about
pRb inactivation in mammary cells reveals common mechanisms for tumor initiation and progression in divergent epitheliaTumor transcriptome sequencing reveals allelic expression imbalances associated with copy number alterationsA systematic screen for CDK4/6 substrates links FOXM1 phosphorylation to senescence suppression in cancer cellsPhosphorylation of pRB at Ser612 by Chk1/2 leads to a complex between pRB and E2F-1 after DNA damageNew insights into the mechanisms of green tea catechins in the chemoprevention of prostate cancermiR-16 family induces cell cycle arrest by regulating multiple cell cycle genes.Crystal structure of human CDK4 in complex with a D-type cyclinA comprehensive pathway map of epidermal growth factor receptor signalingEpstein-Barr virus LMP1 blocks p16INK4a-RB pathway by promoting nuclear export of E2F4/5Genomic Changes in Normal Breast Tissue in Women at Normal Risk or at High Risk for Breast CancerTargeting CDK6 in cancer: State of the art and new insightsTargeting cyclin-dependent kinases in human cancers: from small molecules to Peptide inhibitorsThe Mcm2-7 replicative helicase: a promising chemotherapeutic targetDiscovery of a Potential Allosteric Ligand Binding Site in CDK2A Novel Approach to the Discovery of Small-Molecule Ligands of CDK2Fragment-Based Discovery of 7-Azabenzimidazoles as Potent, Highly Selective, and Orally Active CDK4/6 InhibitorsTherapeutic CDK4/6 inhibition in breast cancer: key mechanisms of response and failure.Role of HOXA9 in leukemia: dysregulation, cofactors and essential targetsBrk/Protein tyrosine kinase 6 phosphorylates p27KIP1, regulating the activity of cyclin D-cyclin-dependent kinase 4Human growth hormone-regulated HOXA1 is a human mammary epithelial oncogeneRegulated activating Thr172 phosphorylation of cyclin-dependent kinase 4(CDK4): its relationship with cyclins and CDK "inhibitors"The H3K36 demethylase Jhdm1b/Kdm2b regulates cell proliferation and senescence through p15(Ink4b)A novel muscarinic antagonist R2HBJJ inhibits non-small cell lung cancer cell growth and arrests the cell cycle in G0/G1Pterostilbene simultaneously induced G0/G1-phase arrest and MAPK-mediated mitochondrial-derived apoptosis in human acute myeloid leukemia cell linesSnail blocks the cell cycle and confers resistance to cell deathQuiescence of adult oligodendrocyte precursor cells requires thyroid hormone and hypoxia to activate Runx1.Discovery of genes implicated in whirling disease infection and resistance in rainbow trout using genome-wide expression profiling.A Phase I Study of the Cyclin-Dependent Kinase 4/6 Inhibitor Ribociclib (LEE011) in Patients with Advanced Solid Tumors and LymphomasConstruction and clarification of dynamic gene regulatory network of cancer cell cycle via microarray data.The identification of unique serum proteins of HIV-1 latently infected long-term non-progressor patients.C-terminal binding protein-2 promotes cell proliferation and migration in breast cancer via suppression of p16INK4A.Targeting the cyclin D-cyclin-dependent kinase (CDK) 4/6-retinoblastoma pathway with selective CDK 4/6 inhibitors in hormone receptor-positive breast cancer: rationale, current status, and future directionsGenomic and epigenetic instability in colorectal cancer pathogenesis.Circadian variation in expression of G1 phase cyclins D1 and E and cyclin-dependent kinase inhibitors p16 and p21 in human bowel mucosaAlterations in RD(INK4/ARF) -mediated en bloc regulation of the INK4-ARF locus in human squamous cell carcinoma of the head and neck.C/EBPα is an essential collaborator in Hoxa9/Meis1-mediated leukemogenesisMultiplicity: an organizing principle for cancers and somatic mutations.Structure-based discovery of the first allosteric inhibitors of cyclin-dependent kinase 2.E2F1-mediated upregulation of p19INK4d determines its periodic expression during cell cycle and regulates cellular proliferation.p16( INK4a) positively regulates cyclin D1 and E2F1 through negative control of AUF1.
P2860
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P2860
description
2002 nî lūn-bûn
@nan
2002 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի մարտին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Cyclin D-dependent kinases, INK4 inhibitors and cancer.
@ast
Cyclin D-dependent kinases, INK4 inhibitors and cancer.
@en
Cyclin D-dependent kinases, INK4 inhibitors and cancer.
@nl
type
label
Cyclin D-dependent kinases, INK4 inhibitors and cancer.
@ast
Cyclin D-dependent kinases, INK4 inhibitors and cancer.
@en
Cyclin D-dependent kinases, INK4 inhibitors and cancer.
@nl
prefLabel
Cyclin D-dependent kinases, INK4 inhibitors and cancer.
@ast
Cyclin D-dependent kinases, INK4 inhibitors and cancer.
@en
Cyclin D-dependent kinases, INK4 inhibitors and cancer.
@nl
P1476
Cyclin D-dependent kinases, INK4 inhibitors and cancer.
@en
P2093
Mariano Barbacid
Sagrario Ortega
P356
10.1016/S0304-419X(02)00037-9
P407
P577
2002-03-01T00:00:00Z