Effects of RNA secondary structure on cellular antisense activity. - Wikidata - awgldk - TriplyDB

Effects of RNA secondary structure on cellular antisense activity.

Effects of RNA secondary structure on cellular antisense activity.

http://www.wikidata.org/entity/Q38315200

about

Secondary structure prediction and in vitro accessibility of mRNA as tools in the selection of target sites for ribozymes Improved targeting of miRNA with antisense oligonucleotides Effects of template sequence and secondary structure on DNA-templated reactivity siRNA target site secondary structure predictions using local stable substructures Profiled support vector machines for antisense oligonucleotide efficacy prediction Genome-wide selection of unique and valid oligonucleotides.AOBase: a database for antisense oligonucleotides selection and design.Mapping of RNA accessible sites by extension of random oligonucleotide libraries with reverse transcriptase.Gene knockdown by large circular antisense for high-throughput functional genomics.Selection of antisense oligonucleotides based on multiple predicted target mRNA structures.A structural analysis of in vitro catalytic activities of hammerhead ribozymes.Dynamics of co-transcriptional pre-mRNA folding influences the induction of dystrophin exon skipping by antisense oligonucleotides.Identification of genes involved in liver cancer cell growth using an antisense library of phage genomic DNA.Optimization of a novel biophysical model using large scale in vivo antisense hybridization data displays improved prediction capabilities of structurally accessible RNA regions Thermodynamic and kinetic characterization of antisense oligodeoxynucleotide binding to a structured mRNA Potential therapeutic application of antisense oligonucleotides in the treatment of ocular diseases.Fully modified 2' MOE oligonucleotides redirect polyadenylation Targeting of repeated sequences unique to a gene results in significant increases in antisense oligonucleotide potency.Fine-Tuning of the Fatty Acid Pathway by Synthetic Antisense RNA for Enhanced (2S)-Naringenin Production from l-Tyrosine in Escherichia coli Variables and strategies in development of therapeutic post-transcriptional gene silencing agents Rational design and rapid screening of antisense oligonucleotides for prokaryotic gene modulation.The potential of antisense as a CNS therapeutic.Effect of target secondary structure on RNAi efficiency.Efficient siRNA selection using hybridization thermodynamics.Antisense oligonucleotides: from design to therapeutic application.Fundamental differences in the equilibrium considerations for siRNA and antisense oligodeoxynucleotide design OligoWalk: an online siRNA design tool utilizing hybridization thermodynamics Impact of target mRNA structure on siRNA silencing efficiency: A large-scale study Non-nucleotide Modification of Anti-miRNA Oligonucleotides.5'-bis-pyrenylated oligonucleotides displaying excimer fluorescence provide sensitive probes of RNA sequence and structure.Antisense oligonucleotides selected by hybridisation to scanning arrays are effective reagents in vivo.Statistical prediction of single-stranded regions in RNA secondary structure and application to predicting effective antisense target sites and beyond."Parallel" and "antiparallel tail-clamps" increase the efficiency of triplex formation with structured DNA and RNA targets.Rapid determination of RNA accessible sites by surface plasmon resonance detection of hybridization to DNA arrays.Design of phosphorodiamidate morpholino oligomers (PMOs) for the induction of exon skipping of the human DMD gene.Managing the sequence-specificity of antisense oligonucleotides in drug discovery.Targeting a pre-mRNA structure with bipartite antisense molecules modulates tau alternative splicing.siRNAs target sites selection of ezrin and the influence of RNA interference on ezrin expression and biological characters of osteosarcoma cells.Stabilization of the tau exon 10 stem loop alters pre-mRNA splicing.mRNA fusion constructs serve in a general cell-based assay to profile oligonucleotide activity.

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Effects of RNA secondary structure on cellular antisense activity.

http://www.wikidata.org/entity/Q38315200

description

2000 nî lūn-bûn

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2000年の論文

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2000年論文

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2000年論文

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2000年論文

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2000年論文

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2000年論文

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2000年论文

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2000年论文

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2000年论文

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name

Effects of RNA secondary structure on cellular antisense activity.

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type

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Effects of RNA secondary structure on cellular antisense activity.

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Effects of RNA secondary structure on cellular antisense activity.

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Nucleic Acids Research

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Effects of RNA secondary structure on cellular antisense activity.

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Freier SM

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Vickers TA

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Wyatt JR

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P2860

Coaxial stacking of helixes enhances binding of oligoribonucleotides and improves predictions of RNA folding

Expanded sequence dependence of thermodynamic parameters improves prediction of RNA secondary structure

Selecting effective antisense reagents on combinatorial oligonucleotide arrays

Antisense oligonucleotides suppress B-cell lymphoma growth in a SCID-hu mouse model

On finding all suboptimal foldings of an RNA molecule

Catalysis of RNA cleavage by the Tetrahymena thermophila ribozyme. 1. Kinetic description of the reaction of an RNA substrate complementary to the active site.

Catalysis of RNA cleavage by the Tetrahymena thermophila ribozyme. 2. Kinetic description of the reaction of an RNA substrate that forms a mismatch at the active site.

Single-nucleotide polymorphisms can cause different structural folds of mRNA.

Inhibition of human immunodeficiency virus replication by antisense oligodeoxynucleotides.

Inhibition of endothelial cell adhesion molecule expression with antisense oligonucleotides.

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