A rapid in vitro method for obtaining RNA accessibility patterns for complementary DNA probes: correlation with an intracellular pattern and known RNA structures
about
Secondary structure prediction and in vitro accessibility of mRNA as tools in the selection of target sites for ribozymesPredicting oligonucleotide affinity to nucleic acid targets.Utilization of tmRNA sequences for bacterial identificationTransfer RNA(Ala) recognizes transfer-messenger RNA with specificity; a functional complex prior to entering the ribosome?Mapping of RNA accessible sites by extension of random oligonucleotide libraries with reverse transcriptase.Determination of optimal sites of antisense oligonucleotide cleavage within TNFalpha mRNA.Mapping of accessible sites for oligonucleotide hybridization on hepatitis delta virus ribozymesmRNA accessible site tagging (MAST): a novel high throughput method for selecting effective antisense oligonucleotidesFast and accurate determination of sites along the FUT2 in vitro transcript that are accessible to antisense oligonucleotides by application of secondary structure predictions and RNase H in combination with MALDI-TOF mass spectrometry.Construction of a directed hammerhead ribozyme library: towards the identification of optimal target sites for antisense-mediated gene inhibition.Complete, gene-specific siRNA libraries: production and expression in mammalian cells.Selection of antisense oligonucleotides based on multiple predicted target mRNA structures.Improvement of RNA secondary structure prediction using RNase H cleavage and randomized oligonucleotides.Thermodynamic and kinetic characterization of antisense oligodeoxynucleotide binding to a structured mRNAVariables and strategies in development of therapeutic post-transcriptional gene silencing agentsAntisense therapy for cancer.Comparative analyses of the secondary structures of synthetic and intracellular yeast MFA2 mRNAs.Therapeutic applications of aptamers.Treatment of malignant gliomas with TGF-beta2 antisense oligonucleotides.Comparative study of DNA enzymes and ribozymes against the same full-length messenger RNA of the vanilloid receptor subtype I.5'-bis-pyrenylated oligonucleotides displaying excimer fluorescence provide sensitive probes of RNA sequence and structure.Identifying ribozyme-accessible sites using NUH triplet-targeting gapmers.Statistical prediction of single-stranded regions in RNA secondary structure and application to predicting effective antisense target sites and beyond.RNA accessibility prediction: a theoretical approach is consistent with experimental studies in cell extracts.Effects of RNA secondary structure on cellular antisense activity.siRNAs target sites selection of ezrin and the influence of RNA interference on ezrin expression and biological characters of osteosarcoma cells.Extending the cleavage rules for the hammerhead ribozyme: mutating adenosine15.1 to inosine15.1 changes the cleavage site specificity from N16.2U16.1H17 to N16.2C16.1H17.Probing alternative foldings of the HIV-1 leader RNA by antisense oligonucleotide scanning arrays.Prediction of antisense oligonucleotide efficacy using aggregate motifs.Ezrin mRNA target site selection for DNAzymes using secondary structure and hybridization thermodynamics.
P2860
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P2860
A rapid in vitro method for obtaining RNA accessibility patterns for complementary DNA probes: correlation with an intracellular pattern and known RNA structures
description
1997 nî lūn-bûn
@nan
1997 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
A rapid in vitro method for ob ...... ttern and known RNA structures
@ast
A rapid in vitro method for ob ...... ttern and known RNA structures
@en
A rapid in vitro method for ob ...... ttern and known RNA structures
@nl
type
label
A rapid in vitro method for ob ...... ttern and known RNA structures
@ast
A rapid in vitro method for ob ...... ttern and known RNA structures
@en
A rapid in vitro method for ob ...... ttern and known RNA structures
@nl
prefLabel
A rapid in vitro method for ob ...... ttern and known RNA structures
@ast
A rapid in vitro method for ob ...... ttern and known RNA structures
@en
A rapid in vitro method for ob ...... ttern and known RNA structures
@nl
P2093
P2860
P356
P1476
A rapid in vitro method for ob ...... ttern and known RNA structures
@en
P2093
J F Atkins
O Matveeva
R F Gesteland
P2860
P304
P356
10.1093/NAR/25.24.5010
P407
P577
1997-12-01T00:00:00Z