Interaction between the RNA binding domains of Ser-Arg splicing factor 1 and U1-70K snRNP protein determines early spliceosome assembly. - Wikidata - awgldk - TriplyDB

Interaction between the RNA binding domains of Ser-Arg splicing factor 1 and U1-70K snRNP protein determines early spliceosome assembly.

Interaction between the RNA binding domains of Ser-Arg splicing factor 1 and U1-70K snRNP protein determines early spliceosome assembly.

http://www.wikidata.org/entity/Q35002838

about

RNA-Binding Proteins: Splicing Factors and Disease Connecting the speckles: Splicing kinases and their role in tumorigenesis and treatment response Phosphorylation-mediated regulation of alternative splicing in cancer Isolated pseudo-RNA-recognition motifs of SR proteins can regulate splicing using a noncanonical mode of RNA recognition Molecular mechanisms for the regulation of histone mRNA stem-loop-binding protein by phosphorylation.Context-dependent control of alternative splicing by RNA-binding proteins The significant other: splicing by the minor spliceosome Conserved proline-directed phosphorylation regulates SR protein conformation and splicing function Whole-Exome Sequencing Identifies Loci Associated with Blood Cell Traits and Reveals a Role for Alternative GFI1B Splice Variants in Human Hematopoiesis.The alternative heart: impact of alternative splicing in heart disease.Both decreased and increased SRPK1 levels promote cancer by interfering with PHLPP-mediated dephosphorylation of Akt.Emerging functions of SRSF1, splicing factor and oncoprotein, in RNA metabolism and cancer.Ceramide modulates pre-mRNA splicing to restore the expression of wild-type tumor suppressor p53 in deletion-mutant cancer cells.The RNAissance family: SR proteins as multifaceted regulators of gene expression Role of Acinus in regulating retinoic acid-responsive gene pre-mRNA splicing.Detained introns are a novel, widespread class of post-transcriptionally spliced introns.Loss of nuclear TDP-43 in amyotrophic lateral sclerosis (ALS) causes altered expression of splicing machinery and widespread dysregulation of RNA splicing in motor neurones.Structural basis for regulation of RNA-binding proteins by phosphorylation.The SRSF1 linker induces semi-conservative ESE binding by cooperating with the RRMs.Activation and repression functions of an SR splicing regulator depend on exonic versus intronic-binding position Intra-domain Cross-talk Regulates Serine-arginine Protein Kinase 1-dependent Phosphorylation and Splicing Function of Transformer 2β1 A U1-U2 snRNP interaction network during intron definition Increased Serine-Arginine (SR) Protein Phosphorylation Changes Pre-mRNA Splicing in Hypoxia.The Activation-Induced Assembly of an RNA/Protein Interactome Centered on the Splicing Factor U2AF2 Regulates Gene Expression in Human CD4 T Cells Prp4 Kinase Grants the License to Splice: Control of Weak Splice Sites during Spliceosome Activation SRSF1 and hnRNP H antagonistically regulate splicing of COLQ exon 16 in a congenital myasthenic syndrome The Akt-SRPK-SR axis constitutes a major pathway in transducing EGF signaling to regulate alternative splicing in the nucleus.Position-dependent splicing activation and repression by SR and hnRNP proteins rely on common mechanisms.Alternative splicing modulated by genetic variants demonstrates accelerated evolution regulated by highly conserved proteins Therapeutic activity of modified U1 core spliceosomal particles A U1 snRNP-specific assembly pathway reveals the SMN complex as a versatile hub for RNP exchange N-terminus of the protein kinase CLK1 induces SR protein hyperphosphorylation Partitioning RS domain phosphorylation in an SR protein through the CLK and SRPK protein kinases.The spliceosome: disorder and dynamics defined.Pick one, but be quick: 5' splice sites and the problems of too many choices.Regulation of splicing by SR proteins and SR protein-specific kinases.A day in the life of the spliceosome Normal and aberrant splicing of LMNA.SR protein kinases promote splicing of nonconsensus introns.A targeted oligonucleotide enhancer of SMN2 exon 7 splicing forms competing quadruplex and protein complexes in functional conditions.

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Interaction between the RNA binding domains of Ser-Arg splicing factor 1 and U1-70K snRNP protein determines early spliceosome assembly.

http://www.wikidata.org/entity/Q35002838

description

2011 nî lūn-bûn

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2011 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2011 թվականի մայիսին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

Interaction between the RNA bi ...... es early spliceosome assembly.

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Interaction between the RNA bi ...... es early spliceosome assembly.

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type

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Interaction between the RNA bi ...... es early spliceosome assembly.

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Interaction between the RNA bi ...... es early spliceosome assembly.

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Interaction between the RNA bi ...... es early spliceosome assembly.

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Interaction between the RNA bi ...... es early spliceosome assembly.

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PNAS.1017700108

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Interaction between the RNA bi ...... es early spliceosome assembly.

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Amy Hoang

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Gourisankar Ghosh

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Rahul Sinha

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Suhyung Cho

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Xiang-Dong Fu

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Xiang-Yang Zhong

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P2860

Phosphorylation-dephosphorylation differentially affects activities of splicing factor ASF/SF2.

Both phosphorylation and dephosphorylation of ASF/SF2 are required for pre-mRNA splicing in vitro.

Identification of functional exonic splicing enhancer motifs recognized by individual SR proteins

Processive phosphorylation of alternative splicing factor/splicing factor 2

SR proteins in vertical integration of gene expression from transcription to RNA processing to translation

The spliceosome: design principles of a dynamic RNP machine

Mechanisms of alternative pre-messenger RNA splicing

Dephosphorylated SRp38 acts as a splicing repressor in response to heat shock

Protein-protein interactions and 5'-splice-site recognition in mammalian mRNA precursors

Mass spectrometric and kinetic analysis of ASF/SF2 phosphorylation by SRPK1 and Clk/Sty

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Adrian Robert Krainer

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