Differential interleukin-6/Stat3 signaling as a function of cellular context mediates Ras-induced transformation - Wikidata - awgldk - TriplyDB

Differential interleukin-6/Stat3 signaling as a function of cellular context mediates Ras-induced transformation

Differential interleukin-6/Stat3 signaling as a function of cellular context mediates Ras-induced transformation

http://www.wikidata.org/entity/Q34989115

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The Role of the Transcriptional Regulation of Stromal Cells in Chronic Inflammation STAT3 negatively regulates thyroid tumorigenesis Identifying and quantifying heterogeneity in high content analysis: application of heterogeneity indices to drug discovery Il-6 signaling between ductal carcinoma in situ cells and carcinoma-associated fibroblasts mediates tumor cell growth and migration STAT3 knockdown reduces pancreatic cancer cell invasiveness and matrix metalloproteinase-7 expression in nude mice.Permissiveness of human cancer cells to oncolytic bovine herpesvirus 1 is mediated in part by KRAS activity The transcriptional responsiveness of LKB1 to STAT-mediated signaling is differentially modulated by prolactin in human breast cancer cells.Stat3 mediates expression of autotaxin in breast cancer STAT3 is activated by JAK2 independent of key oncogenic driver mutations in non-small cell lung carcinoma.The need for complex 3D culture models to unravel novel pathways and identify accurate biomarkers in breast cancer Negative regulation of STAT3 protein-mediated cellular respiration by SIRT1 protein.3D culture broadly regulates tumor cell hypoxia response and angiogenesis via pro-inflammatory pathways.Stat3: friend or foe in colitis and colitis-associated cancer?Mesenchymal Cell Reprogramming in Experimental MPLW515L Mouse Model of Myelofibrosis.Sphingosine-1-phosphate in inflammatory bowel disease and colitis-associated colon cancer: the fat's in the fire The IL-6/JAK/Stat3 feed-forward loop drives tumorigenesis and metastasis.STAT3 as a new autophagy regulator.Interleukin-6 cytokine: a multifunctional glycoprotein for cancer.Autophagy-dependent production of secreted factors facilitates oncogenic RAS-driven invasion.PI3K and STAT3: a new alliance.The role of intratumoral and systemic IL-6 in breast cancer.How should we define STAT3 as an oncogene and as a potential target for therapy?STK11/LKB1 Deficiency Promotes Neutrophil Recruitment and Proinflammatory Cytokine Production to Suppress T-cell Activity in the Lung Tumor Microenvironment.RNAi-mediated silencing of Anxa2 inhibits breast cancer cell proliferation by downregulating cyclin D1 in STAT3-dependent pathway.An optical labeling-based proliferation assay system reveals the paracrine effect of interleukin-6 in breast cancer.Phosphorylated STAT3 physically interacts with NPM and transcriptionally enhances its expression in cancer.Tanshinone IIA inhibits breast cancer stem cells growth in vitro and in vivo through attenuation of IL-6/STAT3/NF-kB signaling pathways.Towards automated production and drug sensitivity testing using scaffold-free spherical tumor microtissues.Oncogenic Ras induces inflammatory cytokine production by upregulating the squamous cell carcinoma antigens SerpinB3/B4.Screening Active Compounds from Garcinia Species Native to China Reveals Novel Compounds Targeting the STAT/JAK Signaling Pathway.KIF5B-RET fusion kinase promotes cell growth by multilevel activation of STAT3 in lung cancer.3D culture reveals a signaling network.SH003 suppresses breast cancer growth by accumulating p62 in autolysosomes.Interleukin 6 gene polymorphism -174 is associated with the diffuse type gastric carcinoma.Interleukin-6 and Interferon-α Signaling via JAK1-STAT Differentially Regulate Oncolytic versus Cytoprotective Antiviral States.

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Differential interleukin-6/Stat3 signaling as a function of cellular context mediates Ras-induced transformation

http://www.wikidata.org/entity/Q34989115

description

2010 nî lūn-bûn

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2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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Differential interleukin-6/Sta ...... tes Ras-induced transformation

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Differential interleukin-6/Sta ...... tes Ras-induced transformation

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Differential interleukin-6/Sta ...... tes Ras-induced transformation

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Differential interleukin-6/Sta ...... tes Ras-induced transformation

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Differential interleukin-6/Sta ...... tes Ras-induced transformation

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Hao Ho

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Jacqueline Bromberg

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Katrina Podsypanina

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Kenneth Leslie

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Lionel Ivashkiv

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Sizhi P Gao

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CBP Is a dosage-dependent regulator of nuclear factor-kappaB suppression by the estrogen receptor

IL-6 triggers malignant features in mammospheres from human ductal breast carcinoma and normal mammary gland

Mutations in the EGFR kinase domain mediate STAT3 activation via IL-6 production in human lung adenocarcinomas

Activation of estrogen receptor blocks interleukin-6-inducible cell growth of human multiple myeloma involving molecular cross-talk between estrogen receptor and STAT3 mediated by co-regulator PIAS3

Proteins regulating Ras and its relatives

Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation

Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures

STATs and gene regulation

The STATs of cancer--new molecular targets come of age

Stat3 as an oncogene

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10.1186/BCR2725

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5

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12

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3096973

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