SQSTM1/p62 interacts with HDAC6 and regulates deacetylase activity. - Wikidata - awgldk - TriplyDB

SQSTM1/p62 interacts with HDAC6 and regulates deacetylase activity.

SQSTM1/p62 interacts with HDAC6 and regulates deacetylase activity.

http://www.wikidata.org/entity/Q35006130

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HDAC signaling in neuronal development and axon regeneration A Role for the Chaperone Complex BAG3-HSPB8 in Actin Dynamics, Spindle Orientation and Proper Chromosome Segregation during Mitosis Exploring new pathways of neurodegeneration in ALS: the role of mitochondria quality control p62 links the autophagy pathway and the ubiqutin-proteasome system upon ubiquitinated protein degradation Mito-xenophagic killing of bacteria is coordinated by a metabolic switch in dendritic cells Interaction of SQSTM1 with the motor protein dynein--SQSTM1 is required for normal dynein function and trafficking.Reserve autophagic capacity in alveolar epithelia provides a replicative niche for influenza A virus.Autophagy restricts HIV-1 infection by selectively degrading Tat in CD4+ T lymphocytes.Pharmacologic agents targeting autophagy.aPKC phosphorylation of HDAC6 results in increased deacetylation activity Metformin increases degradation of phospholamban via autophagy in cardiomyocytes The autophagy GABARAPL1 gene is epigenetically regulated in breast cancer models Potassium Bisperoxo(1,10-phenanthroline)oxovanadate (bpV(phen)) Induces Apoptosis and Pyroptosis and Disrupts the P62-HDAC6 Protein Interaction to Suppress the Acetylated Microtubule-dependent Degradation of Autophagosomes.HDAC6 activity is not required for basal autophagic flux in metastatic prostate cancer cells.Chronic heart failure: Ca(2+), catabolism, and catastrophic cell death.The fine-tuning of proteolytic pathways in Alzheimer's disease.Mitochondrial and lysosomal biogenesis are activated following PINK1/parkin-mediated mitophagy.Stress granules at the intersection of autophagy and ALS.Targeting the integrated networks of aggresome formation, proteasome, and autophagy potentiates ER stress‑mediated cell death in multiple myeloma cells.Inhibition of HDAC6 activity through interaction with RanBPM and its associated CTLH complex.ISGylation - a key to lock the cell gates for preventing the spread of threats.The role of the selective adaptor p62 and ubiquitin-like proteins in autophagy.Both p62/SQSTM1-HDAC6-dependent autophagy and the aggresome pathway mediate CDK1 degradation in human breast cancer Reversible Keap1 inhibitors are preferential pharmacological tools to modulate cellular mitophagy.Tauopathy induced by low level expression of a human brain-derived tau fragment in mice is rescued by phenylbutyrate.Histone Deacetylase Inhibitor-Induced Autophagy in Tumor Cells: Implications for p53.Evolution of tools and methods for monitoring autophagic flux in mammalian cells.HDAC6 controls innate immune and autophagy responses to TLR-mediated signalling by the intracellular bacteria Listeria monocytogenes.Metastatic prostate cancer-associated P62 inhibits autophagy flux and promotes epithelial to mesenchymal transition by sustaining the level of HDAC6.HDAC6 Inhibition Promotes Transcription Factor EB Activation and Is Protective in Experimental Kidney Disease.p53-Mediated Molecular Control of Autophagy in Tumor Cells.Molecular responses to therapeutic proteasome inhibitors in multiple myeloma patients are donor-, cell type- and drug-dependent.TRIM50 suppressed hepatocarcinoma progression through directly targeting SNAIL for ubiquitous degradation.Emergence of Members of TRAF and DUB of Ubiquitin Proteasome System in the Regulation of Hypertrophic Cardiomyopathy

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P2860

SQSTM1/p62 interacts with HDAC6 and regulates deacetylase activity.

http://www.wikidata.org/entity/Q35006130

description

2013 nî lūn-bûn

@nan

2013 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2013 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2013年の論文

@ja

2013年論文

@yue

2013年論文

@zh-hant

2013年論文

@zh-hk

2013年論文

@zh-mo

2013年論文

@zh-tw

2013年论文

@wuu

name

SQSTM1/p62 interacts with HDAC6 and regulates deacetylase activity.

@ast

SQSTM1/p62 interacts with HDAC6 and regulates deacetylase activity.

@en

type

label

SQSTM1/p62 interacts with HDAC6 and regulates deacetylase activity.

@ast

SQSTM1/p62 interacts with HDAC6 and regulates deacetylase activity.

@en

prefLabel

SQSTM1/p62 interacts with HDAC6 and regulates deacetylase activity.

@ast

SQSTM1/p62 interacts with HDAC6 and regulates deacetylase activity.

@en

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JOURNAL.PONE.0076016

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P1476

SQSTM1/p62 interacts with HDAC6 and regulates deacetylase activity.

@en

P2093

Jin Yan

http://www.w3.org/2001/XMLSchema#string

Jorge Moscat

http://www.w3.org/2001/XMLSchema#string

Luis Calderilla-Barbosa

http://www.w3.org/2001/XMLSchema#string

Maria-Theresa Diaz-Meco

http://www.w3.org/2001/XMLSchema#string

Marie W Wooten

http://www.w3.org/2001/XMLSchema#string

Michael C Wooten

http://www.w3.org/2001/XMLSchema#string

Michael Lamar Seibenhener

http://www.w3.org/2001/XMLSchema#string

P2860

The E3-ubiquitin ligase TRIM50 interacts with HDAC6 and p62, and promotes the sequestration and clearance of ubiquitinated proteins into the aggresome

Regulation of epidermal growth factor receptor trafficking by lysine deacetylase HDAC6

The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase

HDAC6 is a microtubule-associated deacetylase

The deacetylase HDAC6 regulates aggresome formation and cell viability in response to misfolded protein stress

HDAC6 regulates Hsp90 acetylation and chaperone-dependent activation of glucocorticoid receptor

HDAC6 is a specific deacetylase of peroxiredoxins and is involved in redox regulation

Disease-causing mutations in parkin impair mitochondrial ubiquitination, aggregation, and HDAC6-dependent mitophagy

p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy

The protein farnesyltransferase regulates HDAC6 activity in a microtubule-dependent manner

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e76016

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scholarly article

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10.1371/JOURNAL.PONE.0076016

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9

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8

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Jianxiong Jiang

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2013-09-27T00:00:00Z

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257302611

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24086678

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3785417

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