Bmi1 enhances tumorigenicity and cancer stem cell function in pancreatic adenocarcinoma.
about
Novel therapeutic targets for pancreatic cancerThe Role of miRNAs in the Regulation of Pancreatic Cancer Stem CellsPolycomb Group (PcG) Proteins and Human Cancers: Multifaceted Functions and Therapeutic ImplicationsThe BMI1 inhibitor PTC-209 is a potential compound to halt cellular growth in biliary tract cancer cellsPancreatic Cancer, A Mis-interpreter of the Epigenetic LanguageDownregulation of Bmi1 in breast cancer stem cells suppresses tumor growth and proliferation.Bmi1 regulates self-renewal and epithelial to mesenchymal transition in breast cancer cells through Nanog.Pilot clinical trial of hedgehog pathway inhibitor GDC-0449 (vismodegib) in combination with gemcitabine in patients with metastatic pancreatic adenocarcinoma.Bmi1 drives stem-like properties and is associated with migration, invasion, and poor prognosis in tongue squamous cell carcinoma.A Bmi1-miRNAs cross-talk modulates chemotherapy response to 5-fluorouracil in breast cancer cellsThe crossroads between cancer stem cells and aging.High expression of carbonic anhydrase IX is significantly associated with glandular lesions in gastroesophageal junction and with tumorigenesis markers BMI1, MCM4 and MCM7Bmi1 is required for the initiation of pancreatic cancer through an Ink4a-independent mechanism.Bmi-1: At the crossroads of physiological and pathological biology.Polycomb complex protein BMI-1 promotes invasion and metastasis of pancreatic cancer stem cells by activating PI3K/AKT signaling, an ex vivo, in vitro, and in vivo study.Epigallocatechin-3-gallate targets cancer stem-like cells and enhances 5-fluorouracil chemosensitivity in colorectal cancer.Bmi1 inhibition enhances the sensitivity of pancreatic cancer cells to gemcitabine.Dysregulation of Bmi1 promotes malignant transformation of hepatic progenitor cellsBmi1-positive cells in the lingual epithelium could serve as cancer stem cells in tongue cancer.The roles of FOXM1 in pancreatic stem cells and carcinogenesisThe ZEB1 transcription factor acts in a negative feedback loop with miR200 downstream of Ras and Rb1 to regulate Bmi1 expression.Tumor-Initiating Cells: a criTICal review of isolation approaches and new challenges in targeting strategies.Regulatory variation: an emerging vantage point for cancer biology.The role of polycomb repressive complexes in biliary tract cancer.Context-dependent actions of Polycomb repressors in cancer.Pathobiology of pancreatic cancer: implications on therapy.miR-15a/miR-16 down-regulates BMI1, impacting Ub-H2A mediated DNA repair and breast cancer cell sensitivity to doxorubicinSilencing BMI1 radiosensitizes human breast cancer cells by inducing DNA damage and autophagy.Enhanced SLC34A2 in breast cancer stem cell-like cells induces chemotherapeutic resistance to doxorubicin via SLC34A2-Bmi1-ABCC5 signaling.Small molecule kinase inhibitor LRRK2-IN-1 demonstrates potent activity against colorectal and pancreatic cancer through inhibition of doublecortin-like kinase 1.Effect of shRNA-Mediated Gene Silencing of Bmi-1 Expression on Chemosensitivity of CD44+ Nasopharyngeal Carcinoma Cancer Stem-Like Cells.Profiling the Behavior of Distinct Populations of Head and Neck Cancer Stem Cells.Mitochondrial BMI1 maintains bioenergetic homeostasis in cells.Sonic Hedgehog Signaling in Thyroid Cancer.GUCY2C maintains intestinal LGR5+ stem cells by opposing ER stress.Exosome-mediated breast cancer chemoresistance via miR-155 transfer.Cancer Stem Cells (CSCs) in Drug Resistance and their Therapeutic Implications in Cancer Treatment.Reduced SLC27A2 induces cisplatin resistance in lung cancer stem cells by negatively regulating Bmi1-ABCG2 signaling.Pancreatic Cancer: Molecular Characterization, Clonal Evolution and Cancer Stem Cells.HNF1A is a novel oncogene that regulates human pancreatic cancer stem cell properties
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P2860
Bmi1 enhances tumorigenicity and cancer stem cell function in pancreatic adenocarcinoma.
description
2013 nî lūn-bûn
@nan
2013 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年学术文章
@wuu
2013年学术文章
@zh-cn
2013年学术文章
@zh-hans
2013年学术文章
@zh-my
2013年学术文章
@zh-sg
2013年學術文章
@yue
name
Bmi1 enhances tumorigenicity and cancer stem cell function in pancreatic adenocarcinoma.
@ast
Bmi1 enhances tumorigenicity and cancer stem cell function in pancreatic adenocarcinoma.
@en
Bmi1 enhances tumorigenicity and cancer stem cell function in pancreatic adenocarcinoma.
@nl
type
label
Bmi1 enhances tumorigenicity and cancer stem cell function in pancreatic adenocarcinoma.
@ast
Bmi1 enhances tumorigenicity and cancer stem cell function in pancreatic adenocarcinoma.
@en
Bmi1 enhances tumorigenicity and cancer stem cell function in pancreatic adenocarcinoma.
@nl
prefLabel
Bmi1 enhances tumorigenicity and cancer stem cell function in pancreatic adenocarcinoma.
@ast
Bmi1 enhances tumorigenicity and cancer stem cell function in pancreatic adenocarcinoma.
@en
Bmi1 enhances tumorigenicity and cancer stem cell function in pancreatic adenocarcinoma.
@nl
P2093
P2860
P1433
P1476
Bmi1 enhances tumorigenicity and cancer stem cell function in pancreatic adenocarcinoma.
@en
P2093
Chenwei Li
Cheong Jun Lee
David G Heidt
Diane M Simeone
Erica Proctor
Filip Bednar
Malica Yalamanchili
Meghna Waghray
P2860
P304
P356
10.1371/JOURNAL.PONE.0055820
P407
P577
2013-02-20T00:00:00Z