A role for FEN-1 in nonhomologous DNA end joining: the order of strand annealing and nucleolytic processing events.
about
Epigenetic changes of DNA repair genes in cancerThe role of DNA polymerase activity in human non-homologous end joiningWerner syndrome protein interacts with human flap endonuclease 1 and stimulates its cleavage activityWRN helicase and FEN-1 form a complex upon replication arrest and together process branchmigrating DNA structures associated with the replication forkMolecular structure and novel DNA binding sites located in loops of flap endonuclease-1 from Pyrococcus horikoshiiInhibition of proteasomal degradation of rpn4 impairs nonhomologous end-joining repair of DNA double-strand breaks.Genetic interactions between HNT3/Aprataxin and RAD27/FEN1 suggest parallel pathways for 5' end processing during base excision repairThe yeast chromatin remodeler RSC complex facilitates end joining repair of DNA double-strand breaksA physical and functional interaction between yeast Pol4 and Dnl4-Lif1 links DNA synthesis and ligation in nonhomologous end joining.Efficient processing of DNA ends during yeast nonhomologous end joining. Evidence for a DNA polymerase beta (Pol4)-dependent pathway.Evidence for a role of FEN1 in maintaining mitochondrial DNA integrityProcessing and joining of DNA ends coordinated by interactions among Dnl4/Lif1, Pol4, and FEN-1.Processing of damaged DNA ends for double-strand break repair in mammalian cellsThe biochemistry and biological significance of nonhomologous DNA end joining: an essential repair process in multicellular eukaryotesPhosphorylation of human Fen1 by cyclin-dependent kinase modulates its role in replication fork regulationRegulatory interactions between the checkpoint kinase Chk1 and the proteins of the DNA-dependent protein kinase complexFlap endonuclease 1 is overexpressed in prostate cancer and is associated with a high Gleason scoreDNA joint dependence of pol X family polymerase action in nonhomologous end joiningModulation of DNA end joining by nuclear proteinsGenetic instability in budding and fission yeast-sources and mechanismsDNA damage response genes and the development of cancer metastasisProliferation failure and gamma radiation sensitivity of Fen1 null mutant mice at the blastocyst stageIdentification of flap structure-specific endonuclease 1 as a factor involved in long-term memory formation of aversive learningFlap endonuclease-1 rs174538 G>A polymorphisms are associated with the risk of esophageal cancer in a Chinese populationNonhomologous DNA end joining in cell-free systems.Novel function of Rad27 (FEN-1) in restricting short-sequence recombination.Haploinsufficiency of Flap endonuclease (Fen1) leads to rapid tumor progressionKinetics of endogenous mouse FEN1 in base excision repair.The role of replication bypass pathways in dicentric chromosome formation in budding yeastTargeting abnormal DNA double strand break repair in cancerThe DNA-protein interaction modes of FEN-1 with gap substrates and their implication in preventing duplication mutations.End-processing during non-homologous end-joining: a role for exonuclease 1Genetic analyses of Schizosaccharomyces pombe dna2(+) reveal that dna2 plays an essential role in Okazaki fragment metabolism.Differential suppression of DNA repair deficiencies of Yeast rad50, mre11 and xrs2 mutants by EXO1 and TLC1 (the RNA component of telomerase).Human Fanconi anemia complementation group a protein stimulates the 5' flap endonuclease activity of FEN1.Two modes of FEN1 binding to PCNA regulated by DNA.Yeast recombination pathways triggered by topoisomerase II-mediated DNA breaks.Nuclease-deficient FEN-1 blocks Rad51/BRCA1-mediated repair and causes trinucleotide repeat instabilityThe SET Domain Is Essential for Metnase Functions in Replication Restart and the 5' End of SS-Overhang Cleavage.The role of the non-homologous end-joining pathway in lymphocyte development.
P2860
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P2860
A role for FEN-1 in nonhomologous DNA end joining: the order of strand annealing and nucleolytic processing events.
description
1999 nî lūn-bûn
@nan
1999 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
A role for FEN-1 in nonhomolog ...... nucleolytic processing events.
@ast
A role for FEN-1 in nonhomolog ...... nucleolytic processing events.
@en
A role for FEN-1 in nonhomolog ...... nucleolytic processing events.
@nl
type
label
A role for FEN-1 in nonhomolog ...... nucleolytic processing events.
@ast
A role for FEN-1 in nonhomolog ...... nucleolytic processing events.
@en
A role for FEN-1 in nonhomolog ...... nucleolytic processing events.
@nl
prefLabel
A role for FEN-1 in nonhomolog ...... nucleolytic processing events.
@ast
A role for FEN-1 in nonhomolog ...... nucleolytic processing events.
@en
A role for FEN-1 in nonhomolog ...... nucleolytic processing events.
@nl
P2093
P2860
P356
P1476
A role for FEN-1 in nonhomolog ...... nucleolytic processing events.
@en
P2093
P2860
P304
P356
10.1073/PNAS.96.4.1303
P407
P577
1999-02-01T00:00:00Z