Pathogenesis of herpes simplex virus type 2 virion host shutoff (vhs) mutants.
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mRNA decay during herpes simplex virus (HSV) infections: protein-protein interactions involving the HSV virion host shutoff protein and translation factors eIF4H and eIF4A.Shutoff of Host Gene Expression in Influenza A Virus and Herpesviruses: Similar Mechanisms and Common ThemesInfluenza A Virus Protein PA-X Contributes to Viral Growth and Suppression of the Host Antiviral and Immune ResponsesRNA-dependent protein kinase is required for alpha-1 interferon transgene-induced resistance to genital herpes simplex virus type 2.Herpes simplex virus type 2 UL24 gene is a virulence determinant in murine and guinea pig disease models.The virion host shutoff endonuclease (UL41) of herpes simplex virus interacts with the cellular cap-binding complex eIF4F.Oncolytic herpes simplex virus 1 encoding 15-prostaglandin dehydrogenase mitigates immune suppression and reduces ectopic primary and metastatic breast cancer in mice.Efficient generation and rapid isolation via stoplight recombination of Herpes simplex viruses expressing model antigenic and immunological epitopes.Herpes simplex virus type 2 virion host shutoff protein regulates alpha/beta interferon but not adaptive immune responses during primary infection in vivo.B7 costimulation molecules expressed from the herpes simplex virus 2 genome rescue immune induction in B7-deficient miceTo replicate or not to replicate: achieving selective oncolytic virus replication in cancer cells through translational control.Selective ablation of virion host shutoff protein RNase activity attenuates herpes simplex virus 2 in mice.mRNA decay during herpes simplex virus (HSV) infections: mutations that affect translation of an mRNA influence the sites at which it is cleaved by the HSV virion host shutoff (Vhs) protein.Truncation of C-terminal 20 amino acids in PA-X contributes to adaptation of swine influenza virus in pigs.Enhanced pathogenesis of an attenuated herpes simplex virus for mice lacking Stat1Small interfering RNAs that deplete the cellular translation factor eIF4H impede mRNA degradation by the virion host shutoff protein of herpes simplex virusGender-dependent HLA-DR-restricted epitopes identified from herpes simplex virus type 1 glycoprotein D.Herpes simplex virus downregulates secretory leukocyte protease inhibitor: a novel immune evasion mechanismThe herpes simplex virus 1 UL41 gene-dependent destabilization of cellular RNAs is selective and may be sequence-specific.Regulation of endothelial progenitor cell release by Wnt signaling in bone marrow.Type I IFN response to Papiine herpesvirus 2 (Herpesvirus papio 2; HVP2) determines neuropathogenicity in mice.New concepts in herpes simplex virus vaccine development: notes from the battlefield.A two-pronged strategy to suppress host protein synthesis by SARS coronavirus Nsp1 protein.RNA degradation induced by the herpes simplex virus vhs protein proceeds 5' to 3' in vitro.Phosphorylation of a herpes simplex virus 1 dUTPase by a viral protein kinase, Us3, dictates viral pathogenicity in the central nervous system but not at the periphery.Role of the VP16-binding domain of vhs in viral growth, host shutoff activity, and pathogenesis.Exploiting human herpesvirus immune evasion for therapeutic gain: potential and pitfalls.Virus-encoded endonucleases: expected and novel functions.Herpes simplex virus virion host shutoff attenuates establishment of the antiviral state.The amino terminus of the herpes simplex virus 1 protein Vhs mediates membrane association and tegument incorporation.The herpes simplex virus 1 vhs protein enhances translation of viral true late mRNAs and virus production in a cell type-dependent manner.The Splicing History of an mRNA Affects Its Level of Translation and Sensitivity to Cleavage by the Virion Host Shutoff Endonuclease during Herpes Simplex Virus InfectionsEvidence for translational regulation by the herpes simplex virus virion host shutoff proteinThe virion host shutoff protein of herpes simplex virus type 1 has RNA degradation activity in primary neurons.Role of the virion host shutoff protein in neurovirulence of monkey B virus (Macacine herpesvirus 1).Increased eIF2alpha phosphorylation attenuates replication of herpes simplex virus 2 vhs mutants in mouse embryonic fibroblasts and correlates with reduced accumulation of the PKR antagonist ICP34.5.Proinflammatory cytokines and chemokines - but not interferon-β - produced in response to HSV-2 in primary human genital epithelial cells are associated with viral replication and the presence of the virion host shutoff protein.Herpesviruses: Harmonious Pathogens but Relevant Cofactors in Other Diseases?Multiple post-transcriptional strategies to regulate the herpes simplex virus type 1 vhs endoribonucleaseA bimodal switch in global protein translation coupled to eIF4H relocalisation during advancing cell-cell transmission of herpes simplex virus
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P2860
Pathogenesis of herpes simplex virus type 2 virion host shutoff (vhs) mutants.
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2002 nî lūn-bûn
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2002 թուականի Մարտին հրատարակուած գիտական յօդուած
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2002 թվականի մարտին հրատարակված գիտական հոդված
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2002年の論文
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2002年論文
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2002年論文
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2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
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name
Pathogenesis of herpes simplex virus type 2 virion host shutoff (vhs) mutants.
@ast
Pathogenesis of herpes simplex virus type 2 virion host shutoff (vhs) mutants.
@en
Pathogenesis of herpes simplex virus type 2 virion host shutoff
@nl
type
label
Pathogenesis of herpes simplex virus type 2 virion host shutoff (vhs) mutants.
@ast
Pathogenesis of herpes simplex virus type 2 virion host shutoff (vhs) mutants.
@en
Pathogenesis of herpes simplex virus type 2 virion host shutoff
@nl
prefLabel
Pathogenesis of herpes simplex virus type 2 virion host shutoff (vhs) mutants.
@ast
Pathogenesis of herpes simplex virus type 2 virion host shutoff (vhs) mutants.
@en
Pathogenesis of herpes simplex virus type 2 virion host shutoff
@nl
P2093
P2860
P1433
P1476
Pathogenesis of herpes simplex virus type 2 virion host shutoff (vhs) mutants.
@en
P2093
David A Leib
Lynda A Morrison
Tracy J Smith
P2860
P304
P356
10.1128/JVI.76.5.2054-2061.2002
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P577
2002-03-01T00:00:00Z