A conformational rearrangement in the spliceosome sets the stage for Prp22-dependent mRNA release.
about
SKIP counteracts p53-mediated apoptosis via selective regulation of p21Cip1 mRNA splicingSF1 and SF2 helicases: family mattersRNA helicases at work: binding and rearrangingDEAD-box proteins as RNA helicases and chaperonesThe organization and contribution of helicases to RNA splicingFunctional roles of DExD/H-box RNA helicases in Pre-mRNA splicingRegulation of DEAH/RHA helicases by G-patch proteinsRNA helicases in splicingSplicing fidelity: DEAD/H-box ATPases as molecular clocksRNA helicase proteins as chaperones and remodelersPrp43p contains a processive helicase structural architecture with a specific regulatory domainCryo-EM structure of the spliceosome immediately after branchingThe DExD/H-box ATPase Prp2p destabilizes and proofreads the catalytic RNA core of the spliceosome.Splicing proofreading at 5' splice sites by ATPase Prp28p.Splicing factor Cwc22 is required for the function of Prp2 and for the spliceosome to escape from a futile pathway.Molecular dissection of step 2 catalysis of yeast pre-mRNA splicing investigated in a purified system.Spliceosome Structure and FunctionConformational dynamics of single pre-mRNA molecules during in vitro splicing.The role of exon sequences in C complex spliceosome structureIncomplete splicing, cell division defects, and hematopoietic blockage in dhx8 mutant zebrafish.Biased Brownian ratcheting leads to pre-mRNA remodeling and capture prior to first-step splicing.Breaking up the C complex spliceosome shows stable association of proteins with the lariat intron intermediateRearrangements within human spliceosomes captured after exon ligation.DEAH-box ATPase Prp16 has dual roles in remodeling of the spliceosome in catalytic steps.Roles of DEAD-box proteins in RNA and RNP Folding.Limited portability of G-patch domains in regulators of the Prp43 RNA helicase required for pre-mRNA splicing and ribosomal RNA maturation in Saccharomyces cerevisiae.Functional complexity and regulation through RNA dynamicsFunctional roles of protein splicing factors.The interaction of Prp2 with a defined region of the intron is required for the first splicing reaction.A weak spliceosome-binding domain of Yju2 functions in the first step and bypasses Prp16 in the second step of splicingSpliceosomal DEAH-Box ATPases Remodel Pre-mRNA to Activate Alternative Splice Sites.Superfamily 2 helicasesAssembly of ribosomes and spliceosomes: complex ribonucleoprotein machinesThe spliceosomal proteome: at the heart of the largest cellular ribonucleoprotein machine.The mechanism of the second step of pre-mRNA splicing.Staying on message: ensuring fidelity in pre-mRNA splicing.Lives that introns lead after splicing.Human cactin interacts with DHX8 and SRRM2 to assure efficient pre-mRNA splicing and sister chromatid cohesion.Splicing of Nascent RNA Coincides with Intron Exit from RNA Polymerase II.Dissection of the factor requirements for spliceosome disassembly and the elucidation of its dissociation products using a purified splicing system.
P2860
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P2860
A conformational rearrangement in the spliceosome sets the stage for Prp22-dependent mRNA release.
description
2008 nî lūn-bûn
@nan
2008 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
name
A conformational rearrangement ...... Prp22-dependent mRNA release.
@ast
A conformational rearrangement ...... Prp22-dependent mRNA release.
@en
A conformational rearrangement ...... Prp22-dependent mRNA release.
@nl
type
label
A conformational rearrangement ...... Prp22-dependent mRNA release.
@ast
A conformational rearrangement ...... Prp22-dependent mRNA release.
@en
A conformational rearrangement ...... Prp22-dependent mRNA release.
@nl
prefLabel
A conformational rearrangement ...... Prp22-dependent mRNA release.
@ast
A conformational rearrangement ...... Prp22-dependent mRNA release.
@en
A conformational rearrangement ...... Prp22-dependent mRNA release.
@nl
P2860
P1433
P1476
A conformational rearrangement ...... Prp22-dependent mRNA release.
@en
P2860
P304
P356
10.1016/J.MOLCEL.2008.05.003
P50
P577
2008-06-01T00:00:00Z