Structure and function of cytochromes P450 2B: from mechanism-based inactivators to X-ray crystal structures and back
about
Structural diversity of eukaryotic membrane cytochrome p450sX-ray crystal structure of the cytochrome P450 2B4 active site mutant F297A in complex with clopidogrel: Insights into compensatory rearrangements of the binding pocketCrystal Structure of Human Cytochrome P450 2D6 with Prinomastat BoundA model of the membrane-bound cytochrome b5-cytochrome P450 complex from NMR and mutagenesis data.Conformational dynamics of CYP3A4 demonstrate the important role of Arg212 coupled with the opening of ingress, egress and solvent channels to dehydrogenation of 4-hydroxy-tamoxifen.Structural and biophysical characterization of human cytochromes P450 2B6 and 2A6 bound to volatile hydrocarbons: analysis and comparison.Inhibition of cytochrome P450 2B4 by environmentally persistent free radical-containing particulate matter.Structure-Function Analysis of Mammalian CYP2B Enzymes Using 7-Substituted Coumarin Derivatives as Probes: Utility of Crystal Structures and Molecular Modeling in Understanding Xenobiotic MetabolismCoumarin Derivatives as Substrate Probes of Mammalian Cytochromes P450 2B4 and 2B6: Assessing the Importance of 7-Alkoxy Chain Length, Halogen Substitution, and Non-Active Site Mutations.Correlating structure and function of drug-metabolizing enzymes: progress and ongoing challenges.Functional characterization of cytochromes P450 2B from the desert woodrat Neotoma lepida.Hepatic cytochromes P450: structural degrons and barcodes, posttranslational modifications and cellular adapters in the ERAD-endgame.Analysis of Cytochrome P450 Conserved Sequence Motifs between Helices E and H: Prediction of Critical Motifs and Residues in Enzyme Functions.Roles of Residues F206 and V367 in Human CYP2B6: Effects of Mutations on Androgen Hydroxylation, Mechanism-Based Inactivation, and Reversible Inhibition.Insights into the role of substrates on the interaction between cytochrome b5 and cytochrome P450 2B4 by NMR.Halogen-π Interactions in the Cytochrome P450 Active Site: Structural Insights into Human CYP2B6 Substrate Selectivity.
P2860
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P2860
Structure and function of cytochromes P450 2B: from mechanism-based inactivators to X-ray crystal structures and back
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Structure and function of cyto ...... ay crystal structures and back
@en
Structure and function of cyto ...... ay crystal structures and back
@nl
type
label
Structure and function of cyto ...... ay crystal structures and back
@en
Structure and function of cyto ...... ay crystal structures and back
@nl
prefLabel
Structure and function of cyto ...... ay crystal structures and back
@en
Structure and function of cyto ...... ay crystal structures and back
@nl
P2860
P356
P1476
Structure and function of cyto ...... ay crystal structures and back
@en
P2093
James R Halpert
P2860
P304
P356
10.1124/DMD.111.039719
P577
2011-04-18T00:00:00Z