TGF-beta promotion of Gli2-induced expression of parathyroid hormone-related protein, an important osteolytic factor in bone metastasis, is independent of canonical Hedgehog signaling - Wikidata - awgldk - TriplyDB

TGF-beta promotion of Gli2-induced expression of parathyroid hormone-related protein, an important osteolytic factor in bone metastasis, is independent of canonical Hedgehog signaling

TGF-beta promotion of Gli2-induced expression of parathyroid hormone-related protein, an important osteolytic factor in bone metastasis, is independent of canonical Hedgehog signaling

http://www.wikidata.org/entity/Q34796551

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Tamoxifen Resistance: Emerging Molecular Targets The hedgehog pathway in triple-negative breast cancer Hedgehog signaling: modulation of cancer properies and tumor mircroenvironment Hypercalcemia of Malignancy: An Update on Pathogenesis and Management Non-Canonical Hh Signaling in Cancer-Current Understanding and Future Directions The Role of Hedgehog Signaling in Tumor Induced Bone Disease TGF-β/SMAD/GLI2 signaling axis in cancer progression and metastasis Osteoblasts Are the Centerpiece of the Metastatic Bone Microenvironment Switching Roles of TGF-β in Cancer Development: Implications for Therapeutic Target and Biomarker Studies Co-registration of multi-modality imaging allows for comprehensive analysis of tumor-induced bone disease.Epithelial and non-epithelial Ptch1 play opposing roles to regulate proliferation and morphogenesis of the mouse mammary gland Long-term miR-29b suppression reduces aneurysm formation in a Marfan mouse model.Matrix rigidity induces osteolytic gene expression of metastatic breast cancer cells.GANT-61 inhibits pancreatic cancer stem cell growth in vitro and in NOD/SCID/IL2R gamma null mice xenograft Inflammation and Gli2 suppress gastrin gene expression in a murine model of antral hyperplasia Early growth response 4 is involved in cell proliferation of small cell lung cancer through transcriptional activation of its downstream genes Wnt signaling induces gene expression of factors associated with bone destruction in lung and breast cancer.Evaluating the role of PTH in promotion of chondrosarcoma cell proliferation and invasion by inhibiting primary cilia expression.The host microenvironment influences prostate cancer invasion, systemic spread, bone colonization, and osteoblastic metastasis.Gli1 mediates lung cancer cell proliferation and Sonic Hedgehog-dependent mesenchymal cell activation.TGF-β signaling in breast cancer cell invasion and bone metastasis.Down-regulation of Gli transcription factor leads to the inhibition of migration and invasion of ovarian cancer cells via integrin β4-mediated FAK signaling The Wnt inhibitor dickkopf-1: a link between breast cancer and bone metastases.The Role of Sonic Hedgehog Signaling in Osteoclastogenesis and Jaw Bone Destruction.Morphoproteomics provides support for TGF-β pathway signaling in the osteoclastogenesis and immune dysregulation of osteolytic Langerhans cell histiocytosis.Parathyroid hormone-related protein: an update.The Hedgehog pathway: role in cell differentiation, polarity and proliferation Models of bone metastasis.Hedgehog Acyltransferase as a target in estrogen receptor positive, HER2 amplified, and tamoxifen resistant breast cancer cells.Myeloid-derived suppressor cells expand during breast cancer progression and promote tumor-induced bone destruction.Blockade of Autocrine TGF-β Signaling Inhibits Stem Cell Phenotype, Survival, and Metastasis of Murine Breast Cancer Cells.mTORC1 regulates PTHrP to coordinate chondrocyte growth, proliferation and differentiation.Hedgehog signaling inhibition blocks growth of resistant tumors through effects on tumor microenvironment.The Hedgehog signalling pathway in breast development, carcinogenesis and cancer therapy.Expression of parathyroid hormone-related protein confers malignant potential to mucoepidermoid carcinoma The sonic hedgehog pathway mediates brain plasticity and subsequent functional recovery after bone marrow stromal cell treatment of stroke in mice.Targeting hedgehog signaling in cancer: research and clinical developments.Loss of Merlin induces metabolomic adaptation that engages dependence on Hedgehog signaling.Protein kinase inhibitor SU6668 attenuates positive regulation of Gli proteins in cancer and multipotent progenitor cells.Hedgehog and TGFβ signaling converge on Gli2 to control bony invasion and bone destruction in oral squamous cell carcinoma

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P2860

TGF-beta promotion of Gli2-induced expression of parathyroid hormone-related protein, an important osteolytic factor in bone metastasis, is independent of canonical Hedgehog signaling

http://www.wikidata.org/entity/Q34796551

description

2010 nî lūn-bûn

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2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

TGF-beta promotion of Gli2-ind ...... f canonical Hedgehog signaling

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TGF-beta promotion of Gli2-ind ...... f canonical Hedgehog signaling

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TGF-beta promotion of Gli2-ind ...... f canonical Hedgehog signaling

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TGF-beta promotion of Gli2-ind ...... f canonical Hedgehog signaling

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TGF-beta promotion of Gli2-ind ...... f canonical Hedgehog signaling

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TGF-beta promotion of Gli2-ind ...... f canonical Hedgehog signaling

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TGF-beta promotion of Gli2-ind ...... f canonical Hedgehog signaling

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TGF-beta promotion of Gli2-ind ...... f canonical Hedgehog signaling

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TGF-beta promotion of Gli2-ind ...... f canonical Hedgehog signaling

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0008-5472.CAN-10-2993

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Cancer Research

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TGF-beta promotion of Gli2-ind ...... f canonical Hedgehog signaling

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Alyssa R Merkel

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Babatunde O Oyajobi

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Barry G Grubbs

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Gregory R Mundy

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Julie A Sterling

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Lynn M Matrisian

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Mai P Nguyen

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Rachelle W Johnson

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Susan S Padalecki

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P2860

A small molecule that binds Hedgehog and blocks its signaling in human cells

GLI2-specific transcriptional activation of the bone morphogenetic protein/activin antagonist follistatin in human epidermal cells

Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened

Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine

Regulation of Gli2 and Gli3 activities by an amino-terminal repression domain: implication of Gli2 and Gli3 as primary mediators of Shh signaling

Cyclopamine-mediated hedgehog pathway inhibition depletes stem-like cancer cells in glioblastoma

Induction of sonic hedgehog mediators by transforming growth factor-beta: Smad3-dependent activation of Gli2 and Gli1 expression in vitro and in vivo

Cloning of the human GLI2 Promoter: transcriptional activation by transforming growth factor-beta via SMAD3/beta-catenin cooperation.

TGF-beta signaling blockade inhibits PTHrP secretion by breast cancer cells and bone metastases development.

Hedgehog signaling in the normal and neoplastic mammary gland.

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822-831

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10.1158/0008-5472.CAN-10-2993

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3

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2010-12-28T00:00:00Z

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49712717

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21189326

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