The total synthesis of (-)-cyanthiwigin F by means of double catalytic enantioselective alkylation
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Introducing a Hydrogen-Bond Donor into a Weakly Nucleophilic Brønsted Base: Alkali Metal Hexamethyldisilazides (MHMDS, M=Li, Na, K, Rb and Cs) with AmmoniaThe Construction of All-Carbon Quaternary Stereocenters by Use of Pd-Catalyzed Asymmetric Allylic Alkylation Reactions in Total SynthesisMechanistic origin of the stereodivergence in decarboxylative allylationPREPARATION OF (S)-2-Allyl-2-methylcyclohexanone (Cyclohexanone, 2-methyl-2-(2-propen-1-yl)-, (2S)-).Formal total syntheses of classic natural product target molecules via palladium-catalyzed enantioselective alkylation.Transition metal-catalyzed decarboxylative allylation and benzylation reactionsDeacylative allylation: allylic alkylation via retro-Claisen activation.Synthesis and Exploration of Electronically Modified (R)-5,5-Dimethyl-(p-CF3)3-i-PrPHOX in Palladium-Catalyzed Enantio- and Diastereoselective Allylic Alkylation: A Practical Alternative to (R)-(p-CF3)3-t-BuPHOX.Constructing molecular complexity and diversity: total synthesis of natural products of biological and medicinal importance.Catalytic double stereoinduction in asymmetric allylic alkylation of oxindoles.Catalytic enantioselective synthesis of quaternary carbon stereocentresAn Efficient Protocol for the Palladium-catalyzed Asymmetric Decarboxylative Allylic Alkylation Using Low Palladium Concentrations and a Palladium(II) Precatalyst.Molybdenum-catalyzed asymmetric allylic alkylation of 3-alkyloxindoles: reaction development and applicationsConversion of cyanthiwigin U to related cyanthiwigins: total syntheses of cyanthiwigin W and cyanthiwigin Z.Conformations of N-heterocyclic carbene ligands in ruthenium complexes relevant to olefin metathesis.Synthetic efforts toward cyathane diterpenoid natural productsNatural products as inspiration for the development of asymmetric catalysis.Expanding insight into asymmetric palladium-catalyzed allylic alkylation of N-heterocyclic molecules and cyclic ketonesDevelopment of asymmetric deacylative allylation.Gas extrusion in natural products total synthesis.Advances in Stereoconvergent Catalysis from 2005 to 2015: Transition-Metal-Mediated Stereoablative Reactions, Dynamic Kinetic Resolutions, and Dynamic Kinetic Asymmetric Transformations.Direct Asymmetric Alkylation of Ketones: Still Unconquered.Total syntheses of cyanthiwigins B, F, and G.Evolution of catalytic stereoselective olefin metathesis: from ancillary transformation to purveyor of stereochemical identity.Synthetic studies toward lapidilectine-type Kopsia alkaloids.Enantioselective construction of quaternary N-heterocycles by palladium-catalysed decarboxylative allylic alkylation of lactams.Catalytic enantioselective approach to the eudesmane sesquiterpenoids: total synthesis of (+)-carissone.Effects of NHC-backbone substitution on efficiency in ruthenium-based olefin metathesis.Construction of Tertiary Chiral Centers by Pd-catalyzed Asymmetric Allylic Alkylation of Prochiral Enolate EquivalentsPalladium/N-heterocyclic carbene catalysed regio and diastereoselective reaction of ketones with allyl reagents via inner-sphere mechanism.A unified approach to the daucane and sphenolobane bicyclo[5.3.0]decane core: enantioselective total syntheses of daucene, daucenal, epoxydaucenal B, and 14-para-anisoyloxydauc-4,8-diene.Enantioselective synthesis of the 5-6-7 carbocyclic core of the gagunin diterpenoids.Enantioselective synthesis of a hydroxymethyl-cis-1,3-cyclopentenediol building block.Parallel kinetic resolution approach to the cyathane and cyanthiwigin diterpenes using a cyclopropanation/Cope rearrangement.The catalytic enantioselective total synthesis of (+)-liphagal.Synthesis of enantioenriched γ-quaternary cycloheptenones using a combined allylic alkylation/Stork-Danheiser approach: preparation of mono-, bi-, and tricyclic systems.Enantioselective decarboxylative alkylation reactions: catalyst development, substrate scope, and mechanistic studies.Low catalyst loadings in olefin metathesis: synthesis of nitrogen heterocycles by ring-closing metathesisHighly selective olefin-assisted palladium-catalyzed oxidative carbocyclization via remote olefin insertion.Copper-catalyzed Direct 2-Arylation of Benzoxazoles and Benzoimidazoles with Aryl Bromides and Cytotoxicity of Products.
P2860
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P2860
The total synthesis of (-)-cyanthiwigin F by means of double catalytic enantioselective alkylation
description
2008 nî lūn-bûn
@nan
2008 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
The total synthesis of (-)-cya ...... ic enantioselective alkylation
@ast
The total synthesis of (-)-cya ...... ic enantioselective alkylation
@en
type
label
The total synthesis of (-)-cya ...... ic enantioselective alkylation
@ast
The total synthesis of (-)-cya ...... ic enantioselective alkylation
@en
prefLabel
The total synthesis of (-)-cya ...... ic enantioselective alkylation
@ast
The total synthesis of (-)-cya ...... ic enantioselective alkylation
@en
P2860
P356
P1433
P1476
The total synthesis of (-)-cya ...... ic enantioselective alkylation
@en
P2093
Brian M Stoltz
John A Enquist
P2860
P2888
P304
P356
10.1038/NATURE07046
P407
P577
2008-06-01T00:00:00Z
P5875
P6179
1032004209