SORCS1 alters amyloid precursor protein processing and variants may increase Alzheimer's disease risk. - Wikidata - awgldk - TriplyDB

SORCS1 alters amyloid precursor protein processing and variants may increase Alzheimer's disease risk.

SORCS1 alters amyloid precursor protein processing and variants may increase Alzheimer's disease risk.

http://www.wikidata.org/entity/Q34914826

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Human-specific histone methylation signatures at transcription start sites in prefrontal neurons Role of the Retromer Complex in Neurodegenerative Diseases Insights into obesity and diabetes at the intersection of mouse and human genetics Preclinical Alzheimer disease: identification of cases at risk among cognitively intact older individuals The location and trafficking routes of the neuronal retromer and its role in amyloid precursor protein transport Sortilin Fragments Deposit at Senile Plaques in Human Cerebrum Impact of genetic variation in SORCS1 on memory retention.SORCS1 is necessary for normal insulin secretory granule biogenesis in metabolically stressed β cells.The genetic variation of SORCS1 is associated with late-onset Alzheimer's disease in Chinese Han population.Apomorphine and Alzheimer Aβ: roles for regulated α cleavage, autophagy, and antioxidation?The role of the retromer complex in aging-related neurodegeneration: a molecular and genomic review.The "Alzheimer's disease signature": potential perspectives for novel biomarkers.Diabetes-associated SorCS1 regulates Alzheimer's amyloid-beta metabolism: evidence for involvement of SorL1 and the retromer complex.Both common variations and rare non-synonymous substitutions and small insertion/deletions in CLU are associated with increased Alzheimer risk.A genome-wide scan for common variants affecting the rate of age-related cognitive decline.Alzheimer's disease and the amyloid cascade hypothesis: a critical review.Alzheimer's disease: a clinical practice-oriented review.Epidemiology of Alzheimer disease.Candidate genes for Alzheimer's disease are associated with individual differences in plasma levels of beta amyloid peptides in adults with Down syndrome.Identification of Alzheimer disease-associated variants in genes that regulate retromer function The role of intracellular trafficking and the VPS10d receptors in Alzheimer's disease.Dyslipidemia and the risk of Alzheimer's disease.Unexpected partial correction of metabolic and behavioral phenotypes of Alzheimer's APP/PSEN1 mice by gene targeting of diabetes/Alzheimer's-related Sorcs1 Vps10 family proteins and the retromer complex in aging-related neurodegeneration and diabetes.Recalculation of 23 mouse HDL QTL datasets improves accuracy and allows for better candidate gene analysis.Independent and epistatic effects of variants in VPS10-d receptors on Alzheimer disease risk and processing of the amyloid precursor protein (APP)Dyslipidemia and dementia: current epidemiology, genetic evidence, and mechanisms behind the associations.Protein sorting motifs in the cytoplasmic tail of SorCS1 control generation of Alzheimer's amyloid-β peptide Neuropathology of Autosomal Dominant Alzheimer Disease in the National Alzheimer Coordinating Center Database.SORCS1 contributes to the development of renal disease in rats and humans.SORL1 mutations in early- and late-onset Alzheimer disease.Genetics of Alzheimer's disease in Caribbean Hispanic and African American populations.Comparing GWAS Results of Complex Traits Using Full Genetic Model and Additive Models for Revealing Genetic Architecture.Retromers in Alzheimer's disease.Informatics Support for Basic Research in Biomedicine.The Role of Retromer in Alzheimer's Disease.A Greek Tragedy: The Growing Complexity of Alzheimer Amyloid Precursor Protein Proteolysis.SorLA complement-type repeat domains protect the amyloid precursor protein against processing.In vitro screen of prion disease susceptibility genes using the scrapie cell assay.Secreted amyloid precursor proteins promote proliferation and glial differentiation of adult hippocampal neural progenitor cells.

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SORCS1 alters amyloid precursor protein processing and variants may increase Alzheimer's disease risk.

http://www.wikidata.org/entity/Q34914826

description

2011 nî lūn-bûn

@nan

2011 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի հունվարին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

SORCS1 alters amyloid precurso ...... ease Alzheimer's disease risk.

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SORCS1 alters amyloid precurso ...... ease Alzheimer's disease risk.

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SORCS1 alters amyloid precurso ...... ease Alzheimer's disease risk.

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SORCS1 alters amyloid precurso ...... ease Alzheimer's disease risk.

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SORCS1 alters amyloid precurso ...... ease Alzheimer's disease risk.

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SORCS1 alters amyloid precurso ...... ease Alzheimer's disease risk.

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SORCS1 alters amyloid precurso ...... ease Alzheimer's disease risk.

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SORCS1 alters amyloid precurso ...... ease Alzheimer's disease risk.

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SORCS1 alters amyloid precurso ...... ease Alzheimer's disease risk.

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Annals of Neurology

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SORCS1 alters amyloid precurso ...... ease Alzheimer's disease risk.

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András Palotás

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Badri Vardarajan

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Christopher Conrad

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Irene Simkin

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Ivonne Z Jiménez-Velázquez

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Jean-Paul Vonsattel

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Lili-Naz Hazrati

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Lorraine N Clark

http://www.w3.org/2001/XMLSchema#string

Martin Medrano

http://www.w3.org/2001/XMLSchema#string

Raphael Lantigua

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P2860

The allelic architecture of human disease genes: common disease-common variant... or not?

SORL1 variants and risk of late-onset Alzheimer's disease

Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and betaAPP processing

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.

The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease

CDD: a conserved domain database for interactive domain family analysis

Measuring inconsistency in meta-analyses

Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease

Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro

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47-64

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10.1002/ANA.22308

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1

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69

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Margaret A. Pericak-Vance

Ekaterina Rogaeva

Lindsay A. Farrer

Christiane Reitz

Peter Henry St George-Hyslop

Jonathan L Haines

P577

2011-01-01T00:00:00Z

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49797292

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21280075

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Alzheimer's disease

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3086759

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