Expanded repertoire of AAV vector serotypes mediate unique patterns of transduction in mouse brain. - Wikidata - awgldk - TriplyDB

Expanded repertoire of AAV vector serotypes mediate unique patterns of transduction in mouse brain.

Expanded repertoire of AAV vector serotypes mediate unique patterns of transduction in mouse brain.

http://www.wikidata.org/entity/Q34664932

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Biology of adeno-associated viral vectors in the central nervous system The prospect of molecular therapy for Angelman syndrome and other monogenic neurologic disorders 3D Imaging of Axons in Transparent Spinal Cords from Rodents and Nonhuman Primates(,.)Gene therapy for metachromatic leukodystrophy.Targeted delivery of self-complementary adeno-associated virus serotype 9 to the brain, using magnetic resonance imaging-guided focused ultrasound Sialic acid deposition impairs the utility of AAV9, but not peptide-modified AAVs for brain gene therapy in a mouse model of lysosomal storage disease Viral transduction of the neonatal brain delivers controllable genetic mosaicism for visualising and manipulating neuronal circuits in vivo.Long-distance axonal transport of AAV9 is driven by dynein and kinesin-2 and is trafficked in a highly motile Rab7-positive compartment.Treatment of congenital neurotransmitter deficiencies by intracerebral ventricular injection of an adeno-associated virus serotype 9 vector.Adenosine kinase, glutamine synthetase and EAAT2 as gene therapy targets for temporal lobe epilepsy.Redirecting N-acetylaspartate metabolism in the central nervous system normalizes myelination and rescues Canavan disease.Directed evolution of adeno-associated virus for glioma cell transduction Retrograde gene delivery to hypoglossal motoneurons using adeno-associated virus serotype 9.Therapeutic benefit of lentiviral-mediated neonatal intracerebral gene therapy in a mouse model of globoid cell leukodystrophy Efficient gene delivery and selective transduction of glial cells in the mammalian brain by AAV serotypes isolated from nonhuman primates.Comparative transduction efficiency of AAV vector serotypes 1-6 in the substantia nigra and striatum of the primate brain.Differential transduction following basal ganglia administration of distinct pseudotyped AAV capsid serotypes in nonhuman primates Two-photon imaging of calcium in virally transfected striate cortical neurons of behaving monkey Global CNS transduction of adult mice by intravenously delivered rAAVrh.8 and rAAVrh.10 and nonhuman primates by rAAVrh.10 Viral vectors for neurotrophic factor delivery: a gene therapy approach for neurodegenerative diseases of the CNS Gene transfer to the CNS using recombinant adeno-associated virus Adeno-associated virus serotypes 1, 8, and 9 share conserved mechanisms for anterograde and retrograde axonal transport.Controlling brain tumor growth by intraventricular administration of an AAV vector encoding IFN-beta.RH10 provides superior transgene expression in mice when compared with natural AAV serotypes for neonatal gene therapy.Specific disruption of astrocytic Ca2+ signaling pathway in vivo by adeno-associated viral transduction.Intracerebroventricular viral injection of the neonatal mouse brain for persistent and widespread neuronal transduction.Phosphorylation dynamics regulate Hsp27-mediated rescue of neuronal plasticity deficits in tau transgenic mice.Capsid serotype and timing of injection determines AAV transduction in the neonatal mice brain.Brain BLAQ: Post-hoc thick-section histochemistry for localizing optogenetic constructs in neurons and their distal terminals Preclinical differences of intravascular AAV9 delivery to neurons and glia: a comparative study of adult mice and nonhuman primates Improving single injection CSF delivery of AAV9-mediated gene therapy for SMA: a dose-response study in mice and nonhuman primates.Gene therapy for the nervous system: challenges and new strategies.Widespread and efficient transduction of spinal cord and brain following neonatal AAV injection and potential disease modifying effect in ALS mice.Bilateral single-site intracerebral injection of a nonpathogenic herpes simplex virus-1 vector decreases anxiogenic behavior in MPS VII mice.Making the White Matter Matters: Progress in Understanding Canavan's Disease and Therapeutic Interventions Through Eight Decades.Controlling AAV Tropism in the Nervous System with Natural and Engineered Capsids.A review of gene therapy in canine and feline models of lysosomal storage disorders.Correction of brain oligodendrocytes by AAVrh.10 intracerebral gene therapy in metachromatic leukodystrophy mice.Use of Adeno-Associated and Herpes Simplex Viral Vectors for In Vivo Neuronal Expression in Mice.A gustotopic map of taste qualities in the mammalian brain

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P2860

Expanded repertoire of AAV vector serotypes mediate unique patterns of transduction in mouse brain.

http://www.wikidata.org/entity/Q34664932

description

2008 nî lūn-bûn

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2008 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

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2008 թվականի օգոստոսին հրատարակված գիտական հոդված

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Expanded repertoire of AAV vec ...... f transduction in mouse brain.

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Expanded repertoire of AAV vec ...... f transduction in mouse brain.

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Expanded repertoire of AAV vec ...... f transduction in mouse brain.

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Expanded repertoire of AAV vec ...... f transduction in mouse brain.

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Expanded repertoire of AAV vec ...... f transduction in mouse brain.

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Expanded repertoire of AAV vec ...... f transduction in mouse brain.

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Expanded repertoire of AAV vec ...... f transduction in mouse brain.

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Molecular Therapy

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Expanded repertoire of AAV vec ...... of transduction in mouse brain

@en

P2093

Cassia N Cearley

http://www.w3.org/2001/XMLSchema#string

Erin R Carnish

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John H Wolfe

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Luk H Vandenberghe

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Michael K Parente

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P2860

Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapy

An autoradiographic study of the organization of the efferent connections of the hippocampal formation in the rat

Inflammation in white matter: clinical and pathophysiological aspects.

Immune responses to adenovirus and adeno-associated virus in humans.

Biology of oligodendrocyte and myelin in the mammalian central nervous system.

Circulating anti-wild-type adeno-associated virus type 2 (AAV2) antibodies inhibit recombinant AAV2 (rAAV2)-mediated, but not rAAV5-mediated, gene transfer in the brain.

Clades of Adeno-associated viruses are widely disseminated in human tissues.

Commissural and intrinsic connections of the rat hippocampus.

The role of macrophage/microglia and astrocytes in the pathogenesis of three neurologic disorders: HIV-associated dementia, Alzheimer disease, and multiple sclerosis.

Immunological aspects of recombinant adeno-associated virus delivery to the mammalian brain

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1710-1718

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10.1038/MT.2008.166

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10

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16

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23181547

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18714307

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3056207

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