A conserved arginine-containing motif crucial for the assembly and enzymatic activity of the mixed lineage leukemia protein-1 core complex.
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Regulation of HOXA2 gene expression by the ATP-dependent chromatin remodeling enzyme CHD8Structural analysis of the KANSL1/WDR5/KANSL2 complex reveals that WDR5 is required for efficient assembly and chromatin targeting of the NSL complexInsights into association of the NuRD complex with FOG-1 from the crystal structure of an RbAp48·FOG-1 complexOn the mechanism of multiple lysine methylation by the human mixed lineage leukemia protein-1 (MLL1) core complexHijacked in cancer: the KMT2 (MLL) family of methyltransferasesOn WD40 proteins: propelling our knowledge of transcriptional control?A role for Set1/MLL-related components in epigenetic regulation of the Caenorhabditis elegans germ lineArabidopsis COMPASS-like complexes mediate histone H3 lysine-4 trimethylation to control floral transition and plant developmentMolecular Mechanism of MLL PHD3 and RNA Recognition by the Cyp33 RRM DomainCharacterization of a Novel WDR5-binding Site That Recruits RbBP5 through a Conserved Motif to Enhance Methylation of Histone H3 Lysine 4 by Mixed Lineage Leukemia Protein-1Binding of different histone marks differentially regulates the activity and specificity of polycomb repressive complex 2 (PRC2)Symmetric dimethylation of H3R2 is a newly identified histone mark that supports euchromatin maintenanceThe plasticity of WDR5 peptide-binding cleft enables the binding of the SET1 family of histone methyltransferasesStructural Basis for WDR5 Interaction (Win) Motif Recognition in Human SET1 Family Histone MethyltransferasesHigh-affinity, small-molecule peptidomimetic inhibitors of MLL1/WDR5 protein-protein interactionTargeted Disruption of the Interaction Between WD-40 Repeat Protein 5 (WDR5) and Mixed Lineage Leukemia (MLL)/SET1 Family Proteins Specifically Inhibits MLL1 and SETd1A Methyltransferase ComplexesA conserved interaction between the SDI domain of Bre2 and the Dpy-30 domain of Sdc1 is required for histone methylation and gene expression.An Ash2L/RbBP5 heterodimer stimulates the MLL1 methyltransferase activity through coordinated substrate interactions with the MLL1 SET domainUsing Lamm-Equation modeling of sedimentation velocity data to determine the kinetic and thermodynamic properties of macromolecular interactions.A non-active-site SET domain surface crucial for the interaction of MLL1 and the RbBP5/Ash2L heterodimer within MLL family core complexesCoordinated chromatin control: structural and functional linkage of DNA and histone methylation.On computational approaches for size-and-shape distributions from sedimentation velocity analytical ultracentrifugation.Mixed lineage leukemia: a structure-function perspective of the MLL1 protein.Fluorescence-based methods for screening writers and readers of histone methyl marks.Substrate and product specificities of SET domain methyltransferasesWRAD: enabler of the SET1-family of H3K4 methyltransferases.Neuronal necrosis is regulated by a conserved chromatin-modifying cascade.Keeping it in the family: diverse histone recognition by conserved structural foldsStructural basis for H3K4 trimethylation by yeast Set1/COMPASS.A novel non-SET domain multi-subunit methyltransferase required for sequential nucleosomal histone H3 methylation by the mixed lineage leukemia protein-1 (MLL1) core complexMyosin5a tail associates directly with Rab3A-containing compartments in neuronsBiochemical reconstitution and phylogenetic comparison of human SET1 family core complexes involved in histone methylationWD repeat-containing protein 5 (WDR5) localizes to the midbody and regulates abscission.Requirement for MLL3 in p53 regulation of hepatic expression of small heterodimer partner and bile acid homeostasis.Charge-based interaction conserved within histone H3 lysine 4 (H3K4) methyltransferase complexes is needed for protein stability, histone methylation, and gene expressionSmall molecules, big targets: drug discovery faces the protein-protein interaction challenge.Unique Role of the WD-40 Repeat Protein 5 (WDR5) Subunit within the Mixed Lineage Leukemia 3 (MLL3) Histone Methyltransferase ComplexThe n-SET domain of Set1 regulates H2B ubiquitylation-dependent H3K4 methylation.Automethylation activities within the mixed lineage leukemia-1 (MLL1) core complex reveal evidence supporting a "two-active site" model for multiple histone H3 lysine 4 methylation.Histone H3K27 trimethylation inhibits H3 binding and function of SET1-like H3K4 methyltransferase complexes.
P2860
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P2860
A conserved arginine-containing motif crucial for the assembly and enzymatic activity of the mixed lineage leukemia protein-1 core complex.
description
2008 nî lūn-bûn
@nan
2008 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
A conserved arginine-containin ...... ukemia protein-1 core complex.
@ast
A conserved arginine-containin ...... ukemia protein-1 core complex.
@en
A conserved arginine-containin ...... ukemia protein-1 core complex.
@nl
type
label
A conserved arginine-containin ...... ukemia protein-1 core complex.
@ast
A conserved arginine-containin ...... ukemia protein-1 core complex.
@en
A conserved arginine-containin ...... ukemia protein-1 core complex.
@nl
prefLabel
A conserved arginine-containin ...... ukemia protein-1 core complex.
@ast
A conserved arginine-containin ...... ukemia protein-1 core complex.
@en
A conserved arginine-containin ...... ukemia protein-1 core complex.
@nl
P2093
P356
P1476
A conserved arginine-containin ...... ukemia protein-1 core complex.
@en
P2093
Anamika Patel
Michael S Cosgrove
Valarie E Vought
Venkatasubramanian Dharmarajan
P304
32162-32175
P356
10.1074/JBC.M806317200
P407
P577
2008-10-01T00:00:00Z