Processive phosphorylation of alternative splicing factor/splicing factor 2 - Wikidata - awgldk - TriplyDB

Processive phosphorylation of alternative splicing factor/splicing factor 2

Processive phosphorylation of alternative splicing factor/splicing factor 2

http://www.wikidata.org/entity/Q24647623

about

The enzymatic activity of SR protein kinases 1 and 1a is negatively affected by interaction with scaffold attachment factors B1 and 2 A sliding docking interaction is essential for sequential and processive phosphorylation of an SR protein by SRPK1 Phosphorylation mechanism and structure of serine-arginine protein kinases Adaptable molecular interactions guide phosphorylation of the SR protein ASF/SF2 by SRPK1 Splicing Regulators and Their Roles in Cancer Biology and Therapy Structural basis for nuclear import of splicing factors by human Transportin 3 Inhibition of the SR protein-phosphorylating CLK kinases of Plasmodium falciparum impairs blood stage replication and malaria transmission Mass spectrometric and kinetic analysis of ASF/SF2 phosphorylation by SRPK1 and Clk/Sty Structurally unique yeast and mammalian serine-arginine protein kinases catalyze evolutionarily conserved phosphorylation reactions Applying the brakes to multisite SR protein phosphorylation: substrate-induced effects on the splicing kinase SRPK1 PfSRPK1, a novel splicing-related kinase from Plasmodium falciparum Programming with models: modularity and abstraction provide powerful capabilities for systems biology.Identification of a nuclear localization motif in the serine/arginine protein kinase PSRPK of physarum polycephalum.Bruchpilot in ribbon-like axonal agglomerates, behavioral defects, and early death in SRPK79D kinase mutants of Drosophila.Substrate and docking interactions in serine/threonine protein kinases Full-length hepatitis B virus core protein packages viral and heterologous RNA with similarly high levels of cooperativity Emerging functions of SRSF1, splicing factor and oncoprotein, in RNA metabolism and cancer.A kinase chaperones hepatitis B virus capsid assembly and captures capsid dynamics in vitro.Regulated cellular partitioning of SR protein-specific kinases in mammalian cells Regulation of alternative splicing by reversible protein phosphorylation.Interaction between the RNA binding domains of Ser-Arg splicing factor 1 and U1-70K snRNP protein determines early spliceosome assembly.Regulating SR protein phosphorylation through regions outside the kinase domain of SRPK1 Statistics of cellular signal transduction as a race to the nucleus by multiple random walkers in compartment/phosphorylation space.Monitoring processivity and length control of a carbohydrate polymerase.Intra-domain Cross-talk Regulates Serine-arginine Protein Kinase 1-dependent Phosphorylation and Splicing Function of Transformer 2β1 The distribution of phosphorylated SR proteins and alternative splicing are regulated by RANBP2 Increased Serine-Arginine (SR) Protein Phosphorylation Changes Pre-mRNA Splicing in Hypoxia.A proposed signaling motif for nuclear import in mRNA processing via the formation of arginine claw.Processive phosphorylation: mechanism and biological importance The Akt-SRPK-SR axis constitutes a major pathway in transducing EGF signaling to regulate alternative splicing in the nucleus.Evolutionary constraints associated with functional specificity of the CMGC protein kinases MAPK, CDK, GSK, SRPK, DYRK, and CK2alpha.Individual Cas phosphorylation sites are dispensable for processive phosphorylation by Src and anchorage-independent cell growth Nucleotide release sequences in the protein kinase SRPK1 accelerate substrate phosphorylation.Topical antiangiogenic SRPK1 inhibitors reduce choroidal neovascularization in rodent models of exudative AMD SRPK1 Dissimilarly Impacts on the Growth, Metastasis, Chemosensitivity and Angiogenesis of Glioma in Normoxic and Hypoxic Conditions.Partitioning RS domain phosphorylation in an SR protein through the CLK and SRPK protein kinases.Post-translational modification: nature's escape from genetic imprisonment and the basis for dynamic information encoding.Regulation of splicing by SR proteins and SR protein-specific kinases.Catalytic mechanisms and regulation of protein kinases.SR protein kinases promote splicing of nonconsensus introns.

P2860

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P2860

Processive phosphorylation of alternative splicing factor/splicing factor 2

http://www.wikidata.org/entity/Q24647623

description

2003 nî lūn-bûn

@nan

2003 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2003 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

2003年の論文

@ja

2003年論文

@yue

2003年論文

@zh-hant

2003年論文

@zh-hk

2003年論文

@zh-mo

2003年論文

@zh-tw

2003年论文

@wuu

name

Processive phosphorylation of alternative splicing factor/splicing factor 2

@ast

Processive phosphorylation of alternative splicing factor/splicing factor 2

@en

Processive phosphorylation of alternative splicing factor/splicing factor 2

@nl

type

label

Processive phosphorylation of alternative splicing factor/splicing factor 2

@ast

Processive phosphorylation of alternative splicing factor/splicing factor 2

@en

Processive phosphorylation of alternative splicing factor/splicing factor 2

@nl

prefLabel

Processive phosphorylation of alternative splicing factor/splicing factor 2

@ast

Processive phosphorylation of alternative splicing factor/splicing factor 2

@en

Processive phosphorylation of alternative splicing factor/splicing factor 2

@nl

P1433

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P932

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P356

PNAS.1635129100

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Processive phosphorylation of alternative splicing factor/splicing factor 2

@en

P2093

Brad Nolen

http://www.w3.org/2001/XMLSchema#string

Brandon E Aubol

http://www.w3.org/2001/XMLSchema#string

Gourisankar Ghosh

http://www.w3.org/2001/XMLSchema#string

Jacky Ngo

http://www.w3.org/2001/XMLSchema#string

Jennifer Shaffer

http://www.w3.org/2001/XMLSchema#string

Joseph A Adams

http://www.w3.org/2001/XMLSchema#string

Sutapa Chakrabarti

http://www.w3.org/2001/XMLSchema#string

Xiang-Dong Fu

http://www.w3.org/2001/XMLSchema#string

P2860

The subcellular localization of SF2/ASF is regulated by direct interaction with SR protein kinases (SRPKs)

The Clk2 and Clk3 dual-specificity protein kinases regulate the intranuclear distribution of SR proteins and influence pre-mRNA splicing

SRPK2: a differentially expressed SR protein-specific kinase involved in mediating the interaction and localization of pre-mRNA splicing factors in mammalian cells

A serine kinase regulates intracellular localization of splicing factors in the cell cycle

Phosphorylation-dephosphorylation differentially affects activities of splicing factor ASF/SF2.

Both phosphorylation and dephosphorylation of ASF/SF2 are required for pre-mRNA splicing in vitro.

Sorting out the complexity of SR protein functions

Transportin-SR2 mediates nuclear import of phosphorylated SR proteins

The Clk/Sty protein kinase phosphorylates SR splicing factors and regulates their intranuclear distribution

The structure of Sky1p reveals a novel mechanism for constitutive activity

P304

12601-6

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1073/PNAS.1635129100

http://www.w3.org/2001/XMLSchema#string

P407

P433

22

http://www.w3.org/2001/XMLSchema#string

P478

100

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P577

2003-10-28T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

5465592

http://www.w3.org/2001/XMLSchema#string

P698

14555757

http://www.w3.org/2001/XMLSchema#string

P921

phosphorylation

P932

240664

http://www.w3.org/2001/XMLSchema#string