Expanded repertoire of AAV vector serotypes mediate unique patterns of transduction in mouse brain.
about
Biology of adeno-associated viral vectors in the central nervous systemThe prospect of molecular therapy for Angelman syndrome and other monogenic neurologic disorders3D Imaging of Axons in Transparent Spinal Cords from Rodents and Nonhuman Primates(,.)Gene therapy for metachromatic leukodystrophy.Targeted delivery of self-complementary adeno-associated virus serotype 9 to the brain, using magnetic resonance imaging-guided focused ultrasoundSialic acid deposition impairs the utility of AAV9, but not peptide-modified AAVs for brain gene therapy in a mouse model of lysosomal storage diseaseViral transduction of the neonatal brain delivers controllable genetic mosaicism for visualising and manipulating neuronal circuits in vivo.Long-distance axonal transport of AAV9 is driven by dynein and kinesin-2 and is trafficked in a highly motile Rab7-positive compartment.Treatment of congenital neurotransmitter deficiencies by intracerebral ventricular injection of an adeno-associated virus serotype 9 vector.Adenosine kinase, glutamine synthetase and EAAT2 as gene therapy targets for temporal lobe epilepsy.Redirecting N-acetylaspartate metabolism in the central nervous system normalizes myelination and rescues Canavan disease.Directed evolution of adeno-associated virus for glioma cell transductionRetrograde gene delivery to hypoglossal motoneurons using adeno-associated virus serotype 9.Therapeutic benefit of lentiviral-mediated neonatal intracerebral gene therapy in a mouse model of globoid cell leukodystrophyEfficient gene delivery and selective transduction of glial cells in the mammalian brain by AAV serotypes isolated from nonhuman primates.Comparative transduction efficiency of AAV vector serotypes 1-6 in the substantia nigra and striatum of the primate brain.Differential transduction following basal ganglia administration of distinct pseudotyped AAV capsid serotypes in nonhuman primatesTwo-photon imaging of calcium in virally transfected striate cortical neurons of behaving monkeyGlobal CNS transduction of adult mice by intravenously delivered rAAVrh.8 and rAAVrh.10 and nonhuman primates by rAAVrh.10Viral vectors for neurotrophic factor delivery: a gene therapy approach for neurodegenerative diseases of the CNSGene transfer to the CNS using recombinant adeno-associated virusAdeno-associated virus serotypes 1, 8, and 9 share conserved mechanisms for anterograde and retrograde axonal transport.Controlling brain tumor growth by intraventricular administration of an AAV vector encoding IFN-beta.RH10 provides superior transgene expression in mice when compared with natural AAV serotypes for neonatal gene therapy.Specific disruption of astrocytic Ca2+ signaling pathway in vivo by adeno-associated viral transduction.Intracerebroventricular viral injection of the neonatal mouse brain for persistent and widespread neuronal transduction.Phosphorylation dynamics regulate Hsp27-mediated rescue of neuronal plasticity deficits in tau transgenic mice.Capsid serotype and timing of injection determines AAV transduction in the neonatal mice brain.Brain BLAQ: Post-hoc thick-section histochemistry for localizing optogenetic constructs in neurons and their distal terminalsPreclinical differences of intravascular AAV9 delivery to neurons and glia: a comparative study of adult mice and nonhuman primatesImproving single injection CSF delivery of AAV9-mediated gene therapy for SMA: a dose-response study in mice and nonhuman primates.Gene therapy for the nervous system: challenges and new strategies.Widespread and efficient transduction of spinal cord and brain following neonatal AAV injection and potential disease modifying effect in ALS mice.Bilateral single-site intracerebral injection of a nonpathogenic herpes simplex virus-1 vector decreases anxiogenic behavior in MPS VII mice.Making the White Matter Matters: Progress in Understanding Canavan's Disease and Therapeutic Interventions Through Eight Decades.Controlling AAV Tropism in the Nervous System with Natural and Engineered Capsids.A review of gene therapy in canine and feline models of lysosomal storage disorders.Correction of brain oligodendrocytes by AAVrh.10 intracerebral gene therapy in metachromatic leukodystrophy mice.Use of Adeno-Associated and Herpes Simplex Viral Vectors for In Vivo Neuronal Expression in Mice.A gustotopic map of taste qualities in the mammalian brain
P2860
Q21129328-8A3CFAF5-9E5A-4E7B-9A69-9EC5A04AB063Q27021312-262CF69F-6FC6-47EE-9718-28DA6FDAB34FQ28547475-392E9814-DF8B-4AF7-9126-05D3F007C5A7Q30357745-59DB06A7-00AC-453B-B113-14A9AE586A3AQ30447740-DF3706D9-2D4D-45F5-840D-2639BEF96A6EQ30519560-03BA0256-CD8C-45E3-A70E-12B385EE3A10Q30538923-7262846D-B013-4021-ADAC-0D9CA8534A25Q30573520-032A105A-9146-4430-8F8F-5370457F90C3Q30574128-01D5F64F-817A-47E7-BDB3-6919C8CBF419Q30605561-9AE0CF40-A86C-4C33-B85B-2F849613F731Q30837462-E731B955-BBFE-4011-AB44-9306D29EB53AQ33484220-61169355-FD0B-4877-81D6-4E9C1C153108Q33586940-4E42759C-E704-4F5F-B626-85748DDC25FAQ33649318-BE6AC3C8-A9D8-427C-AAC1-63C620FF3D98Q33713108-B4A9A972-8109-4A6A-9392-526EDE6B66ECQ33731226-93840143-45F6-49AA-BE58-D146998F4101Q33731243-F36F9FAB-A77A-491F-B32A-8E0D56AB59E8Q33747865-D3A20F79-C226-43FC-82C4-10DB032D1C4DQ33870720-B78C7EA6-0D03-47DB-8D63-C8183CFBFB45Q33894621-51AB5C7F-394E-4703-B522-E2D8DF45D52FQ34055904-E4EFFEF6-AB4A-4BD3-8574-9F0898592DC8Q34063628-4FFCCBFF-AB2C-4EDC-8692-7DE6CEF300B7Q34158558-59209C58-AAF1-47E9-9D9D-154190590DECQ34166253-282E045D-E66E-49C7-9451-836C08F6D2A6Q34172458-B92D77AC-F39C-4613-B88E-D91FF6E9AD8FQ34349444-F4FD200A-D407-406F-8FB9-25C438D760DDQ34776944-D40DBAC2-CA15-4E74-B546-157AB3A821F2Q34795088-041E7AF6-A4F4-4DB4-A1AD-10355CBA9F93Q35048066-198254D5-6816-44B0-9488-1C0D61033D94Q35086714-B1FCC330-38DB-40E6-8165-67A909CA9949Q35153080-086BFD79-59F1-488D-A73B-4AD484AD967CQ35340196-7133A89A-5E87-4F1B-8C1C-8AA12DA22E38Q35591425-A03A5BAF-B2C2-4C1F-9E7B-65F962B153C2Q35664978-CF3A6F9D-E65E-49FC-8165-C3DA151FB1C5Q35848706-59D723D0-4C91-4E6B-A4F8-BEC7A901C2B4Q35853990-3B4C3559-A61D-4C70-98FE-DD14D4E31881Q35894676-2AE3E81B-3951-497A-9F10-DBF388BF01C7Q36147497-8CFFFF81-938E-4CA6-8047-335B26054BDDQ36370376-C42F22D2-0D49-4805-9CFA-75D18DB86FCEQ36469695-065187BB-06A4-4006-965B-38EA430D1EDF
P2860
Expanded repertoire of AAV vector serotypes mediate unique patterns of transduction in mouse brain.
description
2008 nî lūn-bûn
@nan
2008 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Expanded repertoire of AAV vec ...... f transduction in mouse brain.
@ast
Expanded repertoire of AAV vec ...... f transduction in mouse brain.
@en
Expanded repertoire of AAV vec ...... f transduction in mouse brain.
@nl
type
label
Expanded repertoire of AAV vec ...... f transduction in mouse brain.
@ast
Expanded repertoire of AAV vec ...... f transduction in mouse brain.
@en
Expanded repertoire of AAV vec ...... f transduction in mouse brain.
@nl
prefLabel
Expanded repertoire of AAV vec ...... f transduction in mouse brain.
@ast
Expanded repertoire of AAV vec ...... f transduction in mouse brain.
@en
Expanded repertoire of AAV vec ...... f transduction in mouse brain.
@nl
P2093
P2860
P356
P1433
P1476
Expanded repertoire of AAV vec ...... of transduction in mouse brain
@en
P2093
Cassia N Cearley
Erin R Carnish
John H Wolfe
Luk H Vandenberghe
Michael K Parente
P2860
P304
P356
10.1038/MT.2008.166
P577
2008-08-19T00:00:00Z