An anti-PR1/HLA-A2 T-cell receptor-like antibody mediates complement-dependent cytotoxicity against acute myeloid leukemia progenitor cells.
about
T cell receptor mimic antibodies for cancer therapyEvaluation of current cancer immunotherapy: hemato-oncologyAdoptive T-cell therapy for LeukemiaTherapeutic bispecific T-cell engager antibody targeting the intracellular oncoprotein WT1.Immune Effector Recovery in Chronic Myeloid Leukemia and Treatment-Free Remission.Strategies to genetically engineer T cells for cancer immunotherapy.A TCR-mimic antibody to WT1 bypasses tyrosine kinase inhibitor resistance in human BCR-ABL+ leukemiasTherapeutic efficacy of an Fc-enhanced TCR-like antibody to the intracellular WT1 oncoprotein.Characterization of immunologic properties of a second HLA-A2 epitope from a granule protease in CML patients and HLA-A2 transgenic miceAffinity maturation of T-cell receptor-like antibodies for Wilms tumor 1 peptide greatly enhances therapeutic potential.Building better monoclonal antibody-based therapeutics.The role of antigen cross-presentation from leukemia blasts on immunity to the leukemia-associated antigen PR1.Breast cancer cell uptake of the inflammatory mediator neutrophil elastase triggers an anticancer adaptive immune responseBroad cross-presentation of the hematopoietically derived PR1 antigen on solid tumors leads to susceptibility to PR1-targeted immunotherapy.Dissecting graft-versus-leukemia from graft-versus-host-disease using novel strategiesActivity of 8F4, a T-cell receptor-like anti-PR1/HLA-A2 antibody, against primary human AML in vivoApproaching untargetable tumor-associated antigens with antibodies.CAR T cells for acute myeloid leukemia: the LeY of the land.Targeting Epstein-Barr virus-transformed B lymphoblastoid cells using antibodies with T-cell receptor-like specificitiesDendritic cell-based immunotherapy for myeloid leukemias.Cathepsin G is broadly expressed in acute myeloid leukemia and is an effective immunotherapeutic target.Targeting the intracellular WT1 oncogene product with a therapeutic human antibody.TCR-like biomolecules target peptide/MHC Class I complexes on the surface of infected and cancerous cells.T-cell-receptor-like antibodies - generation, function and applications.Neuropilin-1 mediates neutrophil elastase uptake and cross-presentation in breast cancer cells.A therapeutic T cell receptor mimic antibody targets tumor-associated PRAME peptide/HLA-I antigens.An immunogenic WT1-derived peptide that induces T cell response in the context of HLA-A*02:01 and HLA-A*24:02 molecules.A novel TCR-like CAR with specificity for PR1/HLA-A2 effectively targets myeloid leukemia in vitro when expressed in human adult peripheral blood and cord blood T cellsOpportunities and challenges for TCR mimic antibodies in cancer therapyA role for BMP-induced homeobox gene MIXL1 in acute myelogenous leukemia and identification of type I BMP receptor as a potential target for therapy.Therapeutic targeting of naturally presented myeloperoxidase-derived HLA peptide ligands on myeloid leukemia cells by TCR-transgenic T cells.Retargeting NK-92 for anti-melanoma activity by a TCR-like single-domain antibody.A novel HLA-A*0201 restricted peptide derived from cathepsin G is an effective immunotherapeutic target in acute myeloid leukemia.PR1-specific cytotoxic T lymphocytes are relatively frequent in umbilical cord blood and can be effectively expanded to target myeloid leukemia.TCR-like antibodies mediate complement and antibody-dependent cellular cytotoxicity against Epstein-Barr virus-transformed B lymphoblastoid cells expressing different HLA-A*02 microvariants.Targeting cathepsin G in myeloid leukemia.Therapeutic Antibodies against Intracellular Tumor AntigensTargeting myelogenous leukemia stem cells: role of the circulation.Construction and molecular characterization of a T-cell receptor-like antibody and CAR-T cells specific for minor histocompatibility antigen HA-1H.Acute myeloid leukaemia.
P2860
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P2860
An anti-PR1/HLA-A2 T-cell receptor-like antibody mediates complement-dependent cytotoxicity against acute myeloid leukemia progenitor cells.
description
2011 nî lūn-bûn
@nan
2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
An anti-PR1/HLA-A2 T-cell rece ...... oid leukemia progenitor cells.
@ast
An anti-PR1/HLA-A2 T-cell rece ...... oid leukemia progenitor cells.
@en
An anti-PR1/HLA-A2 T-cell rece ...... oid leukemia progenitor cells.
@nl
type
label
An anti-PR1/HLA-A2 T-cell rece ...... oid leukemia progenitor cells.
@ast
An anti-PR1/HLA-A2 T-cell rece ...... oid leukemia progenitor cells.
@en
An anti-PR1/HLA-A2 T-cell rece ...... oid leukemia progenitor cells.
@nl
prefLabel
An anti-PR1/HLA-A2 T-cell rece ...... oid leukemia progenitor cells.
@ast
An anti-PR1/HLA-A2 T-cell rece ...... oid leukemia progenitor cells.
@en
An anti-PR1/HLA-A2 T-cell rece ...... oid leukemia progenitor cells.
@nl
P2093
P2860
P921
P1433
P1476
An anti-PR1/HLA-A2 T-cell rece ...... oid leukemia progenitor cells.
@en
P2093
Anna Sergeeva
Bradley W McIntyre
Gheath Alatrash
James Wygant
Jeffrey J Molldrem
Karen Clise-Dwyer
Kathryn Ruisaard
Lisa St John
P2860
P304
P356
10.1182/BLOOD-2010-07-299248
P407
P577
2011-02-04T00:00:00Z