The unfolded protein response regulator GRP78/BiP as a novel target for increasing chemosensitivity in malignant gliomas.
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The endoplasmic reticulum stress response in aging and age-related diseasesEssential role of the unfolded protein response regulator GRP78/BiP in protection from neuronal apoptosisThe antitumor natural compound falcarindiol promotes cancer cell death by inducing endoplasmic reticulum stressAdaptive preconditioning in neurological diseases – therapeutic insights from proteostatic perturbationsProtein Folding and Mechanisms of ProteostasisNatural compounds as anticancer agents: Experimental evidenceBacteriophage-derived vectors for targeted cancer gene therapyA new strategy of promoting cisplatin chemotherapeutic efficiency by targeting endoplasmic reticulum stressThe stress-regulated transcription factor CHOP promotes hepatic inflammatory gene expression, fibrosis, and oncogenesisFasting enhances the response of glioma to chemo- and radiotherapyThe short-chain fatty acid receptor GPR43 is transcriptionally regulated by XBP1 in human monocytesInhibition of prolyl 4-hydroxylase, beta polypeptide (P4HB) attenuates temozolomide resistance in malignant glioma via the endoplasmic reticulum stress response (ERSR) pathwaysRegulation of PERK signaling and leukemic cell survival by a novel cytosolic isoform of the UPR regulator GRP78/BiPCancer cells resistant to therapy promote cell surface relocalization of GRP78 which complexes with PI3K and enhances PI(3,4,5)P3 productionGlucose-regulated protein 78 (Grp78) confers chemoresistance to tumor endothelial cells under acidic stressA High-Throughput Screen Identifies 2,9-Diazaspiro[5.5]Undecanes as Inducers of the Endoplasmic Reticulum Stress Response with Cytotoxic Activity in 3D Glioma Cell ModelsKnockdown of ERp57 increases BiP/GRP78 induction and protects against hyperoxia and tunicamycin-induced apoptosis.Endoplasmic Reticulum Stress, Unfolded Protein Response, and Cancer Cell FateCigarette smoke induces endoplasmic reticulum stress and the unfolded protein response in normal and malignant human lung cellsProteomic identification of putative biomarkers of radiotherapy resistance: a possible role for the 26S proteasome?Activation of the unfolded protein response contributes toward the antitumor activity of vorinostat.Cellular stress responses: cell survival and cell deathHKH40A downregulates GRP78/BiP expression in cancer cells.Inhibition of stearoyl-CoA desaturase 1 expression induces CHOP-dependent cell death in human cancer cells.Increase in gene-transcript levels as indicators of up-regulation of the unfolded protein response in spontaneous canine tumors.Stressed to death: targeting endoplasmic reticulum stress response induced apoptosis in gliomas.Cell surface relocalization of the endoplasmic reticulum chaperone and unfolded protein response regulator GRP78/BiP.Targeted nanoparticles that deliver a sustained, specific release of Paclitaxel to irradiated tumors.(-)-Epigallocatechin gallate sensitizes breast cancer cells to paclitaxel in a murine model of breast carcinoma.The deadly connection between endoplasmic reticulum, Ca2+, protein synthesis, and the endoplasmic reticulum stress response in malignant glioma cells.Transcriptional induction of GRP78/BiP by histone deacetylase inhibitors and resistance to histone deacetylase inhibitor-induced apoptosis.Pro-apoptotic and anti-inflammatory properties of the green tea constituent epigallocatechin gallate increase photodynamic therapy responsiveness.Embryonic stem cell (ESC)-mediated transgene delivery induces growth suppression, apoptosis and radiosensitization, and overcomes temozolomide resistance in malignant gliomas.Monoclonal antibody against cell surface GRP78 as a novel agent in suppressing PI3K/AKT signaling, tumor growth, and metastasis.miR-221/222 suppression protects against endoplasmic reticulum stress-induced apoptosis via p27(Kip1)- and MEK/ERK-mediated cell cycle regulation.Changes in oligosaccharide chains of autoantibodies to GRP78 expressed during progression of malignant melanoma stimulate melanoma cell growth and survivalIs there a common upstream link for autophagic and apoptotic cell death in human high-grade gliomas?Cellular stress/the unfolded protein response: relevance to sleep and sleep disorders.GRP78 as potential predictor for breast cancer response to adjuvant taxane therapy.Utilization of the cellular stress response to sensitize cancer cells to TRAIL-mediated apoptosis.
P2860
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P2860
The unfolded protein response regulator GRP78/BiP as a novel target for increasing chemosensitivity in malignant gliomas.
description
2007 nî lūn-bûn
@nan
2007 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
The unfolded protein response ...... sitivity in malignant gliomas.
@ast
The unfolded protein response ...... sitivity in malignant gliomas.
@en
The unfolded protein response ...... sitivity in malignant gliomas.
@nl
type
label
The unfolded protein response ...... sitivity in malignant gliomas.
@ast
The unfolded protein response ...... sitivity in malignant gliomas.
@en
The unfolded protein response ...... sitivity in malignant gliomas.
@nl
prefLabel
The unfolded protein response ...... sitivity in malignant gliomas.
@ast
The unfolded protein response ...... sitivity in malignant gliomas.
@en
The unfolded protein response ...... sitivity in malignant gliomas.
@nl
P2093
P1433
P1476
The unfolded protein response ...... nsitivity in malignant gliomas
@en
P2093
Axel H Schönthal
Florence M Hofman
Peter Pyrko
Thomas C Chen
P304
P356
10.1158/0008-5472.CAN-07-0625
P407
P50
P577
2007-10-01T00:00:00Z