Stalling of spliceosome assembly at distinct stages by small-molecule inhibitors of protein acetylation and deacetylation. - Wikidata - awgldk - TriplyDB

Stalling of spliceosome assembly at distinct stages by small-molecule inhibitors of protein acetylation and deacetylation.

Stalling of spliceosome assembly at distinct stages by small-molecule inhibitors of protein acetylation and deacetylation.

http://www.wikidata.org/entity/Q34887390

about

Modulating splicing with small molecular inhibitors of the spliceosome Prp40 and early events in splice site definition Defects in spliceosomal machinery: a new pathway of leukaemogenesis Functional mammalian spliceosomal complex E contains SMN complex proteins in addition to U1 and U2 snRNPs.Cyclin-Dependent Kinase CRK9, Required for Spliced Leader trans Splicing of Pre-mRNA in Trypanosomes, Functions in a Complex with a New L-Type Cyclin and a Kinetoplastid-Specific Protein Spliceosome Structure and Function Identification of a small molecule inhibitor that stalls splicing at an early step of spliceosome activation.An Ultraconserved Element (UCE) controls homeostatic splicing of ARGLU1 mRNA.A bird's-eye view of post-translational modifications in the spliceosome and their roles in spliceosome dynamics Histone deacetylase activity modulates alternative splicing.Prp8, the pivotal protein of the spliceosomal catalytic center, evolved from a retroelement-encoded reverse transcriptase Psoromic acid derivatives: a new family of small-molecule pre-mRNA splicing inhibitors discovered by a stage-specific high-throughput in vitro splicing assay.Spliceostatin A inhibits spliceosome assembly subsequent to prespliceosome formation.Tetracyclines that promote SMN2 exon 7 splicing as therapeutics for spinal muscular atrophy.The anti-tumor drug E7107 reveals an essential role for SF3b in remodeling U2 snRNP to expose the branch point-binding region.Motor neuron disease. SMN2 splicing modifiers improve motor function and longevity in mice with spinal muscular atrophy.Identification of small molecule inhibitors of pre-mRNA splicing.A quantitative high-throughput in vitro splicing assay identifies inhibitors of spliceosome catalysis.Ionizing radiation induces immediate protein acetylation changes in human cardiac microvascular endothelial cells High-throughput single-molecule screen for small-molecule perturbation of splicing and transcription kinetics.ATPγS stalls splicing after B complex formation but prior to spliceosome activation.Small Molecule Modulators of Pre-mRNA Splicing in Cancer Therapy The Proteomic Profile of Deleted in Breast Cancer 1 (DBC1) Interactions Points to a Multifaceted Regulation of Gene Expression Valproic acid treatment from the 4-cell stage improves Oct4 expression and nuclear distribution of histone H3K27me3 in mouse cloned blastocysts.Unraveling the role of peptidyl-prolyl isomerases in neurodegeneration.Diverse regulation of 3' splice site usage.Linking functions: an additional role for an intrinsically disordered linker domain in the transcriptional coactivator CBP.Alternative splicing: the pledge, the turn, and the prestige : The key role of alternative splicing in human biological systems.Mapping the binding site of snurportin 1 on native U1 snRNP by cross-linking and mass spectrometry.Reduced fidelity of branch point recognition and alternative splicing induced by the anti-tumor drug spliceostatin A The transition in spliceosome assembly from complex E to complex A purges surplus U1 snRNPs from alternative splice sites.Molecular architecture of zinc chelating small molecules that inhibit spliceosome assembly at an early stage.Association of feature gene expression with structural fingerprints of chemical compounds.Characterization of barley Prp1 gene and its expression during seed development and under abiotic stress.Intron specificity in pre-mRNA splicing.HIV latency reversing agents act through Tat post translational modifications.Novel histone deacetylase inhibitors and embryo aggregation enhance cloned embryo development and ES cell derivation in pigs

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P2860

Stalling of spliceosome assembly at distinct stages by small-molecule inhibitors of protein acetylation and deacetylation.

http://www.wikidata.org/entity/Q34887390

description

2008 nî lūn-bûn

@nan

2008 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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name

Stalling of spliceosome assemb ...... acetylation and deacetylation.

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Stalling of spliceosome assemb ...... acetylation and deacetylation.

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Stalling of spliceosome assemb ...... acetylation and deacetylation.

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Stalling of spliceosome assemb ...... acetylation and deacetylation.

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Stalling of spliceosome assemb ...... acetylation and deacetylation.

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Stalling of spliceosome assemb ...... acetylation and deacetylation.

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Stalling of spliceosome assemb ...... acetylation and deacetylation.

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Stalling of spliceosome assemb ...... acetylation and deacetylation.

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Stalling of spliceosome assemb ...... acetylation and deacetylation.

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Stalling of spliceosome assemb ...... acetylation and deacetylation.

@en

P2093

Andreas N Kuhn

http://www.w3.org/2001/XMLSchema#string

Andreas Schwienhorst

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Henning Urlaub

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Maria A van Santen

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P2860

The p68 and p72 DEAD box RNA helicases interact with HDAC1 and repress transcription in a promoter-specific manner

The flavoring agent dihydrocoumarin reverses epigenetic silencing and inhibits sirtuin deacetylases

Human STAGA complex is a chromatin-acetylating transcription coactivator that interacts with pre-mRNA splicing and DNA damage-binding factors in vivo

Negative control of p53 by Sir2alpha promotes cell survival under stress

A subset of human 35S U5 proteins, including Prp19, function prior to catalytic step 1 of splicing

Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis.

Composition and three-dimensional EM structure of double affinity-purified, human prespliceosomal A complexes

CDK11 complexes promote pre-mRNA splicing

p68 RNA helicase is an essential human splicing factor that acts at the U1 snRNA-5' splice site duplex.

Large-scale proteomic analysis of the human spliceosome

P304

153-175

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scholarly article

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10.1261/RNA.1332609

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1

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15

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Reinhard Georg Lührmann

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2008-11-24T00:00:00Z

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23493207

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19029308

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P932

2612777

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