The roles of helix I and strand 5A in the folding, function and misfolding of α1-antitrypsin.
about
AFM Imaging Reveals Topographic Diversity of Wild Type and Z Variant Polymers of Human α1-Proteinase InhibitorCollapse of a long axis: single-molecule Förster resonance energy transfer and serpin equilibrium unfolding.Altered native stability is the dominant basis for susceptibility of α1-antitrypsin mutants to polymerization.Smoothing a rugged protein folding landscape by sequence-based redesign.An antibody that prevents serpin polymerisation acts by inducing a novel allosteric behaviour.An antibody raised against a pathogenic serpin variant induces mutant-like behaviour in the wild-type protein.The pathological Trento variant of alpha-1-antitrypsin (E75V) shows nonclassical behaviour during polymerization.Probing the folding pathway of a consensus serpin using single tryptophan mutants.On the folding of a structurally complex protein to its metastable active state.
P2860
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P2860
The roles of helix I and strand 5A in the folding, function and misfolding of α1-antitrypsin.
description
2013 nî lūn-bûn
@nan
2013 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
The roles of helix I and stran ...... misfolding of α1-antitrypsin.
@ast
The roles of helix I and stran ...... misfolding of α1-antitrypsin.
@en
The roles of helix I and stran ...... misfolding of α1-antitrypsin.
@nl
type
label
The roles of helix I and stran ...... misfolding of α1-antitrypsin.
@ast
The roles of helix I and stran ...... misfolding of α1-antitrypsin.
@en
The roles of helix I and stran ...... misfolding of α1-antitrypsin.
@nl
prefLabel
The roles of helix I and stran ...... misfolding of α1-antitrypsin.
@ast
The roles of helix I and stran ...... misfolding of α1-antitrypsin.
@en
The roles of helix I and stran ...... misfolding of α1-antitrypsin.
@nl
P2093
P2860
P1433
P1476
The roles of helix I and stran ...... misfolding of α1-antitrypsin.
@en
P2093
Mary C Pearce
Shani Keleher
Stephen P Bottomley
Weiwen Dai
P2860
P304
P356
10.1371/JOURNAL.PONE.0054766
P407
P577
2013-01-29T00:00:00Z