFunctions of FUS/TLS from DNA repair to stress response: implications for ALS.Mutant FUS proteins that cause amyotrophic lateral sclerosis incorporate into stress granulesElevated serum ferritin is associated with reduced survival in amyotrophic lateral sclerosis.S[+] Apomorphine is a CNS penetrating activator of the Nrf2-ARE pathway with activity in mouse and patient fibroblast models of amyotrophic lateral sclerosisThe carbonylation and covalent dimerization of human superoxide dismutase 1 caused by its bicarbonate-dependent peroxidase activity is inhibited by the radical scavenger tempol.Recent advances in our understanding of neurodegeneration.
P2860
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P2860
Oxidative stress in ALS: a mechanism of neurodegeneration and a therapeutic target.
description
2006 nî lūn-bûn
@nan
2006 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Oxidative stress in ALS: a mechanism of neurodegeneration and a therapeutic target.
@ast
Oxidative stress in ALS: a mechanism of neurodegeneration and a therapeutic target.
@en
Oxidative stress in ALS: a mechanism of neurodegeneration and a therapeutic target.
@nl
type
label
Oxidative stress in ALS: a mechanism of neurodegeneration and a therapeutic target.
@ast
Oxidative stress in ALS: a mechanism of neurodegeneration and a therapeutic target.
@en
Oxidative stress in ALS: a mechanism of neurodegeneration and a therapeutic target.
@nl
prefLabel
Oxidative stress in ALS: a mechanism of neurodegeneration and a therapeutic target.
@ast
Oxidative stress in ALS: a mechanism of neurodegeneration and a therapeutic target.
@en
Oxidative stress in ALS: a mechanism of neurodegeneration and a therapeutic target.
@nl
P1476
Oxidative stress in ALS: a mechanism of neurodegeneration and a therapeutic target.
@en
P2093
Siân C Barber
P304
P356
10.1016/J.BBADIS.2006.03.008
P407
P577
2006-04-04T00:00:00Z