about
The Werner syndrome protein is distinguished from the Bloom syndrome protein by its capacity to tightly bind diverse DNA structuresInteraction between the helicases genetically linked to Fanconi anemia group J and Bloom's syndromeSF1 and SF2 helicases: family mattersRoles of Werner syndrome protein in protection of genome integrityRoles of RECQ helicases in recombination based DNA repair, genomic stability and agingDNA mismatch repair: molecular mechanism, cancer, and ageingBLAP18/RMI2, a novel OB-fold-containing protein, is an essential component of the Bloom helicase-double Holliday junction dissolvasomeHuman premature aging, DNA repair and RecQ helicasesStructure of the DNA Repair Helicase Hel308 Reveals DNA Binding and Autoinhibitory DomainsEsc2 and Sgs1 act in functionally distinct branches of the homologous recombination repair pathway in Saccharomyces cerevisiae.Sumoylation of the BLM ortholog, Sgs1, promotes telomere-telomere recombination in budding yeast.Distinct roles of RECQ1 in the maintenance of genomic stability.Altered gene expression in the Werner and Bloom syndromes is associated with sequences having G-quadruplex forming potential.Loss of Blm enhances basal cell carcinoma and rhabdomyosarcoma tumorigenesis in Ptch1+/- mice.Conserved helicase domain of human RecQ4 is required for strand annealing-independent DNA unwinding.Cruciform structures are a common DNA feature important for regulating biological processes.Role of oxidatively induced DNA lesions in human pathogenesisWhen transcription meets recombination: a lesson from the human RECQ protein complexesDNA repair deficiency in neurodegeneration.The mutation spectrum in RECQL4 diseases.The helicase and ATPase activities of RECQL4 are compromised by mutations reported in three human patientsEssential developmental, genomic stability, and tumour suppressor functions of the mouse orthologue of hSSB1/NABP2.Topo IIIalpha and BLM act within the Fanconi anemia pathway in response to DNA-crosslinking agents.Helicase-inactivating mutations as a basis for dominant negative phenotypes.Human RecQL4 helicase plays critical roles in prostate carcinogenesis.Sgs1 truncations induce genome rearrangements but suppress detrimental effects of BLM overexpression in Saccharomyces cerevisiae.Determination of the biochemical properties of full-length human PIF1 ATPase.A conditional mouse model for measuring the frequency of homologous recombination events in vivo in the absence of essential genes.Fanconi anemia and Bloom's syndrome crosstalk through FANCJ-BLM helicase interaction.Lessons learned from UvrD helicase: mechanism for directional movement.Cellular RNA helicases and HIV-1: insights from genome-wide, proteomic, and molecular studiesClinicopathological and prognostic significance of RECQL5 helicase expression in breast cancers.RECQ1 possesses DNA branch migration activity.The fission yeast BLM homolog Rqh1 promotes meiotic recombination.Sensitivity of RECQL4-deficient fibroblasts from Rothmund-Thomson syndrome patients to genotoxic agents.Drosophila homologue of the Rothmund-Thomson syndrome gene: essential function in DNA replication during development.A Comparative Study of G-Quadruplex Unfolding and DNA Reeling Activities of Human RECQ5 HelicaseQuality control of DNA break metabolism: in the 'end', it's a good thing.The RecQ DNA helicases: Jacks-of-all-trades or master-tradesmen?BLM helicase measures DNA unwound before switching strands and hRPA promotes unwinding reinitiation.
P2860
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P2860
description
2007 nî lūn-bûn
@nan
2007 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Molecular genetics of RecQ helicase disorders.
@ast
Molecular genetics of RecQ helicase disorders.
@en
Molecular genetics of RecQ helicase disorders.
@nl
type
label
Molecular genetics of RecQ helicase disorders.
@ast
Molecular genetics of RecQ helicase disorders.
@en
Molecular genetics of RecQ helicase disorders.
@nl
prefLabel
Molecular genetics of RecQ helicase disorders.
@ast
Molecular genetics of RecQ helicase disorders.
@en
Molecular genetics of RecQ helicase disorders.
@nl
P1476
Molecular genetics of RecQ helicase disorders.
@en
P2093
P2888
P304
P356
10.1007/S00018-007-7121-Z
P577
2007-09-01T00:00:00Z