Long-range cooperative binding effects in a T cell receptor variable domain.
about
Staphylococcal superantigens in colonization and diseaseStructural basis of T-cell specificity and activation by the bacterial superantigen TSST-1A Novel Loop Domain in Superantigens Extends their T Cell Receptor Recognition SiteThermodynamically reengineering the listerial invasion complex InlA/E-cadherinMolecular Architecture of the Major Histocompatibility Complex Class I-binding Site of Ly49 Natural Killer Cell ReceptorsAssessing Energetic Contributions to Binding from a Disordered Region in a Protein−Protein Interaction,Specificity and cooperativity at β-lactamase position 104 in TEM-1/BLIP and SHV-1/BLIP interactionsComputational Design of the Affinity and Specificity of a Therapeutic T Cell ReceptorThe modular organization of domain structures: insights into protein-protein bindingOptimized hydrophobic interactions and hydrogen bonding at the target-ligand interface leads the pathways of drug-designingUptake and intracellular trafficking of superantigens in dendritic cells.Spatial chemical conservation of hot spot interactions in protein-protein complexes.Analysis on multi-domain cooperation for predicting protein-protein interactions.Structure-based design of a T-cell receptor leads to nearly 100-fold improvement in binding affinity for pepMHC.DECK: Distance and environment-dependent, coarse-grained, knowledge-based potentials for protein-protein docking.TCR recognition of peptide/MHC class II complexes and superantigensSpecific increase in potency via structure-based design of a TCR.The T cell receptor beta-chain second complementarity determining region loop (CDR2beta governs T cell activation and Vbeta specificity by bacterial superantigensA viral CTL escape mutation leading to immunoglobulin-like transcript 4-mediated functional inhibition of myelomonocytic cellsHuman scFvs That Counteract Bioactivities of Staphylococcus aureus TSST-1.Engineering a soluble high-affinity receptor domain that neutralizes staphylococcal enterotoxin C in rabbit models of diseasePrediction of contact matrix for protein-protein interaction.The Missing Heritability in T1D and Potential New Targets for Prevention.Soluble T cell receptor Vβ domains engineered for high-affinity binding to staphylococcal or streptococcal superantigensStaphylococcus enterotoxin profile of China isolates and the superantigenicity of some novel enterotoxins.Combinations of affinity-enhancing mutations in a T cell receptor reveal highly nonadditive effects within and between complementarity determining regions and chains.HotRegion: a database of predicted hot spot clustersAn interdomain boundary in RAG1 facilitates cooperative binding to RAG2 in formation of the V(D)J recombinase complex.Predicting domain-domain interaction based on domain profiles with feature selection and support vector machines.Subtle changes at the variable domain interface of the T-cell receptor can strongly increase affinity.Emerging Concepts in TCR Specificity: Rationalizing and (Maybe) Predicting Outcomes.Evolution of In Silico Strategies for Protein-Protein Interaction Drug Discovery
P2860
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P2860
Long-range cooperative binding effects in a T cell receptor variable domain.
description
2006 nî lūn-bûn
@nan
2006 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Long-range cooperative binding effects in a T cell receptor variable domain.
@ast
Long-range cooperative binding effects in a T cell receptor variable domain.
@en
Long-range cooperative binding effects in a T cell receptor variable domain.
@nl
type
label
Long-range cooperative binding effects in a T cell receptor variable domain.
@ast
Long-range cooperative binding effects in a T cell receptor variable domain.
@en
Long-range cooperative binding effects in a T cell receptor variable domain.
@nl
prefLabel
Long-range cooperative binding effects in a T cell receptor variable domain.
@ast
Long-range cooperative binding effects in a T cell receptor variable domain.
@en
Long-range cooperative binding effects in a T cell receptor variable domain.
@nl
P2093
P2860
P356
P1476
Long-range cooperative binding effects in a T cell receptor variable domain
@en
P2093
A K M Nur-ur Rahman
Beenu Moza
Christine A Herfst
David M Kranz
Rebecca A Buonpane
P2860
P304
P356
10.1073/PNAS.0600220103
P407
P577
2006-06-20T00:00:00Z