Enantioselective construction of quaternary N-heterocycles by palladium-catalysed decarboxylative allylic alkylation of lactams.
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Selective syntheses of leuconolam, leuconoxine, and mersicarpine alkaloids from a common intermediate through regiocontrolled cyclizations by Staudinger reactions†Electronic supplementary information (ESI) available: Experimental details and proceduThe Construction of All-Carbon Quaternary Stereocenters by Use of Pd-Catalyzed Asymmetric Allylic Alkylation Reactions in Total SynthesisA Cooperative N-Heterocyclic Carbene/Palladium Catalysis System.Formal total syntheses of classic natural product target molecules via palladium-catalyzed enantioselective alkylation.Enantioselective synthesis of α-secondary and α-tertiary piperazin-2-ones and piperazines by catalytic asymmetric allylic alkylation.Synthesis and Exploration of Electronically Modified (R)-5,5-Dimethyl-(p-CF3)3-i-PrPHOX in Palladium-Catalyzed Enantio- and Diastereoselective Allylic Alkylation: A Practical Alternative to (R)-(p-CF3)3-t-BuPHOX.An Efficient Protocol for the Palladium-catalyzed Asymmetric Decarboxylative Allylic Alkylation Using Low Palladium Concentrations and a Palladium(II) Precatalyst.Expanding insight into asymmetric palladium-catalyzed allylic alkylation of N-heterocyclic molecules and cyclic ketonesDevelopment of asymmetric deacylative allylation.Raising the pKa limit of "soft" nucleophiles in palladium-catalyzed allylic substitutions: application of diarylmethane pronucleophiles.Palladium-Catalyzed Asymmetric Alkylation in the Synthesis of Cyclopentanoid and Cycloheptanoid Core Structures Bearing All-Carbon Quaternary Stereocenters.Construction of Tertiary Chiral Centers by Pd-catalyzed Asymmetric Allylic Alkylation of Prochiral Enolate EquivalentsEnantio-, diastereo-, and regioselective iridium-catalyzed asymmetric allylic alkylation of acyclic β-ketoesters.Enantioselective Pd-Catalyzed Allylic Alkylation Reactions of Dihydropyrido[1,2-a]indolone Substrates: Efficient Syntheses of (-)-Goniomitine, (+)-Aspidospermidine, and (-)-Quebrachamine.The reaction mechanism of the enantioselective Tsuji allylation: inner-sphere and outer-sphere pathways, internal rearrangements, and asymmetric C-C bond formation.Enantioselective synthesis of α-quaternary Mannich adducts by palladium-catalyzed allylic alkylation: total synthesis of (+)-sibirinine.Enantioselective construction of α-quaternary cyclobutanones by catalytic asymmetric allylic alkylation.Stereoselective β-C-glycosylation by a palladium-catalyzed decarboxylative allylation: formal synthesis of aspergillide A.Enantioselective palladium-catalyzed decarboxylative allylation of carbazolones and indolones: formal synthesis of (+)-kopsihainanine A.Facile access to cis-2,6-disubstituted tetrahydropyrans by palladium-catalyzed decarboxylative allylation: total syntheses of (±)-centrolobine and (+)-decytospolides A and B.Asymmetric Synthesis of All-Carbon Quaternary Spirocycles via a Catalytic Enantioselective Allylic Alkylation Strategy.Sequential Ruthenium Catalysis for Olefin Isomerization and Oxidation: Application to the Synthesis of Unusual Amino Acids.Palladium(II)-catalyzed allylic C-H oxidation of hindered substrates featuring tunable selectivity over extent of oxidation.A FISCHER INDOLIZATION STRATEGY TOWARD THE TOTAL SYNTHESIS OF (-)-GONIOMITINE.Copper(i)-catalyzed radical decarboxylative imidation of carboxylic acids with N-fluoroarylsulfonimides.Enantioselective Construction of Acyclic Quaternary Carbon Stereocenters: Palladium-Catalyzed Decarboxylative Allylic Alkylation of Fully Substituted Amide Enolates.Iridium-Catalyzed Enantioselective Allylic Substitution of Aliphatic Esters with Silyl Ketene Acetals as the Ester Enolates.Synthesis of thieno[2,3-b]quinoline and selenopheno[2,3-b]quinoline derivatives via iodocyclization reaction and a DFT mechanistic study.Nickel-Catalyzed Reductive Allylation of Tertiary Alkyl Halides with Allylic Carbonates.Enantioselective synthesis of sterically hindered α-allyl-α-aryl oxindoles via palladium-catalysed decarboxylative asymmetric allylic alkylation.One-pot synthesis of β-N-glycosyl imidazole analogues via a palladium-catalysed decarboxylative allylation.β-Type glycosidic bond formation by palladium-catalyzed decarboxylative allylation.Enantioselective construction of quaternary tetrahydropyridines by palladium-catalyzed vinylborylation of alkenes.Rhodium-catalyzed chemo- and regioselective decarboxylative addition of β-ketoacids to alkynes.Nickel-catalyzed enantioselective allylic alkylation of lactones and lactams with unactivated allylic alcohols.Highly functionalized piperidines: Free radical scavenging, anticancer activity, DNA interaction and correlation with biological activity
P2860
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P2860
Enantioselective construction of quaternary N-heterocycles by palladium-catalysed decarboxylative allylic alkylation of lactams.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Enantioselective construction ...... allylic alkylation of lactams.
@en
type
label
Enantioselective construction ...... allylic alkylation of lactams.
@en
prefLabel
Enantioselective construction ...... allylic alkylation of lactams.
@en
P2093
P2860
P356
P1433
P1476
Enantioselective construction ...... allylic alkylation of lactams.
@en
P2093
Brian M Stoltz
David E White
Douglas C Behenna
Scott C Virgil
Taiga Yurino
Yiyang Liu
P2860
P2888
P304
P356
10.1038/NCHEM.1222
P577
2011-12-18T00:00:00Z
P5875
P6179
1009180369