Multiple point mutations in a shuttle vector propagated in human cells: evidence for an error-prone DNA polymerase activity.
about
Multiple mutations and frameshifts are the hallmark of defective hPMS2 in pZ189-transfected human tumor cellsThe mutational spectrum of non-CpG DNA varies with CpG contentAltered spectra of hypermutation in antibodies from mice deficient for the DNA mismatch repair protein PMS2Evidence of ultraviolet type mutations in xeroderma pigmentosum melanomas.Joining of linear plasmid DNA is reduced and error-prone in Bloom's syndrome cells.Effects of exonuclease activity and nucleotide selectivity of the herpes simplex virus DNA polymerase on the fidelity of DNA replication in vivo.Mutagenic specificity of a potent carcinogen, benzo[c]phenanthrene (4R,3S)-dihydrodiol (2S,1R)-epoxide, which reacts with adenine and guanine in DNA.Conversion of normal to malignant phenotype: telomere shortening, telomerase activation, and genomic instability during immortalization of human oral keratinocytes.Oncogenic potential is related to activating effect of cancer single and double somatic mutations in receptor tyrosine kinasesHypermutability in carcinogenesisDeletions at short direct repeats and base substitutions are characteristic mutations for bleomycin-induced double- and single-strand breaks, respectively, in a human shuttle vector system.UV and skin cancer: specific p53 gene mutation in normal skin as a biologically relevant exposure measurementA role for sunlight in skin cancer: UV-induced p53 mutations in squamous cell carcinoma.Abnormal ultraviolet mutagenic spectrum in plasmid DNA replicated in cultured fibroblasts from a patient with the skin cancer-prone disease, xeroderma pigmentosumMechanism of abnormal elastin gene expression in the pinguecular part of pterygia.Evolutionary switches between two serine codon sets are driven by selection.The repertoire of somatic antibody mutants accumulating in the memory compartment after primary immunization is restricted through affinity maturation and mirrors that expressed in the secondary responseRapid and apparently error-prone excision repair of nonreplicating UV-irradiated plasmids in Xenopus laevis oocytesLinked spontaneous CG----TA mutations at CpG sites in the gene for protein kinase regulatory subunitDetermination of the spectrum of mutations induced by defined-wavelength solar UVB (313-nm) radiation in mammalian cells by use of a shuttle vectorMutation in a reporter gene depends on proximity to and transcription of immunoglobulin variable transgenes.Xeroderma pigmentosum variant cells are less likely than normal cells to incorporate dAMP opposite photoproducts during replication of UV-irradiated plasmidsReplication fidelity of the supF gene integrated in the thymidine kinase locus of herpes simplex virus type 1.Cr(III)-mediated crosslinks of glutathione or amino acids to the DNA phosphate backbone are mutagenic in human cells.Singlet oxygen induced mutation spectrum in mammalian cells.Accuracy of intrachromosomal gene conversion in mouse cells.Heteroduplex-induced mutagenesis in mammalian cells.The fidelity of HPV16 E1/E2-mediated DNA replication.Characterization of mutant spectra generated by a forward mutational assay for gene A of Phi X174 from ENU-treated transgenic mouse embryonic cell line PX-2.Alteration of irradiated shuttle vector processing by exposure of human lymphoblast host cells to single or split gamma-ray doses.Multiple dispersed spontaneous mutations: a novel pathway of mutation in a malignant human cell line
P2860
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P2860
Multiple point mutations in a shuttle vector propagated in human cells: evidence for an error-prone DNA polymerase activity.
description
1987 nî lūn-bûn
@nan
1987 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1987 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1987年の論文
@ja
1987年論文
@yue
1987年論文
@zh-hant
1987年論文
@zh-hk
1987年論文
@zh-mo
1987年論文
@zh-tw
1987年论文
@wuu
name
Multiple point mutations in a ...... prone DNA polymerase activity.
@ast
Multiple point mutations in a ...... prone DNA polymerase activity.
@en
Multiple point mutations in a ...... prone DNA polymerase activity.
@nl
type
label
Multiple point mutations in a ...... prone DNA polymerase activity.
@ast
Multiple point mutations in a ...... prone DNA polymerase activity.
@en
Multiple point mutations in a ...... prone DNA polymerase activity.
@nl
prefLabel
Multiple point mutations in a ...... prone DNA polymerase activity.
@ast
Multiple point mutations in a ...... prone DNA polymerase activity.
@en
Multiple point mutations in a ...... prone DNA polymerase activity.
@nl
P2093
P2860
P356
P1476
Multiple point mutations in a ...... prone DNA polymerase activity.
@en
P2093
A Bredberg
K H Kraemer
M M Seidman
S Seetharam
P2860
P304
P356
10.1073/PNAS.84.14.4944
P407
P577
1987-07-01T00:00:00Z