Mitochondrial fission and cristae disruption increase the response of cell models of Huntington's disease to apoptotic stimuli. - Wikidata - awgldk - TriplyDB

Mitochondrial fission and cristae disruption increase the response of cell models of Huntington's disease to apoptotic stimuli.

Mitochondrial fission and cristae disruption increase the response of cell models of Huntington's disease to apoptotic stimuli.

http://www.wikidata.org/entity/Q34605764

about

Structural insights into oligomerization and mitochondrial remodelling of dynamin 1-like protein Defining the role of the Bcl-2 family proteins in Huntington's disease Physiological and pathological significance of dynamin-related protein 1 (drp1)-dependent mitochondrial fission in the nervous system Mitochondrial morphology-emerging role in bioenergetics Metabolic disturbances in diseases with neurological involvement PGC-1α, mitochondrial dysfunction, and Huntington's disease Impaired mitochondrial dynamics and Nrf2 signaling contribute to compromised responses to oxidative stress in striatal cells expressing full-length mutant huntingtin Huntington's disease induced cardiac amyloidosis is reversed by modulating protein folding and oxidative stress pathways in the Drosophila heart Shaping the role of mitochondria in the pathogenesis of Huntington's disease Mitochondrial dysfunction in neurodegenerative diseases Inhibition of mitochondrial protein import by mutant huntingtin Mitochondrial lipids in neurodegeneration Bax activation initiates the assembly of a multimeric catalyst that facilitates Bax pore formation in mitochondrial outer membranes Mitochondria: in sickness and in health During autophagy mitochondria elongate, are spared from degradation and sustain cell viability.The HIV Protein gp120 Alters Mitochondrial Dynamics in Neurons.Crucial role of calbindin-D28k in the pathogenesis of Alzheimer's disease mouse model.Increased mitochondrial fission and neuronal dysfunction in Huntington's disease: implications for molecular inhibitors of excessive mitochondrial fission Altered Ca(2+) signaling in skeletal muscle fibers of the R6/2 mouse, a model of Huntington's disease Abnormal mitochondrial dynamics, mitochondrial loss and mutant huntingtin oligomers in Huntington's disease: implications for selective neuronal damage.Molecular strategies for targeting antioxidants to mitochondria: therapeutic implications.Mitochondrial translocation and interaction of cofilin and Drp1 are required for erucin-induced mitochondrial fission and apoptosis.Neurodegenerative processes in Huntington's disease.Implications of mitochondrial dynamics on neurodegeneration and on hypothalamic dysfunction.Calcium Handling by Endoplasmic Reticulum and Mitochondria in a Cell Model of Huntington's Disease.Oxidative metabolism in YAC128 mouse model of Huntington's disease.Mitochondrial dynamics in cancer and neurodegenerative and neuroinflammatory diseases.Mitochondrial Ca(2+) and neurodegeneration Mitochondria: the next (neurode)generation Novel Metabolic Abnormalities in the Tricarboxylic Acid Cycle in Peripheral Cells From Huntington's Disease Patients Polyglutamine Tract Expansion Increases S-Nitrosylation of Huntingtin and Ataxin-1.PINK1-induced mitophagy promotes neuroprotection in Huntington's disease Altered Mitochondrial Dynamics and TBI Pathophysiology.Synaptic dysfunction, memory deficits and hippocampal atrophy due to ablation of mitochondrial fission in adult forebrain neurons Mitochondria-targeted molecules MitoQ and SS31 reduce mutant huntingtin-induced mitochondrial toxicity and synaptic damage in Huntington's disease.S-nitrosylation of dynamin-related protein 1 mediates mutant huntingtin-induced mitochondrial fragmentation and neuronal injury in Huntington's disease.Mitochondrial cristae shape determines respiratory chain supercomplexes assembly and respiratory efficiency Dynamin assembly strategies and adaptor proteins in mitochondrial fission.Enhanced mitochondrial biogenesis ameliorates disease phenotype in a full-length mouse model of Huntington's disease.Inhibition of mitochondrial fragmentation diminishes Huntington's disease-associated neurodegeneration.

P2860

Q24338467-D84E8DFA-5E7F-440F-BF3E-A0EF4A0E8543 Q26822846-93134687-64E1-4406-A889-BA22D0A30314 Q26851430-09610690-6581-4350-8994-CC0794213576 Q26852770-8D8E1D91-0411-45B7-9ACF-E9AD3E05F494 Q26999015-50AA8644-2B73-48CB-A709-FDC49B6248AE Q27001671-748DE1A8-28C0-44D6-8A60-F2219012107C Q27312215-2384E781-FA57-475B-921C-D1994373DE5A Q27318284-98CE9BEA-FED7-40D9-8EA8-29CAD8D77AD5 Q28384036-C668C801-022E-475D-B662-4FB25715525D Q28387647-CA4C637B-276A-49D1-9B65-9B55A03A3276 Q28394803-9CE79225-4EC6-40E1-9FE2-E6D4EB3A23E4 Q28397548-05BA6DCC-EB9A-4E0B-BB08-BD04265148B4 Q28483986-C1DDE9F6-D1D7-4268-8E8D-0BF9BF0E8D21 Q29614825-10C769DB-97C7-4018-84C2-2932FF9D18EB Q29616569-C94D6C2D-3BB6-46BB-BC73-649DA404117F Q30738175-1E28CED9-6C72-463A-9BBF-20F8F68B5952 Q34153507-9BB2F08F-B8DA-4C88-A6BF-EEE999EAD185 Q34313991-1E581654-7F6A-4382-BFBD-6A22D0DE5ACD Q34409630-74E0DEA0-33C6-4505-9CD1-8476B354AC92 Q34627072-420EA08D-9685-47CA-894E-0127C175403A Q35148462-F501F04E-4EC9-4031-B3AC-3795F7772A9A Q35176451-640791DA-8C0B-49F4-9710-C2372383CF30 Q35572092-18B42314-87BE-4301-A834-DE7E838CDE2E Q35708874-F77F46DC-2E2B-4ECF-8CB7-93EA9978691E Q35906784-F71A4219-4285-4E40-AB42-B191FD7AC762 Q35924062-4E6C7E6A-D193-45F6-951E-C20ED5891471 Q36082495-7C21CE00-2C99-425E-836F-4DE7F8117F86 Q36095330-55956816-CC7C-43B9-B1A5-A88A1DCF18EE Q36124905-116A077B-B2B8-4665-A968-AB1080589128 Q36127832-5DE5AEF2-A6C1-4249-81EC-6D590767C4ED Q36141277-874EF7FC-5F0C-466D-948D-115A9AFA1D5D Q36347184-82478E25-EF6D-4FA3-8BDB-D1FEA42C3FE1 Q36740195-9501F658-0F97-4613-9B6A-4F00C8FD90B3 Q36751251-F55556B1-5A5B-446E-8573-7A393AC4C9DB Q37178581-511AB56D-D2EA-4C71-A3D7-1E96F5599EA5 Q37204122-01680693-F598-492B-A0DE-18328675AC12 Q37215027-D2B0EB50-3FD9-49EE-9E3F-AA5BA44D7F2C Q37320518-48D3F3A5-9567-466F-A309-707AEB270833 Q37368003-0E68B1DC-AC9F-474F-8D7D-23207682AACB Q37384081-B7DE1365-ACB6-47D9-A9CE-B197A99EE2EF

P2860

Mitochondrial fission and cristae disruption increase the response of cell models of Huntington's disease to apoptotic stimuli.

http://www.wikidata.org/entity/Q34605764

description

2010 nî lūn-bûn

@nan

2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Mitochondrial fission and cris ...... disease to apoptotic stimuli.

@ast

Mitochondrial fission and cris ...... disease to apoptotic stimuli.

@en

Mitochondrial fission and cris ...... disease to apoptotic stimuli.

@nl

type

label

Mitochondrial fission and cris ...... disease to apoptotic stimuli.

@ast

Mitochondrial fission and cris ...... disease to apoptotic stimuli.

@en

Mitochondrial fission and cris ...... disease to apoptotic stimuli.

@nl

prefLabel

Mitochondrial fission and cris ...... disease to apoptotic stimuli.

@ast

Mitochondrial fission and cris ...... disease to apoptotic stimuli.

@en

Mitochondrial fission and cris ...... disease to apoptotic stimuli.

@nl

P1433

Q34605764-79E13C83-A2E6-4B3B-A156-09C08C74281E

P1476

Q34605764-0817C6E2-DEF7-41A4-ADBA-4C27089CC769

P2093

Q34605764-BEE93E47-7856-464C-8EE1-F774DE0A03E3

Q34605764-BF424D45-DF6D-4F79-8AC1-697A3E61B451

Q34605764-CF4B9C8A-A023-4F83-B365-F6F85F23C32F

Q34605764-EA35D82A-AFB4-4CF4-B8E5-EFA8BF26E4A3

Q34605764-F24F4331-BFB7-4BB0-B67C-560EFCC4E845

P2860

Q34605764-0CBDDE9C-AAA7-417A-84A6-14B359342FB4

Q34605764-0CCF7F38-20CB-4239-9EEF-354887A6B7A7

Q34605764-0E8E3A97-330D-4650-96CE-77425514527B

Q34605764-108166BE-0816-4320-A451-078BFF4B7374

Q34605764-15DF98C6-87F2-488D-B31C-4EADB67CDEAB

Q34605764-221A5B76-4F2C-4FD9-9590-99FB7611817E

Q34605764-2577CDF4-93EB-4D0E-AB8C-BC1F7208752B

Q34605764-284CB6EB-63F2-4FBD-B208-ECA8FC118D43

Q34605764-29F8F456-D6F4-42D3-88D9-7B5FD4743A15

Q34605764-2B252847-E7A2-4D67-802D-B7A45E2E5534

P304

Q34605764-535D2219-7740-43F8-905A-ECBD48EF8620

P31

Q34605764-EF6F8A3F-468D-4D35-A9ED-7D712BB38BDC

P356

Q34605764-06814AC5-5B68-4FBF-9183-A7470557C162

P433

Q34605764-C1C5DC19-4B4E-4DD5-80E0-918B8F6A14C5

P478

Q34605764-1C5DE7A5-3960-42BC-84EC-4038D8B006AD

P50

Q34605764-069CCF1A-5ADE-4329-B15B-3EE6926C1C26

Q34605764-7A5BD9C4-3BC1-4430-9A94-1C27288864D2

Q34605764-A329D2A3-EB62-4E81-9314-DE8E00955ED8

Q34605764-C57B4FE1-7824-4A58-9467-25B8791E5DED

Q34605764-D1CC9F77-2909-40FC-9B9F-B8F939283018

P577

Q34605764-8F348857-4ED4-4779-973B-86C529111363

P5875

Q34605764-0F51A388-7A6F-4EAC-91EA-3350FC6165D9

P698

Q34605764-37ED94BA-A6F5-4B8C-B8C1-812B2F511813

P921

Q34605764-32133407-6DFB-4704-A7A8-C4D2EC31FB9A

Q34605764-D27E34F5-E4FC-4D0F-9D53-3CF7265983D3

P932

Q34605764-D0E7DC08-63B0-46EC-A059-BEDDA57C77C9

P356

P1433

EMBO Molecular Medicine

P1476

Mitochondrial fission and cris ...... disease to apoptotic stimuli.

@en

P2093

Dmitri Lim

http://www.w3.org/2001/XMLSchema#string

Gennady Ermak

http://www.w3.org/2001/XMLSchema#string

Kelvin J A Davies

http://www.w3.org/2001/XMLSchema#string

Roman Hudec

http://www.w3.org/2001/XMLSchema#string

Veronica Costa

http://www.w3.org/2001/XMLSchema#string

P2860

tBID, a membrane-targeted death ligand, oligomerizes BAK to release cytochrome c

Huntingtin is a cytoplasmic protein associated with vesicles in human and rat brain neurons

Dephosphorylation by calcineurin regulates translocation of Drp1 to mitochondria

Endoplasmic reticulum BIK initiates DRP1-regulated remodelling of mitochondrial cristae during apoptosis.

OPA1 requires mitofusin 1 to promote mitochondrial fusion

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

Cell death: critical control points

OPA1 controls apoptotic cristae remodeling independently from mitochondrial fusion

Mitochondrial rhomboid PARL regulates cytochrome c release during apoptosis via OPA1-dependent cristae remodeling

Increased apoptosis and early embryonic lethality in mice nullizygous for the Huntington's disease gene homologue

P304

490-503

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1002/EMMM.201000102

http://www.w3.org/2001/XMLSchema#string

P433

12

http://www.w3.org/2001/XMLSchema#string

P478

2

http://www.w3.org/2001/XMLSchema#string

P50

Ernesto Carafoli

Marta Giacomello

Raffaele Lopreiato

P577

2010-12-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

47743880

http://www.w3.org/2001/XMLSchema#string

P698

21069748

http://www.w3.org/2001/XMLSchema#string

P921

apoptotic process

Huntington disease

P932

3044888

http://www.w3.org/2001/XMLSchema#string