about
Sphingolipids: a potential molecular approach to treat allergic inflammationRegulation of the Hippo-YAP pathway by G-protein-coupled receptor signalingCrystal structure of a lipid G protein-coupled receptorThe role of sphingosine-1-phosphate transporter Spns2 in immune system functionSphingosine 1-phosphate lyase, a key regulator of sphingosine 1-phosphate signaling and functionThe SphKs/S1P/S1PR1 axis in immunity and cancer: more ore to be minedThe role of sphingosine-1-phosphate in endothelial barrier functionThe compartmentalization and translocation of the sphingosine kinases: mechanisms and functions in cell signaling and sphingolipid metabolismEndogenous lipid activated G protein-coupled receptors: emerging structural features from crystallography and molecular dynamics simulationsSphingosine-1-phosphate receptor 1 signalling in T cells: trafficking and beyondThe adipokine/ceramide axis: key aspects of insulin sensitizationMoesin controls clathrin-mediated S1PR1 internalization in T cellsEnhancement of neoangiogenesis and follicle survival by sphingosine-1-phosphate in human ovarian tissue xenotransplantsOcean acidification affects redox-balance and ion-homeostasis in the life-cycle stages of Emiliania huxleyiIntracellular S1P generation is essential for S1P-induced motility of human lung endothelial cells: role of sphingosine kinase 1 and S1P lyaseTransforming Sphingosine Kinase 1 Inhibitors into Dual and Sphingosine Kinase 2 Selective Inhibitors: Design, Synthesis, and in Vivo Activity.Sphingosine-1-Phosphate Receptor-3 Supports Hematopoietic Stem and Progenitor Cell Residence Within the Bone Marrow Niche.Sphingosine kinase inhibitors decrease viability and induce cell death in natural killer-large granular lymphocyte leukemia.Acid sphingomyelinase is activated in sickle cell erythrocytes and contributes to inflammatory microparticle generation in SCD.Sphingosine 1-phosphate enhances the excitability of rat sensory neurons through activation of sphingosine 1-phosphate receptors 1 and/or 3A metabolic shift favoring sphingosine 1-phosphate at the expense of ceramide controls glioblastoma angiogenesis.Pharmacological tools for lysophospholipid GPCRs: development of agonists and antagonists for LPA and S1P receptors.Development of amidine-based sphingosine kinase 1 nanomolar inhibitors and reduction of sphingosine 1-phosphate in human leukemia cells.Differential involvement of ezrin/radixin/moesin proteins in sphingosine 1-phosphate-induced human pulmonary endothelial cell barrier enhancementSphingosine-1-phosphate as an amphipathic metabolite: its properties in aqueous and membrane environments4-Methoxy-N-[2-(trifluoromethyl)biphenyl-4-ylcarbamoyl]nicotinamide: A Potent and Selective Agonist of S1P1.Discovery of a Potent, S1P3-Sparing Benzothiazole Agonist of Sphingosine-1-Phosphate Receptor 1 (S1P1)Discovery of AMG 369, a Thiazolo[5,4-b]pyridine Agonist of S1P1 and S1P5.Optimization of a Potent, Orally Active S1P1 Agonist Containing a Quinolinone Core.Re-configuration of sphingolipid metabolism by oncogenic transformation.Animal model of respiratory syncytial virus: CD8+ T cells cause a cytokine storm that is chemically tractable by sphingosine-1-phosphate 1 receptor agonist therapy.HDL3, but not HDL2, stimulates plasminogen activator inhibitor-1 release from adipocytes: the role of sphingosine-1-phosphate.Mouse SPNS2 functions as a sphingosine-1-phosphate transporter in vascular endothelial cellsMembranes in balance: mechanisms of sphingolipid homeostasis.The sphingosine 1-phosphate receptor, S1PR₁, plays a prominent but not exclusive role in enhancing the excitability of sensory neurons.An update on sphingosine-1-phosphate and other sphingolipid mediators.T-lymphoblastic lymphoma cells express high levels of BCL2, S1P1, and ICAM1, leading to a blockade of tumor cell intravasation.Sphingosine-1-phosphate and immune regulation: trafficking and beyondSphingosine 1-phosphate mediates hyperalgesia via a neutrophil-dependent mechanism.Role for peroxynitrite in sphingosine-1-phosphate-induced hyperalgesia in rats
P2860
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P2860
description
2009 nî lūn-bûn
@nan
2009 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Sphingosine 1-phosphate receptor signaling.
@ast
Sphingosine 1-phosphate receptor signaling.
@en
Sphingosine 1-phosphate receptor signaling.
@nl
type
label
Sphingosine 1-phosphate receptor signaling.
@ast
Sphingosine 1-phosphate receptor signaling.
@en
Sphingosine 1-phosphate receptor signaling.
@nl
prefLabel
Sphingosine 1-phosphate receptor signaling.
@ast
Sphingosine 1-phosphate receptor signaling.
@en
Sphingosine 1-phosphate receptor signaling.
@nl
P2093
P1476
Sphingosine 1-phosphate receptor signaling.
@en
P2093
Hugh Rosen
M Germana Sanna
Pedro J Gonzalez-Cabrera
Steven Brown
P304
P356
10.1146/ANNUREV.BIOCHEM.78.072407.103733
P577
2009-01-01T00:00:00Z