Structural model for gamma-aminobutyric acid receptor noncompetitive antagonist binding: widely diverse structures fit the same site
about
Ionotropic GABA receptor antagonism-induced adverse outcome pathways for potential neurotoxicity biomarkersImmunologic and neurodevelopmental susceptibilities of autismThe dual modulatory effects of efavirenz on GABAA receptors are mediated via two distinct sites.Kinetic analysis of evoked IPSCs discloses mechanism of antagonism of synaptic GABAA receptors by picrotoxin.GABAA receptor target of tetramethylenedisulfotetraminePharmacological characterization of GABAA receptors in taurine-fed mice.Differential mechanisms of action of the novel γ-aminobutyric acid receptor antagonist ectoparasiticides fluralaner (A1443) and fipronil.Rapid Throughput Analysis of GABAA Receptor Subtype Modulators and Blockers Using DiSBAC1(3) Membrane Potential Red Dye.Picrotoxin-like channel blockers of GABAA receptorsGinkgolide B and bilobalide block the pore of the 5-HT₃receptor at a location that overlaps the picrotoxin binding siteHydrophobic anions potently and uncompetitively antagonize GABA(A) receptor function in the absence of a conventional binding siteMeroterpenoid Chrodrimanins Are Selective and Potent Blockers of Insect GABA-Gated Chloride Channels.A single amino acid determines the toxicity of Ginkgo biloba extracts.Mapping convulsants' binding to the GABA-A receptor chloride ionophore: a proposed model for channel binding sites.Inhibitor Discovery for the Human GLUT1 from Homology Modeling and Virtual ScreeningMechanism of action of the insecticides, lindane and fipronil, on glycine receptor chloride channels.The pharmacological profile of ELIC, a prokaryotic GABA-gated receptorMixed antagonistic effects of the ginkgolides at recombinant human ρ1 GABAC receptorsModular design of Cys-loop ligand-gated ion channels: functional 5-HT3 and GABA rho1 receptors lacking the large cytoplasmic M3M4 loopStoichiometric pore mutations of the GABAAR reveal a pattern of hydrogen bonding with picrotoxin.The insecticide fipronil and its metabolite fipronil sulphone inhibit the rat alpha1beta2gamma2L GABA(A) receptor.5-tert-Butyl-2-(4'-[18F]fluoropropynylphenyl)-1,3-dithiane oxides: potential new GABA A receptor radioligandsSynergistic and compensatory effects of two point mutations conferring target-site resistance to fipronil in the insect GABA receptor RDL.Spontaneous mobility of GABAA receptor M2 extracellular half relative to noncompetitive antagonist action.Probing structural features and binding mode of 3-arylpyrimidin-2,4-diones within housefly γ-aminobutyric acid (GABA) receptor.Oxidative stress from diverse developmental neurotoxicants: antioxidants protect against lipid peroxidation without preventing cell lossCys-loop receptor channel blockers also block GLIC.Agonist-induced hump current production in heterologously-expressed human alpha4beta2-nicotinic acetylcholine receptors.Closed-state cross-linking of adjacent beta1 subunits in alpha1beta1 GABAa receptors via introduced 6' cysteines.Is fipronil safer than chlorpyrifos? Comparative developmental neurotoxicity modeled in PC12 cells.GABAA receptor open-state conformation determines non-competitive antagonist binding.Agonist- and antagonist-induced conformational changes of loop F and their contributions to the rho1 GABA receptor function.Mechanisms for picrotoxinin and picrotin blocks of alpha2 homomeric glycine receptors.Conserved toxic responses across divergent phylogenetic lineages: a meta-analysis of the neurotoxic effects of RDX among multiple species using toxicogenomics.GABAA receptor subtype selectivity of the proconvulsant rodenticide TETS.Gaba receptor insecticide non-competitive antagonists may bind at allosteric modulator sites.The IUPAC International Congresses of Pesticide Chemistry (1963-2014) and Pest Management Science: a half-century of progress.Analysis of γ-aminobutyric acid (GABA) type A receptor subtypes using isosteric and allosteric ligands.GABAA receptor: Positive and negative allosteric modulators.Concentration-dependent effects of GABA on insensitivity to fipronil in the A2'S mutant RDL GABA receptor from fipronil-resistant Oulema oryzae (Coleoptera: Chrysomelidae).
P2860
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P2860
Structural model for gamma-aminobutyric acid receptor noncompetitive antagonist binding: widely diverse structures fit the same site
description
2006 nî lūn-bûn
@nan
2006 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի մարտին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Structural model for gamma-ami ...... e structures fit the same site
@ast
Structural model for gamma-ami ...... e structures fit the same site
@en
Structural model for gamma-ami ...... e structures fit the same site
@nl
type
label
Structural model for gamma-ami ...... e structures fit the same site
@ast
Structural model for gamma-ami ...... e structures fit the same site
@en
Structural model for gamma-ami ...... e structures fit the same site
@nl
prefLabel
Structural model for gamma-ami ...... e structures fit the same site
@ast
Structural model for gamma-ami ...... e structures fit the same site
@en
Structural model for gamma-ami ...... e structures fit the same site
@nl
P2093
P2860
P356
P1476
Structural model for gamma-ami ...... e structures fit the same site
@en
P2093
John E Casida
Kathleen A Durkin
Ligong Chen
P2860
P304
P356
10.1073/PNAS.0600370103
P407
P577
2006-03-10T00:00:00Z