Characterization of ceramide synthase 2: tissue distribution, substrate specificity, and inhibition by sphingosine 1-phosphate.
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Mutations in CERS3 cause autosomal recessive congenital ichthyosis in humans2-Hydroxy-ceramide synthesis by ceramide synthase family: enzymatic basis for the preference of FA chain lengthStress-induced ER to Golgi translocation of ceramide synthase 1 is dependent on proteasomal processingAblation of neuronal ceramide synthase 1 in mice decreases ganglioside levels and expression of myelin-associated glycoprotein in oligodendrocytesCeramide synthases at the centre of sphingolipid metabolism and biologyAn overview of sphingolipid metabolism: from synthesis to breakdownMammalian ceramide synthasesA critical role for ceramide synthase 2 in liver homeostasis: II. insights into molecular changes leading to hepatopathyFTY720 inhibits ceramide synthases and up-regulates dihydrosphingosine 1-phosphate formation in human lung endothelial cellsRoles of bioactive sphingolipids in cancer biology and therapeuticsThe role of sphingosine-1-phosphate in endothelial barrier functionAlkaline Ceramidase 3 Deficiency Results in Purkinje Cell Degeneration and Cerebellar Ataxia Due to Dyshomeostasis of Sphingolipids in the BrainA deficiency of ceramide biosynthesis causes cerebellar purkinje cell neurodegeneration and lipofuscin accumulationCeramide as a Target of Marine Triterpene Glycosides for Treatment of Human Myeloid LeukemiaAlterations of the Ceramide Metabolism in the Peri-Infarct Cortex Are Independent of the Sphingomyelinase Pathway and Not Influenced by the Acid Sphingomyelinase Inhibitor FluoxetineAlkyne lipids as substrates for click chemistry-based in vitro enzymatic assaysEctopic expression of ceramide synthase 2 in neurons suppresses neurodegeneration induced by ceramide synthase 1 deficiencyThe apoptotic mechanism of action of the sphingosine kinase 1 selective inhibitor SKI-178 in human acute myeloid leukemia cell lines.Drugging sphingosine kinases.A metabolic shift favoring sphingosine 1-phosphate at the expense of ceramide controls glioblastoma angiogenesis.Ceramide-mediated insulin resistance and impairment of cognitive-motor functionsNitrosamine exposure causes insulin resistance diseases: relevance to type 2 diabetes mellitus, non-alcoholic steatohepatitis, and Alzheimer's diseaseNitrosamine exposure exacerbates high fat diet-mediated type 2 diabetes mellitus, non-alcoholic steatohepatitis, and neurodegeneration with cognitive impairment.Membrane domain formation, interdigitation, and morphological alterations induced by the very long chain asymmetric C24:1 ceramide.The Concise Guide to PHARMACOLOGY 2013/14: enzymes.Adult ceramide synthase 2 (CERS2)-deficient mice exhibit myelin sheath defects, cerebellar degeneration, and hepatocarcinomas.A novel tumor metastasis suppressor gene LASS2/TMSG1 interacts with vacuolar ATPase through its homeodomain.Neurons and oligodendrocytes recycle sphingosine 1-phosphate to ceramide: significance for apoptosis and multiple sclerosisEarly limited nitrosamine exposures exacerbate high fat diet-mediated type 2 diabetes and neurodegeneration.Antiapoptotic roles of ceramide-synthase-6-generated C16-ceramide via selective regulation of the ATF6/CHOP arm of ER-stress-response pathways.Transcript profiling and lipidomic analysis of ceramide subspecies in mouse embryonic stem cells and embryoid bodies.An introduction to sphingolipid metabolism and analysis by new technologiesSphingosine 1-phosphate lyase deficiency disrupts lipid homeostasis in liverA critical role for ceramide synthase 2 in liver homeostasis: I. alterations in lipid metabolic pathways.Sphingolipids in obesity, type 2 diabetes, and metabolic disease.Efficacy of nutritional interventions to lower circulating ceramides in young adults: FRUVEDomic pilot studyHigh fat diet induced hepatic steatosis and insulin resistance: Role of dysregulated ceramide metabolism.Brain lipidomes of subcortical ischemic vascular dementia and mixed dementiaHepatic ceramide may mediate brain insulin resistance and neurodegeneration in type 2 diabetes and non-alcoholic steatohepatitisDual functions of the trans-2-enoyl-CoA reductase TER in the sphingosine 1-phosphate metabolic pathway and in fatty acid elongation.
P2860
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P2860
Characterization of ceramide synthase 2: tissue distribution, substrate specificity, and inhibition by sphingosine 1-phosphate.
description
2007 nî lūn-bûn
@nan
2007 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Characterization of ceramide s ...... on by sphingosine 1-phosphate.
@ast
Characterization of ceramide s ...... on by sphingosine 1-phosphate.
@en
Characterization of ceramide s ...... on by sphingosine 1-phosphate.
@nl
type
label
Characterization of ceramide s ...... on by sphingosine 1-phosphate.
@ast
Characterization of ceramide s ...... on by sphingosine 1-phosphate.
@en
Characterization of ceramide s ...... on by sphingosine 1-phosphate.
@nl
prefLabel
Characterization of ceramide s ...... on by sphingosine 1-phosphate.
@ast
Characterization of ceramide s ...... on by sphingosine 1-phosphate.
@en
Characterization of ceramide s ...... on by sphingosine 1-phosphate.
@nl
P2093
P356
P1476
Characterization of ceramide s ...... on by sphingosine 1-phosphate.
@en
P2093
Alfred H Merrill
Elad L Laviad
Hyejung Park
Irene Pankova-Kholmyansky
Sharon Epstein
P304
P356
10.1074/JBC.M707386200
P407
P577
2007-12-28T00:00:00Z