Mutations in Mre11 phosphoesterase motif I that impair Saccharomyces cerevisiae Mre11-Rad50-Xrs2 complex stability in addition to nuclease activity
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DNA end resection: many nucleases make light workMre11 Dimers Coordinate DNA End Bridging and Nuclease Processing in Double-Strand-Break RepairMre11 ATLD17/18 mutation retains Tel1/ATM activity but blocks DNA double-strand break repairDifferences in the DNA replication of unicellular eukaryotes and metazoans: known unknownsMre11 and Ku regulation of double-strand break repair by gene conversion and break-induced replication.Recruitment and dissociation of nonhomologous end joining proteins at a DNA double-strand break in Saccharomyces cerevisiae.Relative contribution of four nucleases, CtIP, Dna2, Exo1 and Mre11, to the initial step of DNA double-strand break repair by homologous recombination in both the chicken DT40 and human TK6 cell linesFormation of linear amplicons with inverted duplications in Leishmania requires the MRE11 nucleaseThe role of the Mre11-Rad50-Nbs1 complex in double-strand break repair-facts and mythsSae2 promotes DNA damage resistance by removing the Mre11-Rad50-Xrs2 complex from DNA and attenuating Rad53 signaling.Identification of Plasmodium falciparum DNA Repair Protein Mre11 with an Evolutionarily Conserved Nuclease FunctionDouble-strand break repair pathways protect against CAG/CTG repeat expansions, contractions and repeat-mediated chromosomal fragility in Saccharomyces cerevisiaeThe rad52-Y66A allele alters the choice of donor template during spontaneous chromosomal recombinationMRE11 function in response to topoisomerase poisons is independent of its function in double-strand break repair in Saccharomyces cerevisiaeMre11 nuclease activity and Ctp1 regulate Chk1 activation by Rad3ATR and Tel1ATM checkpoint kinases at double-strand breaks.Release of Ku and MRN from DNA ends by Mre11 nuclease activity and Ctp1 is required for homologous recombination repair of double-strand breaks.Ku prevents Exo1 and Sgs1-dependent resection of DNA ends in the absence of a functional MRX complex or Sae2Optimization of ordered plasmid assembly by gap repair in Saccharomyces cerevisiae.Synthetic viability genomic screening defines Sae2 function in DNA repair.Chromosome integrity at a double-strand break requires exonuclease 1 and MRXCoincident resection at both ends of random, γ-induced double-strand breaks requires MRX (MRN), Sae2 (Ctp1), and Mre11-nucleaseDNA repair factor MRE11/RAD50 cleaves 3'-phosphotyrosyl bonds and resects DNA to repair damage caused by topoisomerase 1 poisons.Unique and overlapping functions of the Exo1, Mre11 and Pso2 nucleases in DNA repair.S. cerevisiae Mre11 recruits conjugated SUMO moieties to facilitate the assembly and function of the Mre11-Rad50-Xrs2 complex.Processing of DNA double-stranded breaks and intermediates of recombination and repair by Saccharomyces cerevisiae Mre11 and its stimulation by Rad50, Xrs2, and Sae2 proteins.Identification of the Xenopus DNA2 protein as a major nuclease for the 5'->3' strand-specific processing of DNA ends.Impaired resection of meiotic double-strand breaks channels repair to nonhomologous end joining in Caenorhabditis elegans.Mre11 nuclease activity has essential roles in DNA repair and genomic stability distinct from ATM activation.Mechanism and regulation of DNA end resection in eukaryotesThe role of MRN in the S-phase DNA damage checkpoint is independent of its Ctp1-dependent roles in double-strand break repair and checkpoint signaling.Coordination and processing of DNA ends during double-strand break repair: the role of the bacteriophage T4 Mre11/Rad50 (MR) complex.Meiotic DNA double-strand break repair requires two nucleases, MRN and Ctp1, to produce a single size class of Rec12 (Spo11)-oligonucleotide complexes.DNA repair pathways in trypanosomatids: from DNA repair to drug resistance.Genetic and biochemical evidences reveal novel insights into the mechanism underlying Saccharomyces cerevisiae Sae2-mediated abrogation of DNA replication stress.The MRX complex plays multiple functions in resection of Yku- and Rif2-protected DNA endsDistinct requirements for the Rad32(Mre11) nuclease and Ctp1(CtIP) in the removal of covalently bound topoisomerase I and II from DNA.Xrs2 Dependent and Independent Functions of the Mre11-Rad50 ComplexCtp1CtIP and Rad32Mre11 nuclease activity are required for Rec12Spo11 removal, but Rec12Spo11 removal is dispensable for other MRN-dependent meiotic functions.The MRX complex stabilizes the replisome independently of the S phase checkpoint during replication stress.Telomerase- and Rad52-independent immortalization of budding yeast by an inherited-long-telomere pathway of telomeric repeat amplification.
P2860
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P2860
Mutations in Mre11 phosphoesterase motif I that impair Saccharomyces cerevisiae Mre11-Rad50-Xrs2 complex stability in addition to nuclease activity
description
2005 nî lūn-bûn
@nan
2005 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
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2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Mutations in Mre11 phosphoeste ...... addition to nuclease activity
@ast
Mutations in Mre11 phosphoeste ...... addition to nuclease activity
@en
Mutations in Mre11 phosphoeste ...... addition to nuclease activity
@nl
type
label
Mutations in Mre11 phosphoeste ...... addition to nuclease activity
@ast
Mutations in Mre11 phosphoeste ...... addition to nuclease activity
@en
Mutations in Mre11 phosphoeste ...... addition to nuclease activity
@nl
prefLabel
Mutations in Mre11 phosphoeste ...... addition to nuclease activity
@ast
Mutations in Mre11 phosphoeste ...... addition to nuclease activity
@en
Mutations in Mre11 phosphoeste ...... addition to nuclease activity
@nl
P2093
P2860
P1433
P1476
Mutations in Mre11 phosphoeste ...... addition to nuclease activity
@en
P2093
Alicia Lam
Berit O Krogh
Bertrand Llorente
Lorraine S Symington
P2860
P304
P356
10.1534/GENETICS.105.049478
P407
P577
2005-09-02T00:00:00Z