Structure, mechanism and catalytic duality of thiamine-dependent enzymes.
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Riboswitch effectors as protein enzyme cofactorsProbing the Active Center of Benzaldehyde Lyase with Substitutions and the Pseudosubstrate Analogue Benzoylphosphonic Acid Methyl Ester †Specificity and Reactivity in Menaquinone Biosynthesis: The Structure of Escherichia coli MenD (2-Succinyl-5-Enolpyruvyl-6-Hydroxy-3-Cyclohexadiene-1-Carboxylate Synthase)Snapshots of Catalysis in the E1 Subunit of the Pyruvate Dehydrogenase Multienzyme ComplexExtended reaction scope of thiamine diphosphate dependent cyclohexane-1,2-dione hydrolase: from C-C bond cleavage to C-C bond ligationIdentification of inhibitors against Mycobacterium tuberculosis thiamin phosphate synthase, an important target for the development of anti-TB drugsThe chemical versatility of RNAVitamin B1 in marine sediments: pore water concentration gradient drives benthic flux with potential biological implications.The Thiamine diphosphate dependent Enzyme Engineering Database: a tool for the systematic analysis of sequence and structure relations.Folate and thiamine transporters mediated by facilitative carriers (SLC19A1-3 and SLC46A1) and folate receptors.Kinetic and spectroscopic evidence of negative cooperativity in the action of lysine 2,3-aminomutase.Comparative genomics of nucleotide metabolism: a tour to the past of the three cellular domains of life.α,β-Unsaturated acyl azoliums from N-heterocyclic carbene catalyzed reactions: observation and mechanistic investigation.1-Deoxy-D-xylulose 5-phosphate synthase catalyzes a novel random sequential mechanismActhi, a thiazole biosynthesis enzyme, is essential for thiamine biosynthesis and CPC production in Acremonium chrysogenum.Experimental observation of thiamin diphosphate-bound intermediates on enzymes and mechanistic information derived from these observationsMechanistic binding insights for 1-deoxy-D-Xylulose-5-Phosphate synthase, the enzyme catalyzing the first reaction of isoprenoid biosynthesis in the malaria-causing protists, Plasmodium falciparum and Plasmodium vivax.Randomized, Double-Blind, Placebo-Controlled Trial of Thiamine as a Metabolic Resuscitator in Septic Shock: A Pilot StudyDXP synthase-catalyzed C-N bond formation: nitroso substrate specificity studies guide selective inhibitor design.Reducing milking frequency during nutrient restriction has no effect on the hepatic transcriptome of lactating dairy cattle.Reaction mechanisms of thiamin diphosphate enzymes: defining states of ionization and tautomerization of the cofactor at individual steps.The Specific Roles of Vitamins in the Regulation of Immunosurveillance and Maintenance of Immunologic Homeostasis in the Gut.Influence of vitamin B auxotrophy on nitrogen metabolism in eukaryotic phytoplanktonUsing site-saturation mutagenesis to explore mechanism and substrate specificity in thiamin diphosphate-dependent enzymes.Catalysis in Enzymatic Decarboxylations: Comparison of Selected Cofactor-dependent and Cofactor-independent Examples.Engineering stereoselectivity of ThDP-dependent enzymes.Plant amino acid-derived vitamins: biosynthesis and function.DXS as a target for structure-based drug design.Metabolic changes during B cell differentiation for the production of intestinal IgA antibody.Validation of a homology model of Mycobacterium tuberculosis DXS: rationalization of observed activities of thiamine derivatives as potent inhibitors of two orthologues of DXS.The upregulation of thiamine (vitamin B1) biosynthesis in Arabidopsis thaliana seedlings under salt and osmotic stress conditions is mediated by abscisic acid at the early stages of this stress response.Use of plankton-derived vitamin B1 precursors, especially thiazole-related precursor, by key marine picoeukaryotic phytoplankton.Thiamin Diphosphate Activation in 1-Deoxy-d-xylulose 5-Phosphate Synthase: Insights into the Mechanism and Underlying Intermolecular InteractionsStructural and electrostatic asymmetry at the active site in typical and atypical peroxiredoxin dimers.Engineering homooligomeric proteins to detect weak intersite allosteric communication: aminotransferases, a case study.Crystal structure of a ring-cleaving cyclohexane-1,2-dione hydrolase, a novel member of the thiamine diphosphate enzyme family.Orchestration of thiamin biosynthesis and central metabolism by combined action of the thiamin pyrophosphate riboswitch and the circadian clock in Arabidopsis.Protein families reflect the metabolic diversity of organisms and provide support for functional prediction.Vitamin B1 diversity and characterization of biosynthesis genes in cassava.Decreased TK activity alters growth, yield and tolerance to low temperature and low light intensity in transgenic cucumber plants.
P2860
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P2860
Structure, mechanism and catalytic duality of thiamine-dependent enzymes.
description
2007 nî lūn-bûn
@nan
2007 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Structure, mechanism and catalytic duality of thiamine-dependent enzymes.
@ast
Structure, mechanism and catalytic duality of thiamine-dependent enzymes.
@en
Structure, mechanism and catalytic duality of thiamine-dependent enzymes.
@nl
type
label
Structure, mechanism and catalytic duality of thiamine-dependent enzymes.
@ast
Structure, mechanism and catalytic duality of thiamine-dependent enzymes.
@en
Structure, mechanism and catalytic duality of thiamine-dependent enzymes.
@nl
prefLabel
Structure, mechanism and catalytic duality of thiamine-dependent enzymes.
@ast
Structure, mechanism and catalytic duality of thiamine-dependent enzymes.
@en
Structure, mechanism and catalytic duality of thiamine-dependent enzymes.
@nl
P2093
P1476
Structure, mechanism and catalytic duality of thiamine-dependent enzymes.
@en
P2093
P2888
P304
P356
10.1007/S00018-007-6423-5
P577
2007-04-01T00:00:00Z