Separate respiratory phenotypes in methyl-CpG-binding protein 2 (Mecp2) deficient mice.
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MeCP2 deficiency results in robust Rett-like behavioural and motor deficits in male and female ratsFemale Mecp2(+/-) mice display robust behavioral deficits on two different genetic backgrounds providing a framework for pre-clinical studies.Brain activity mapping in Mecp2 mutant mice reveals functional deficits in forebrain circuits, including key nodes in the default mode network, that are reversed with ketamine treatment.Preclinical research in Rett syndrome: setting the foundation for translational success.Effect of Sarizotan, a 5-HT1a and D2-like receptor agonist, on respiration in three mouse models of Rett syndromeRespiratory phenotypes are distinctly affected in mice with common Rett syndrome mutations MeCP2 T158A and R168X.β2-Adrenergic receptor agonist ameliorates phenotypes and corrects microRNA-mediated IGF1 deficits in a mouse model of Rett syndromeCorrection of respiratory disorders in a mouse model of Rett syndrome.7,8-dihydroxyflavone exhibits therapeutic efficacy in a mouse model of Rett syndromeA selective 5-HT1a receptor agonist improves respiration in a mouse model of Rett syndrome.Characterization of the MeCP2R168X knockin mouse model for Rett syndrome.Habituation without NMDA Receptor-Dependent Desensitization of Hering-Breuer Apnea Reflex in a Mecp2 Mutant Mouse Model of Rett SyndromeGenotype-specific effects of Mecp2 loss-of-function on morphology of Layer V pyramidal neurons in heterozygous female Rett syndrome model mice.Acute intermittent hypoxia-induced expression of brain-derived neurotrophic factor is disrupted in the brainstem of methyl-CpG-binding protein 2 null mice.Impaired CO2 sensitivity of astrocytes in a mouse model of Rett syndrome.Loss of MeCP2 Causes Urological Dysfunction and Contributes to Death by Kidney Failure in Mouse Models of Rett Syndrome.Increasing brain serotonin corrects CO2 chemosensitivity in methyl-CpG-binding protein 2 (Mecp2)-deficient miceRett syndrome: recent research progress.Neural control of breathing: insights from genetic mouse models.Breathing dysfunction in Rett syndrome: understanding epigenetic regulation of the respiratory networkBreathing disorders in Rett syndrome: progressive neurochemical dysfunction in the respiratory network after birthLong-term home cage activity scans reveal lowered exploratory behaviour in symptomatic female Rett mice.Inflammatory lung disease in Rett syndrome.The ventilatory response to hypoxia in mammals: mechanisms, measurement, and analysis.Genetic diseases: congenital central hypoventilation, Rett, and Prader-Willi syndromes.Neurotrophic factors in development and regulation of respiratory control.Embryonic hindbrain patterning genes delineate distinct cardio-respiratory and metabolic homeostatic populations in the adultBreathing abnormalities in animal models of Rett syndrome a female neurogenetic disorder.Pathogenesis of Lethal Aspiration Pneumonia in Mecp2-null Mouse Model for Rett SyndromeEnhanced hypoxia susceptibility in hippocampal slices from a mouse model of rett syndrome.Exclusive expression of MeCP2 in the nervous system distinguishes between brain and peripheral Rett syndrome-like phenotypes.Conditional depletion of methyl-CpG-binding protein 2 in astrocytes depresses the hypercapnic ventilatory response in mice.Effect of inspired oxygen on periodic breathing in methy-CpG-binding protein 2 (Mecp2) deficient mice.
P2860
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P2860
Separate respiratory phenotypes in methyl-CpG-binding protein 2 (Mecp2) deficient mice.
description
2006 nî lūn-bûn
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2006 թուականի Ապրիլին հրատարակուած գիտական յօդուած
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2006 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2006年の論文
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2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Separate respiratory phenotypes in methyl-CpG-binding protein 2 (Mecp2) deficient mice.
@ast
Separate respiratory phenotypes in methyl-CpG-binding protein 2 (Mecp2) deficient mice.
@en
Separate respiratory phenotypes in methyl-CpG-binding protein 2
@nl
type
label
Separate respiratory phenotypes in methyl-CpG-binding protein 2 (Mecp2) deficient mice.
@ast
Separate respiratory phenotypes in methyl-CpG-binding protein 2 (Mecp2) deficient mice.
@en
Separate respiratory phenotypes in methyl-CpG-binding protein 2
@nl
prefLabel
Separate respiratory phenotypes in methyl-CpG-binding protein 2 (Mecp2) deficient mice.
@ast
Separate respiratory phenotypes in methyl-CpG-binding protein 2 (Mecp2) deficient mice.
@en
Separate respiratory phenotypes in methyl-CpG-binding protein 2
@nl
P2860
P1433
P1476
Separate respiratory phenotypes in methyl-CpG-binding protein 2 (Mecp2) deficient mice.
@en
P2093
John M Bissonnette
Sharon J Knopp
P2860
P304
P356
10.1203/01.PDR.0000203157.31924.4A
P407
P433
P577
2006-04-01T00:00:00Z
P5875
P6179
1007383055