AMPK is abnormally activated in tangle- and pre-tangle-bearing neurons in Alzheimer's disease and other tauopathies.
about
Phosphorylation of microtubule-associated protein tau by AMPK-related kinasesClathrin adaptor CALM/PICALM is associated with neurofibrillary tangles and is cleaved in Alzheimer's brainsMolecular Targets in Alzheimer's Disease: From Pathogenesis to TherapeuticsA dual role for AMP-activated protein kinase (AMPK) during neonatal hypoxic-ischaemic brain injury in miceCritical residues involved in tau binding to fyn: implications for tau phosphorylation in Alzheimer's disease.Tau phosphorylation regulates the interaction between BIN1's SH3 domain and Tau's proline-rich domainMammalian target of rapamycin (mTor) mediates tau protein dyshomeostasis: implication for Alzheimer diseaseNeuroglobin Overexpression Inhibits AMPK Signaling and Promotes Cell Anabolism.Association between risk factors for vascular dementia and adiponectin.Docking Studies and Biological Evaluation of a Potential β-Secretase Inhibitor of 3-Hydroxyhericenone F from Hericium erinaceus.Activation of AMPK and inactivation of Akt result in suppression of mTOR-mediated S6K1 and 4E-BP1 pathways leading to neuronal cell death in in vitro models of Parkinson's diseaseNutritional and Pharmacological Strategies to Regulate Microglial Polarization in Cognitive Aging and Alzheimer's Disease.Inhibition of AMP-activated protein kinase signaling alleviates impairments in hippocampal synaptic plasticity induced by amyloid β.LKB1 destabilizes microtubules in myoblasts and contributes to myoblast differentiationRoles of resveratrol and other grape-derived polyphenols in Alzheimer's disease prevention and treatment.CALHM1 deficiency impairs cerebral neuron activity and memory flexibility in mice.Adiponectin is protective against oxidative stress induced cytotoxicity in amyloid-beta neurotoxicityAMPK at the nexus of energetics and aging.Suppression of the HSF1-mediated proteotoxic stress response by the metabolic stress sensor AMPKA systems biology investigation of neurodegenerative dementia reveals a pivotal role of autophagy.Small molecule adenosine 5'-monophosphate activated protein kinase (AMPK) modulators and human diseasesAge-related changes in AMP-activated protein kinase after strokeInsulin Resistance Prevents AMPK-induced Tau Dephosphorylation through Akt-mediated Increase in AMPKSer-485 PhosphorylationAMP-Activated Protein Kinase (AMPK) and Energy-Sensing in the BrainSporadic Alzheimer disease fibroblasts display an oxidative stress phenotypeSensitive quantitative assays for tau and phospho-tau in transgenic mouse modelsAdenosine monophosphate-activated protein kinase overactivation leads to accumulation of α-synuclein oligomers and decrease of neurites.Mitochondrial biogenesis: a therapeutic target for neurodevelopmental disorders and neurodegenerative diseasesProstate-derived sterile 20-like kinases (PSKs/TAOKs) phosphorylate tau protein and are activated in tangle-bearing neurons in Alzheimer disease.Alternative mitochondrial electron transfer for the treatment of neurodegenerative diseases and cancers: Methylene blue connects the dots.AMP-activated protein kinase modulates tau phosphorylation and tau pathology in vivo.The CAMKK2-AMPK kinase pathway mediates the synaptotoxic effects of Aβ oligomers through Tau phosphorylationLatrepirdine is a potent activator of AMP-activated protein kinase and reduces neuronal excitability.Adiponectin as a new paradigm for approaching Alzheimer's disease.A modification-specific peptide-based immunization approach using CRM197 carrier protein: Development of a selective vaccine against pyroglutamate Aβ peptides.Tau protein modifications and interactions: their role in function and dysfunction.AMP-activated protein kinase: a potential player in Alzheimer's disease.Role and Therapeutic Potential of the Pro-Longevity Factor FOXO and Its Regulators in Neurodegenerative Disease.Roles of AMP-activated protein kinase in Alzheimer's disease.Energy dysfunction in Huntington's disease: insights from PGC-1α, AMPK, and CKB.
P2860
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P2860
AMPK is abnormally activated in tangle- and pre-tangle-bearing neurons in Alzheimer's disease and other tauopathies.
description
2010 nî lūn-bûn
@nan
2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
AMPK is abnormally activated i ...... disease and other tauopathies.
@ast
AMPK is abnormally activated i ...... disease and other tauopathies.
@en
AMPK is abnormally activated i ...... disease and other tauopathies.
@nl
type
label
AMPK is abnormally activated i ...... disease and other tauopathies.
@ast
AMPK is abnormally activated i ...... disease and other tauopathies.
@en
AMPK is abnormally activated i ...... disease and other tauopathies.
@nl
prefLabel
AMPK is abnormally activated i ...... disease and other tauopathies.
@ast
AMPK is abnormally activated i ...... disease and other tauopathies.
@en
AMPK is abnormally activated i ...... disease and other tauopathies.
@nl
P2860
P50
P1476
AMPK is abnormally activated i ...... disease and other tauopathies.
@en
P2860
P2888
P304
P356
10.1007/S00401-010-0759-X
P577
2010-10-19T00:00:00Z