Up-regulation of acetyl-CoA carboxylase alpha and fatty acid synthase by human epidermal growth factor receptor 2 at the translational level in breast cancer cells.
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Human breast cancer tissues contain abundant phosphatidylcholine(36∶1) with high stearoyl-CoA desaturase-1 expressionSREBP activity is regulated by mTORC1 and contributes to Akt-dependent cell growthKeap1/Nrf2 pathway in the frontiers of cancer and non-cancer cell metabolismMYC and metabolism on the path to cancerCancer metabolic reprogramming: importance, main features, and potentials for precise targeted anti-cancer therapiesStructure and function of biotin-dependent carboxylasesThe potential of ¹¹C-acetate PET for monitoring the Fatty acid synthesis pathway in TumorsLipid biology of breast cancerMetformin Decouples Phospholipid Metabolism in Breast Cancer CellsBlockade of fatty acid synthase triggers significant apoptosis in mantle cell lymphomaMetabolic genes in cancer: their roles in tumor progression and clinical implicationsIntracellular parasitism with Toxoplasma gondii stimulates mammalian-target-of-rapamycin-dependent host cell growth despite impaired signalling to S6K1 and 4E-BP1.Palmitoylation: a protein S-acylation with implications for breast cancer.Significantly increased monounsaturated lipids relative to polyunsaturated lipids in six types of cancer microenvironment are observed by mass spectrometry imaging.Biochemistry, molecular biology, and pharmacology of fatty acid synthase, an emerging therapeutic target and diagnosis/prognosis marker.The selective target of capsaicin on FASN expression and de novo fatty acid synthesis mediated through ROS generation triggers apoptosis in HepG2 cells.Fatty acid synthase inhibition by amentoflavone suppresses HER2/neu (erbB2) oncogene in SKBR3 human breast cancer cells.Fatty acid synthase phosphorylation: a novel therapeutic target in HER2-overexpressing breast cancer cells.A class of genes in the HER2 regulon that is poised for transcription in breast cancer cell lines and expressed in human breast tumorsGenetic variants in de novo lipogenic pathway genes predict the prognosis of surgically-treated hepatocellular carcinoma.Cancer cells differentially activate and thrive on de novo lipid synthesis pathways in a low-lipid environment.Hypoxia induces a lipogenic cancer cell phenotype via HIF1α-dependent and -independent pathways.Fatty acid synthase as a potential therapeutic target in cancer.Transformation with oncogenic Ras and the simian virus 40 T antigens induces caspase-dependent sensitivity to fatty acid biosynthetic inhibitionA novel inhibitor of fatty acid synthase shows activity against HER2+ breast cancer xenografts and is active in anti-HER2 drug-resistant cell lines.EGFR Signal-Network Reconstruction Demonstrates Metabolic Crosstalk in EMT.Metabolomics in bladder cancer: a systematic review.Repression of endometrial tumor growth by targeting SREBP1 and lipogenesisPalmitate-induced ER stress increases trastuzumab sensitivity in HER2/neu-positive breast cancer cellsDysregulation of fatty acid synthesis and glycolysis in non-Hodgkin lymphoma.Analysis of in vitro ADCC and clinical response to trastuzumab: possible relevance of FcγRIIIA/FcγRIIA gene polymorphisms and HER-2 expression levels on breast cancer cell lines.Dysregulated lipid metabolism in cancer.Profiling the role of mammalian target of rapamycin in the vascular smooth muscle metabolome in pulmonary arterial hypertension.The potential utility of acetyltanshinone IIA in the treatment of HER2-overexpressed breast cancer: Induction of cancer cell death by targeting apoptotic and metabolic signaling pathwaysDifferent fatty acid metabolism effects of (-)-epigallocatechin-3-gallate and C75 in adenocarcinoma lung cancer.G protein-coupled estrogen receptor mediates the up-regulation of fatty acid synthase induced by 17β-estradiol in cancer cells and cancer-associated fibroblasts.Regulation of lipid synthesis by the RNA helicase Mov10 controls Wnt5a production.Carnitine palmitoyltransferase 1A functions to repress FoxO transcription factors to allow cell cycle progression in ovarian cancer.Loss of fatty acid synthase inhibits the "HER2-PI3K/Akt axis" activity and malignant phenotype of Caco-2 cells.De novo fatty-acid synthesis and related pathways as molecular targets for cancer therapy.
P2860
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P2860
Up-regulation of acetyl-CoA carboxylase alpha and fatty acid synthase by human epidermal growth factor receptor 2 at the translational level in breast cancer cells.
description
2007 nî lūn-bûn
@nan
2007 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Up-regulation of acetyl-CoA ca ...... level in breast cancer cells.
@ast
Up-regulation of acetyl-CoA ca ...... level in breast cancer cells.
@en
Up-regulation of acetyl-CoA ca ...... level in breast cancer cells.
@nl
type
label
Up-regulation of acetyl-CoA ca ...... level in breast cancer cells.
@ast
Up-regulation of acetyl-CoA ca ...... level in breast cancer cells.
@en
Up-regulation of acetyl-CoA ca ...... level in breast cancer cells.
@nl
prefLabel
Up-regulation of acetyl-CoA ca ...... level in breast cancer cells.
@ast
Up-regulation of acetyl-CoA ca ...... level in breast cancer cells.
@en
Up-regulation of acetyl-CoA ca ...... level in breast cancer cells.
@nl
P2093
P2860
P356
P1476
Up-regulation of acetyl-CoA ca ...... l level in breast cancer cells
@en
P2093
Byeong-Woo Park
Jong-Seok Moon
Min-Young Lee
Sahng Wook Park
Sarah Yoon
Yoo-Kyung Koh
P2860
P304
26122-26131
P356
10.1074/JBC.M702854200
P407
P577
2007-07-13T00:00:00Z