Β-arrestin: a signaling molecule and potential therapeutic target for heart failure. - Wikidata - awgldk - TriplyDB

Β-arrestin: a signaling molecule and potential therapeutic target for heart failure.

Β-arrestin: a signaling molecule and potential therapeutic target for heart failure.

http://www.wikidata.org/entity/Q34716806

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Cardiovascular Dysfunction Following Burn Injury: What We Have Learned from Rat and Mouse Models Regulators of G-protein signaling in the heart and their potential as therapeutic targets.Ligand-specific endocytic dwell times control functional selectivity of the cannabinoid receptor 1 β-arrestin2/miR-155/GSK3β regulates transition of 5'-azacytizine-induced Sca-1-positive cells to cardiomyocytes Chemerin Elicits Potent Constrictor Actions via Chemokine-Like Receptor 1 (CMKLR1), not G-Protein-Coupled Receptor 1 (GPR1), in Human and Rat Vasculature.β-Arrestins regulate human cardiac fibroblast transformation and collagen synthesis in adverse ventricular remodeling β-arrestin2 in infiltrated macrophages inhibits excessive inflammation after myocardial infarction Heterotrimeric G protein-mediated signaling and its non-canonical regulation in the heart.Simultaneous parasympathetic and sympathetic activation reveals altered autonomic control of heart rate, vascular tension, and epinephrine release in anesthetized hypertensive rats Regulation of cellular oxidative stress and apoptosis by G protein-coupled receptor kinase-2; The role of NADPH oxidase 4 The β-arrestin-biased ligand TRV120023 inhibits angiotensin II-induced cardiac hypertrophy while preserving enhanced myofilament response to calcium Current and future G protein-coupled receptor signaling targets for heart failure therapy βArrestins in cardiac G protein-coupled receptor signaling and function: partners in crime or "good cop, bad cop"?Negative impact of β-arrestin-1 on post-myocardial infarction heart failure via cardiac and adrenal-dependent neurohormonal mechanisms.Arrestin-biased AT1R agonism induces acute catecholamine secretion through TRPC3 coupling.Taking the heart failure battle inside the cell: small molecule targeting of Gβγ subunits An expanded family of arrestins regulate metabolism.Key role of ERK1/2 molecular scaffolds in heart pathology.Molecular targeting of Gα and Gβγ subunits: a potential approach for cancer therapeutics.β-Arrestins in the immune system Employing novel animal models in the design of clinically efficacious GPCR ligands.β1-adrenergic receptor and sphingosine-1-phosphate receptor 1 (S1PR1) reciprocal downregulation influences cardiac hypertrophic response and progression to heart failure: protective role of S1PR1 cardiac gene therapy G protein-coupled receptor kinase 2 promotes cardiac hypertrophy Cardioprotective Action of Ginkgo biloba Extract against Sustained β-Adrenergic Stimulation Occurs via Activation of M2/NO Pathway.Calcific Aortic Valve Disease: Part 2-Morphomechanical Abnormalities, Gene Reexpression, and Gender Effects on Ventricular Hypertrophy and Its Reversibility.Diverse regulation of cardiac expression of relaxin receptor by α1- and β1-adrenoceptors.Conducting the G-protein Coupled Receptor (GPCR) Signaling Symphony in Cardiovascular Diseases: New Therapeutic Approaches Ang-(1-7) is an endogenous β-arrestin-biased agonist of the AT1 receptor with protective action in cardiac hypertrophy.Novel strategies for the treatment of heart failure Measurement of Receptor Signaling Bias.Different expression of adrenoceptors and GRKs in the human myocardium depends on heart failure etiology and correlates to clinical variables.You're Not under Arrest: Worry-free with β-arrestin.

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Β-arrestin: a signaling molecule and potential therapeutic target for heart failure.

http://www.wikidata.org/entity/Q34716806

description

2010 nî lūn-bûn

@nan

2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

@zh-hk

2010年論文

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2010年論文

@zh-tw

2010年论文

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name

Β-arrestin: a signaling molecule and potential therapeutic target for heart failure.

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Β-arrestin: a signaling molecule and potential therapeutic target for heart failure.

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Β-arrestin: a signaling molecule and potential therapeutic target for heart failure.

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type

label

Β-arrestin: a signaling molecule and potential therapeutic target for heart failure.

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Β-arrestin: a signaling molecule and potential therapeutic target for heart failure.

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Β-arrestin: a signaling molecule and potential therapeutic target for heart failure.

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prefLabel

Β-arrestin: a signaling molecule and potential therapeutic target for heart failure.

@ast

Β-arrestin: a signaling molecule and potential therapeutic target for heart failure.

@en

Β-arrestin: a signaling molecule and potential therapeutic target for heart failure.

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J.YJMCC.2010.11.005

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Journal of Molecular and Cellular Cardiology

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Β-arrestin: a signaling molecule and potential therapeutic target for heart failure.

@en

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Chetan B Patel

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Howard A Rockman

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Nabila Noor

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P2860

Beta-arrestin-dependent formation of beta2 adrenergic receptor-Src protein kinase complexes

Functional Selectivity and Classical Concepts of Quantitative Pharmacology

beta-Arrestin: a protein that regulates beta-adrenergic receptor function

Functional specialization of beta-arrestin interactions revealed by proteomic analysis

Mitogen-activated protein kinases activate the serine/threonine kinases Mnk1 and Mnk2

Phosphodiesterase activation by photoexcited rhodopsin is quenched when rhodopsin is phosphorylated and binds the intrinsic 48-kDa protein of rod outer segments

Transduction of receptor signals by beta-arrestins

Regulation of receptor trafficking by GRKs and arrestins

Independent beta-arrestin2 and Gq/protein kinase Czeta pathways for ERK stimulated by angiotensin type 1A receptors in vascular smooth muscle cells converge on transactivation of the epidermal growth factor receptor

{beta}-Arrestin-2 Mediates Anti-apoptotic Signaling through Regulation of BAD Phosphorylation

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