The FANC pathway and BLM collaborate during mitosis to prevent micro-nucleation and chromosome abnormalities. - Wikidata - awgldk - TriplyDB

The FANC pathway and BLM collaborate during mitosis to prevent micro-nucleation and chromosome abnormalities.

The FANC pathway and BLM collaborate during mitosis to prevent micro-nucleation and chromosome abnormalities.

http://www.wikidata.org/entity/Q34982804

about

FANCI binds branched DNA and is monoubiquitinated by UBE2T-FANCL ATM-dependent expression of IEX-1 controls nuclear accumulation of Mcl-1 and the DNA damage response Interaction between the helicases genetically linked to Fanconi anemia group J and Bloom's syndrome Molecular pathogenesis and clinical management of Fanconi anemia Susceptibility pathways in Fanconi's anemia and breast cancer How the fanconi anemia pathway guards the genome Maintaining Genome Stability in Defiance of Mitotic DNA Damage Interplay between Fanconi anemia and homologous recombination pathways in genome integrity Fanconi anemia and the cell cycle: new perspectives on aneuploidy Replication stress in early S phase generates apparent micronuclei and chromosome rearrangement in fission yeast.The Fanconi Anemia C Protein Binds to and Regulates Stathmin-1 Phosphorylation TopBP1/Dpb11 binds DNA anaphase bridges to prevent genome instability.Replication stress in Mammalian cells and its consequences for mitosis Initiation of genome instability and preneoplastic processes through loss of Fhit expression Loss of GGN leads to pre-implantation embryonic lethality and compromised male meiotic DNA double strand break repair in the mouse Expanded roles of the Fanconi anemia pathway in preserving genomic stability Cytokinesis failure occurs in Fanconi anemia pathway-deficient murine and human bone marrow hematopoietic cells The relative efficiency of homology-directed repair has distinct effects on proper anaphase chromosome separation.On the regulation, function, and localization of the DNA-dependent ATPase PICH.Papillomavirus genomes associate with BRD4 to replicate at fragile sites in the host genome.Defective endomitosis during megakaryopoiesis leads to thrombocytopenia in Fanca-/- mice.A concomitant loss of dormant origins and FANCC exacerbates genome instability by impairing DNA replication fork progression.Fanca deficiency reduces A/T transitions in somatic hypermutation and alters class switch recombination junctions in mouse B cells.Fanconi anemia signaling and Mus81 cooperate to safeguard development and crosslink repair Molecular mechanisms of micronucleus, nucleoplasmic bridge and nuclear bud formation in mammalian and human cells.PICH and BLM limit histone association with anaphase centromeric DNA threads and promote their resolution.Human CST promotes telomere duplex replication and general replication restart after fork stalling.PICH: a DNA translocase specially adapted for processing anaphase bridge DNA.DNA double strand breaks but not interstrand crosslinks prevent progress through meiosis in fully grown mouse oocytes.Topoisomerase II- and condensin-dependent breakage of MEC1ATR-sensitive fragile sites occurs independently of spindle tension, anaphase, or cytokinesis.TRF1 negotiates TTAGGG repeat-associated replication problems by recruiting the BLM helicase and the TPP1/POT1 repressor of ATR signaling.Rescue from replication stress during mitosis.FANC pathway promotes UV-induced stalled replication forks recovery by acting both upstream and downstream Polη and Rev1.ERCC1 function in nuclear excision and interstrand crosslink repair pathways is mediated exclusively by the ERCC1-202 isoform Re-examination of siRNA specificity questions role of PICH and Tao1 in the spindle checkpoint and identifies Mad2 as a sensitive target for small RNAs.The Fanconi anemia pathway and ICL repair: implications for cancer therapy.Lac operator repeats generate a traceable fragile site in mammalian cells Cyclin E deregulation promotes loss of specific genomic regions.Fanconi anemia and Bloom's syndrome crosstalk through FANCJ-BLM helicase interaction.Rescue of replication failure by Fanconi anaemia proteins.

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The FANC pathway and BLM collaborate during mitosis to prevent micro-nucleation and chromosome abnormalities.

http://www.wikidata.org/entity/Q34982804

description

2009 nî lūn-bûn

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2009 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2009 թվականի մայիսին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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The FANC pathway and BLM colla ...... and chromosome abnormalities.

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The FANC pathway and BLM colla ...... and chromosome abnormalities.

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The FANC pathway and BLM colla ...... and chromosome abnormalities.

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The FANC pathway and BLM colla ...... and chromosome abnormalities.

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The FANC pathway and BLM colla ...... and chromosome abnormalities.

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The FANC pathway and BLM colla ...... and chromosome abnormalities.

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The FANC pathway and BLM colla ...... and chromosome abnormalities.

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The FANC pathway and BLM colla ...... and chromosome abnormalities.

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The FANC pathway and BLM colla ...... and chromosome abnormalities.

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Nature Cell Biology

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The FANC pathway and BLM colla ...... and chromosome abnormalities.

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Filippo Rosselli

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Valeria Naim

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P2860

Human BUBR1 is a mitotic checkpoint kinase that monitors CENP-E functions at kinetochores and binds the cyclosome/APC

Architecture of the human ndc80-hec1 complex, a critical constituent of the outer kinetochore

The Bloom's syndrome gene product is homologous to RecQ helicases

A multiprotein nuclear complex connects Fanconi anemia and Bloom syndrome

Chk1-mediated phosphorylation of FANCE is required for the Fanconi anemia/BRCA pathway

The Fanconi anaemia/BRCA pathway

Interaction of the Fanconi anemia proteins and BRCA1 in a common pathway

Cancer-susceptibility genes. Gatekeepers and caretakers

The BRCA1/BARD1 heterodimer modulates ran-dependent mitotic spindle assembly

Histone H2AX and Fanconi anemia FANCD2 function in the same pathway to maintain chromosome stability

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761-768

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10.1038/NCB1883

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6

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11

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2009-05-24T00:00:00Z

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1034751837

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19465921

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