A two-pronged strategy to suppress host protein synthesis by SARS coronavirus Nsp1 protein.
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Regulation of Stress Responses and Translational Control by CoronavirusA Tale of Two RNAs during Viral Infection: How Viruses Antagonize mRNAs and Small Non-Coding RNAs in The Host CellCoronavirus virulence genes with main focus on SARS-CoV envelope geneStructure of Alphacoronavirus Transmissible Gastroenteritis Virus nsp1 Has Implications for Coronavirus nsp1 Function and EvolutionQuantitative proteomics analysis reveals BAG3 as a potential target to suppress severe acute respiratory syndrome coronavirus replicationViral and Cellular mRNA Translation in Coronavirus-Infected Cells.Dependence of coronavirus RNA replication on an NH2-terminal partial nonstructural protein 1 in cis.The SARS-coronavirus-host interactome: identification of cyclophilins as target for pan-coronavirus inhibitorsCoordinated destruction of cellular messages in translation complexes by the gammaherpesvirus host shutoff factor and the mammalian exonuclease Xrn1.SARS coronavirus nsp1 protein induces template-dependent endonucleolytic cleavage of mRNAs: viral mRNAs are resistant to nsp1-induced RNA cleavageBinding of the 5'-untranslated region of coronavirus RNA to zinc finger CCHC-type and RNA-binding motif 1 enhances viral replication and transcriptionNuclear import of cytoplasmic poly(A) binding protein restricts gene expression via hyperadenylation and nuclear retention of mRNA.Alphacoronavirus transmissible gastroenteritis virus nsp1 protein suppresses protein translation in mammalian cells and in cell-free HeLa cell extracts but not in rabbit reticulocyte lysateCoronaviruses: an overview of their replication and pathogenesis.Single-dose intranasal administration with mDEF201 (adenovirus vectored mouse interferon-alpha) confers protection from mortality in a lethal SARS-CoV BALB/c mouse modelAttenuation of mouse hepatitis virus by deletion of the LLRKxGxKG region of Nsp1.Identification of residues of SARS-CoV nsp1 that differentially affect inhibition of gene expression and antiviral signaling.Strategies for viral RNA stability: live long and prosperImportin alpha-mediated nuclear import of cytoplasmic poly(A) binding protein occurs as a direct consequence of cytoplasmic mRNA depletionSwitch from cap- to factorless IRES-dependent 0 and +1 frame translation during cellular stress and dicistrovirus infection.Dissection of amino-terminal functional domains of murine coronavirus nonstructural protein 3.Coronavirus nonstructural protein 1: Common and distinct functions in the regulation of host and viral gene expression.Highly Pathogenic New World and Old World Human Arenaviruses Induce Distinct Interferon Responses in Human Cells.Transcriptome-Wide Cleavage Site Mapping on Cellular mRNAs Reveals Features Underlying Sequence-Specific Cleavage by the Viral Ribonuclease SOX.Genetic evidence of a long-range RNA-RNA interaction between the genomic 5' untranslated region and the nonstructural protein 1 coding region in murine and bovine coronavirusesSelective Degradation of Host RNA Polymerase II Transcripts by Influenza A Virus PA-X Host Shutoff Protein.Middle East Respiratory Syndrome Coronavirus nsp1 Inhibits Host Gene Expression by Selectively Targeting mRNAs Transcribed in the Nucleus while Sparing mRNAs of Cytoplasmic OriginIdentification of the Mechanisms Causing Reversion to Virulence in an Attenuated SARS-CoV for the Design of a Genetically Stable Vaccine.Severe acute respiratory syndrome coronavirus nsp1 facilitates efficient propagation in cells through a specific translational shutoff of host mRNA.Extensive Positive Selection Drives the Evolution of Nonstructural Proteins in Lineage C Betacoronaviruses.Interplay between viruses and host mRNA degradationThe structural and accessory proteins M, ORF 4a, ORF 4b, and ORF 5 of Middle East respiratory syndrome coronavirus (MERS-CoV) are potent interferon antagonistsAlphacoronavirus protein 7 modulates host innate immune response.Reselection of a genomic upstream open reading frame in mouse hepatitis coronavirus 5'-untranslated-region mutantsViral tricks to grid-lock the type I interferon system.Viruses and the cellular RNA decay machinery.Biogenesis and dynamics of the coronavirus replicative structures.Tinkering with translation: protein synthesis in virus-infected cells.MERS-CoV papain-like protease has deISGylating and deubiquitinating activities.Emerging roles for RNA degradation in viral replication and antiviral defense.
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A two-pronged strategy to suppress host protein synthesis by SARS coronavirus Nsp1 protein.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 18 October 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
A two-pronged strategy to supp ...... SARS coronavirus Nsp1 protein.
@en
A two-pronged strategy to supp ...... SARS coronavirus Nsp1 protein.
@nl
type
label
A two-pronged strategy to supp ...... SARS coronavirus Nsp1 protein.
@en
A two-pronged strategy to supp ...... SARS coronavirus Nsp1 protein.
@nl
prefLabel
A two-pronged strategy to supp ...... SARS coronavirus Nsp1 protein.
@en
A two-pronged strategy to supp ...... SARS coronavirus Nsp1 protein.
@nl
P2860
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P356
P1476
A two-pronged strategy to supp ...... SARS coronavirus Nsp1 protein.
@en
P2093
Krishna Narayanan
Wataru Kamitani
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P2888
P304
P356
10.1038/NSMB.1680
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2009-10-18T00:00:00Z