Validation of transgenic mice carrying the human prototype c-Ha-ras gene as a bioassay model for rapid carcinogenicity testing
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The role of transgenic mouse models in carcinogen identificationUse of transgenic animals for carcinogenicity testing: considerations and implications for risk assessment.Use of DNA repair-deficient XPA transgenic mice in short-term carcinogenicity testing.Utilization of genetically altered animals in the pharmaceutical industry.Assessing the potential carcinogenic activity of magnetic fields using animal models.Detection of the onset of ischemia and carcinogenesis by hypoxia-inducible transcription factor-based in vivo bioluminescence imagingAnimal models used in identifying gender-related differences.Historical control data of spontaneous tumors in transgenic CByB6F1-Tg(HRAS)2Jic (Tg.rasH2) mice.The Tg rasH2 mouse in cancer hazard identification.Identification of mammary carcinogens in rodent bioassays.The use of genetically modified mice in cancer risk assessment: challenges and limitations.A tiered approach to systemic toxicity testing for agricultural chemical safety assessment.Final amended report on the safety assessment of oxyquinoline and oxyquinoline sulfate as used in cosmetics.Current Status of Short-Term Tests for Evaluation of Genotoxicity, Mutagenicity, and Carcinogenicity of Environmental Chemicals and NCEs.A further review of inhalation studies with cigarette smoke and lung cancer in experimental animals, including transgenic mice.Establishing a laboratory animal model from a transgenic animal: RasH2 mice as a model for carcinogenicity studies in regulatory science.Twenty-six-week oral carcinogenicity study of 3-monochloropropane-1,2-diol in CB6F1-rasH2 transgenic mice.Regulatory Forum commentary: alternative mouse models for future cancer risk assessment.Hematopoietic proliferative lesions in the spleen of rasH2 transgenic mice treated with MNU.A mechanistic study of ovarian carcinogenesis induced by nitrofurazone using rasH2 mice.High frequency of ras mutations in forestomach and lung tumors of B6C3F1 mice exposed to 1-amino-2,4-dibromoanthraquinone for 2 years.Di(2-ethylhexyl)phthalate induces hepatocellular adenoma in transgenic mice carrying a human prototype c-Ha-ras gene in a 26-week carcinogenicity study.Mutation and overexpression of the transgene in ethylnitrosourea-induced tumors in mice carrying a human prototype c-Ha-ras gene.Effect of oral gavage dosing regimens in female Tg rasH2 transgenic mice.Scientific Opinion on the use of Resorcinol as a food additiveRelationship of body weight parameters with the incidence of common spontaneous tumors in Tg.rasH2 mice.Reduction in the number of animals and the evaluation period for the positive control group in Tg.rasH2 short-term carcinogenicity studies.An integrative test strategy for cancer hazard identification.Possible application of human c-Ha-ras proto-oncogene transgenic rats in a medium-term bioassay model for carcinogens.Tumor promotion by 12-O-tetradecanoylphorbol-13-acetate in an ultra-short-term skin carcinogenesis bioassay using rasH2 mice.Transgenic rats carrying copies of the human c-Ha-ras proto-oncogene exhibit enhanced susceptibility to N-butyl-N-(4-hydroxybutyl)nitrosamine bladder carcinogenesis.Pathological features of spontaneous and induced tumors in transgenic mice carrying a human prototype c-Ha-ras gene used for six-month carcinogenicity studies.
P2860
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P2860
Validation of transgenic mice carrying the human prototype c-Ha-ras gene as a bioassay model for rapid carcinogenicity testing
description
1998 nî lūn-bûn
@nan
1998 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Validation of transgenic mice ...... rapid carcinogenicity testing
@ast
Validation of transgenic mice ...... rapid carcinogenicity testing
@en
Validation of transgenic mice ...... rapid carcinogenicity testing
@nl
type
label
Validation of transgenic mice ...... rapid carcinogenicity testing
@ast
Validation of transgenic mice ...... rapid carcinogenicity testing
@en
Validation of transgenic mice ...... rapid carcinogenicity testing
@nl
prefLabel
Validation of transgenic mice ...... rapid carcinogenicity testing
@ast
Validation of transgenic mice ...... rapid carcinogenicity testing
@en
Validation of transgenic mice ...... rapid carcinogenicity testing
@nl
P2093
P2860
P356
P1476
Validation of transgenic mice ...... rapid carcinogenicity testing
@en
P2093
S Yamamoto
Y Kurokawa
P2860
P356
10.1289/EHP.98106S157
P478
106 Suppl 1
P577
1998-02-01T00:00:00Z