Fragment-Based Discovery of 7-Azabenzimidazoles as Potent, Highly Selective, and Orally Active CDK4/6 Inhibitors
about
Targeting CDK6 in cancer: State of the art and new insightsEmerging therapies for breast cancerAntitumour potential of BPT: a dual inhibitor of cdk4 and tubulin polymerizationPalbociclib can overcome mutations in cyclin dependent kinase 6 that break hydrogen bonds between the drug and the protein.Recent progress of cyclin-dependent kinase inhibitors as potential anticancer agents.Quantitative Relationships Between the Cytotoxicity of Flavonoids on the Human Breast Cancer Stem-Like Cells MCF7-SC and Their Structural Properties.CDK1 structures reveal conserved and unique features of the essential cell cycle CDK.
P2860
Q26796499-EB62A29C-1158-4CB2-B12D-5DDA6FACF57BQ33617949-9F150758-3137-4D55-A504-A29C6E1EE173Q36347006-ABF801B9-07B3-4D1B-AEDA-F1ECEC7787E1Q37723172-1A87B52F-A35F-4268-BFBE-8616AC50C5F4Q38806786-7F090F00-73EF-46A4-97E2-D3B008DD2877Q38920671-61D9B6B4-02E0-43FC-A2F8-BB90C4A4E12FQ40030976-E13F2966-47C0-411A-8341-7C0C5C126AF8
P2860
Fragment-Based Discovery of 7-Azabenzimidazoles as Potent, Highly Selective, and Orally Active CDK4/6 Inhibitors
description
2012 nî lūn-bûn
@nan
2012 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
name
Fragment-Based Discovery of 7- ...... rally Active CDK4/6 Inhibitors
@ast
Fragment-Based Discovery of 7- ...... rally Active CDK4/6 Inhibitors
@en
Fragment-Based Discovery of 7- ...... rally Active CDK4/6 Inhibitors
@nl
type
label
Fragment-Based Discovery of 7- ...... rally Active CDK4/6 Inhibitors
@ast
Fragment-Based Discovery of 7- ...... rally Active CDK4/6 Inhibitors
@en
Fragment-Based Discovery of 7- ...... rally Active CDK4/6 Inhibitors
@nl
prefLabel
Fragment-Based Discovery of 7- ...... rally Active CDK4/6 Inhibitors
@ast
Fragment-Based Discovery of 7- ...... rally Active CDK4/6 Inhibitors
@en
Fragment-Based Discovery of 7- ...... rally Active CDK4/6 Inhibitors
@nl
P2093
P2860
P356
P1476
Fragment-Based Discovery of 7- ...... rally Active CDK4/6 Inhibitors
@en
P2093
Bharat Lagu
Christine Hiu-Tung Chen
Christopher Brain
Claudio Dagostin
David C Rees
Deborah J Davis
Glyn Williams
Hayley Angove
P2860
P304
P356
10.1021/ML200241A
P577
2012-05-17T00:00:00Z