Modulation of mitochondrial function and morphology by interaction of Omi/HtrA2 with the mitochondrial fusion factor OPA1.
about
Idebenone and resveratrol extend lifespan and improve motor function of HtrA2 knockout miceMitochondrial DNA and primary mitochondrial dysfunction in Parkinson's disease.Mitochondrial dysfunction-associated OPA1 cleavage contributes to muscle degeneration: preventative effect of hydroxytyrosol acetate.Neural-specific deletion of Htra2 causes cerebellar neurodegeneration and defective processing of mitochondrial OPA1.Phosphorylation of HtrA2 by cyclin-dependent kinase-5 is important for mitochondrial function.Altered enzymatic activity and allele frequency of OMI/HTRA2 in Alzheimer's diseaseMitochondrial dynamics and Parkinson's disease: focus on parkin.Dissecting the role of the mitochondrial chaperone mortalin in Parkinson's disease: functional impact of disease-related variants on mitochondrial homeostasis.Protease Omi facilitates neurite outgrowth in mouse neuroblastoma N2a cells by cleaving transcription factor E2F1The use of primary human fibroblasts for monitoring mitochondrial phenotypes in the field of Parkinson's disease.Loss of HtrA2/Omi activity in non-neuronal tissues of adult mice causes premature aging.Cardiac Specific Overexpression of Mitochondrial Omi/HtrA2 Induces Myocardial Apoptosis and Cardiac Dysfunction.Pathogenic variants in HTRA2 cause an early-onset mitochondrial syndrome associated with 3-methylglutaconic aciduria.Genetic insights into sporadic Parkinson's disease pathogenesis.Mitochondrial proteolytic stress induced by loss of mortalin function is rescued by Parkin and PINK1.Mitochondrial involvement in cell death of non-mammalian eukaryotes.Mitochondrial dynamics: the intersection of form and function.Mitochondrial quality control pathways as determinants of metabolic health.Stress Conditions Increase Vimentin Cleavage by Omi/HtrA2 Protease in Human Primary Neurons and Differentiated Neuroblastoma Cells.HtrA2 deficiency causes mitochondrial uncoupling through the F₁F₀-ATP synthase and consequent ATP depletion.Metformin reverses TRAP1 mutation-associated alterations in mitochondrial function in Parkinson's disease.Parkinson Disease from Mendelian Forms to Genetic Susceptibility: New Molecular Insights into the Neurodegeneration Process.
P2860
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P2860
Modulation of mitochondrial function and morphology by interaction of Omi/HtrA2 with the mitochondrial fusion factor OPA1.
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Modulation of mitochondrial fu ...... ochondrial fusion factor OPA1.
@ast
Modulation of mitochondrial fu ...... ochondrial fusion factor OPA1.
@en
Modulation of mitochondrial fu ...... ochondrial fusion factor OPA1.
@nl
type
label
Modulation of mitochondrial fu ...... ochondrial fusion factor OPA1.
@ast
Modulation of mitochondrial fu ...... ochondrial fusion factor OPA1.
@en
Modulation of mitochondrial fu ...... ochondrial fusion factor OPA1.
@nl
prefLabel
Modulation of mitochondrial fu ...... ochondrial fusion factor OPA1.
@ast
Modulation of mitochondrial fu ...... ochondrial fusion factor OPA1.
@en
Modulation of mitochondrial fu ...... ochondrial fusion factor OPA1.
@nl
P2093
P2860
P50
P1476
Modulation of mitochondrial fu ...... ochondrial fusion factor OPA1.
@en
P2093
Dalila Ciceri
Elena Ziviani
Hartwig Wolburg
L Miguel Martins
Nicole Kieper
Philipp J Kahle
P2860
P304
P356
10.1016/J.YEXCR.2010.01.005
P407
P577
2010-01-11T00:00:00Z