Peripheral deletional tolerance of alloreactive CD8 but not CD4 T cells is dependent on the PD-1/PD-L1 pathway - Wikidata - awgldk - TriplyDB

Peripheral deletional tolerance of alloreactive CD8 but not CD4 T cells is dependent on the PD-1/PD-L1 pathway

Peripheral deletional tolerance of alloreactive CD8 but not CD4 T cells is dependent on the PD-1/PD-L1 pathway

http://www.wikidata.org/entity/Q34593527

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Immuno-intervention for the induction of transplantation tolerance through mixed chimerism Prognostic value of programmed cell death-ligand 1 expression in patients with non-small-cell lung cancer: evidence from an updated meta-analysis.Genetic barriers in transplantation medicine The CD8 T-cell response during tolerance induction in liver transplantation A CD8 T cell-intrinsic role for the calcineurin-NFAT pathway for tolerance induction in vivo.Alloantigen expression on non-hematopoietic cells reduces graft-versus-leukemia effects in mice.LAG-3, TGF-β, and cell-intrinsic PD-1 inhibitory pathways contribute to CD8 but not CD4 T-cell tolerance induced by allogeneic BMT with anti-CD40L.Costimulatory pathways in transplantation.Prevention of airway allograft tolerance by polyinosinic:polycytidylic acid requires type I interferon responsiveness for mouse airway obliteration Recipient dendritic cells, but not B cells, are required antigen-presenting cells for peripheral alloreactive CD8+ T-cell tolerance.PD-L1 blockade effectively restores strong graft-versus-leukemia effects without graft-versus-host disease after delayed adoptive transfer of T-cell receptor gene-engineered allogeneic CD8+ T cells.Upregulation of PD-L1 and APE1 is associated with tumorigenesis and poor prognosis of gastric cancer.A repertoire-independent and cell-intrinsic defect in murine GVHD induction by effector memory T cells.Resistance to ABT-737 in activated T lymphocytes: molecular mechanisms and reversibility by inhibition of the calcineurin-NFAT pathway.The association between PD-L1 and EGFR status and the prognostic value of PD-L1 in advanced non-small cell lung cancer patients treated with EGFR-TKIs Polymorphisms of co-inhibitory molecules (CTLA-4/PD-1/PD-L1) and the risk of non-small cell lung cancer in a Chinese population TGFβ-dependent expression of PD-1 and PD-L1 controls CD8(+) T cell anergy in transplant tolerance PD-1 rs2227982 Polymorphism Is Associated With the Decreased Risk of Breast Cancer in Northwest Chinese Women: A Hospital-Based Observational Study.CD154 deficiency uncouples allograft CD8+ T-cell effector function from proliferation and inhibits murine airway obliteration Hematopoietic cell transplantation for tolerance induction: animal models to clinical trials Host bone marrow-derived IL-12 enhances donor T cell engraftment in a mouse model of bone marrow transplantation.Immune tolerance and transplantation.Modulation of tumor immunity by soluble and membrane-bound molecules at the immunological synapse.Induction of tolerance through mixed chimerism.Haploidentical SCT: the mechanisms underlying the crossing of HLA barriers.T-cell exhaustion: understanding the interface of chronic viral and autoinflammatory diseases.Tracking of TCR-Transgenic T Cells Reveals That Multiple Mechanisms Maintain Cardiac Transplant Tolerance in Mice.The IL-1R/TLR signaling pathway is essential for efficient CD8(+) T-cell responses against hepatitis B virus in the hydrodynamic injection mouse model.B-cell-dependent memory T cells impede nonmyeloablative mixed chimerism induction in presensitized mice.Layers of regulation in induction of mixed chimerism by anti-CD40L.CD154 blockade abrogates allospecific responses and enhances CD4(+) regulatory T-cells in mouse orthotopic lung transplant.Mechanisms of Mixed Chimerism-Based Transplant Tolerance.

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Peripheral deletional tolerance of alloreactive CD8 but not CD4 T cells is dependent on the PD-1/PD-L1 pathway

http://www.wikidata.org/entity/Q34593527

description

2008 nî lūn-bûn

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2008 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2008 թվականի հունիսին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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name

Peripheral deletional toleranc ...... dent on the PD-1/PD-L1 pathway

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Peripheral deletional toleranc ...... dent on the PD-1/PD-L1 pathway

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Peripheral deletional toleranc ...... dent on the PD-1/PD-L1 pathway

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Peripheral deletional toleranc ...... dent on the PD-1/PD-L1 pathway

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Peripheral deletional toleranc ...... dent on the PD-1/PD-L1 pathway

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Peripheral deletional toleranc ...... dent on the PD-1/PD-L1 pathway

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Peripheral deletional toleranc ...... dent on the PD-1/PD-L1 pathway

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Carrie Gibbons

http://www.w3.org/2001/XMLSchema#string

Fabienne Haspot

http://www.w3.org/2001/XMLSchema#string

Gordon J Freeman

http://www.w3.org/2001/XMLSchema#string

Guiling Zhao

http://www.w3.org/2001/XMLSchema#string

Megan Sykes

http://www.w3.org/2001/XMLSchema#string

Thomas Fehr

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Timothy Hogan

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P2860

Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor

PD-L2 is a second ligand for PD-1 and inhibits T cell activation

Expression of programmed death 1 ligands by murine T cells and APC

The B7 family revisited

Expression of the PD-1 antigen on the surface of stimulated mouse T and B lymphocytes

Restoring function in exhausted CD8 T cells during chronic viral infection

PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression

Peripheral deletion after bone marrow transplantation with costimulatory blockade has features of both activation-induced cell death and passive cell death.

Cutting Edge: Programmed death (PD) ligand-1/PD-1 interaction is required for CD8+ T cell tolerance to tissue antigens.

PDL1 is required for peripheral transplantation tolerance and protection from chronic allograft rejection.

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2518911

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