LRRK2 localizes to endosomes and interacts with clathrin-light chains to limit Rac1 activation.
about
G2019S-LRRK2 Expression Augments α-Synuclein Sequestration into Inclusions in Neurons.Clathrin light chains' role in selective endocytosis influences antibody isotype switchingRole and mechanism of action of leucine-rich repeat kinase 1 in bone.Endoplasmic reticulum and lysosomal Ca²⁺ stores are remodelled in GBA1-linked Parkinson disease patient fibroblasts.Alterations in late endocytic trafficking related to the pathobiology of LRRK2-linked Parkinson's disease.Endocytic membrane trafficking and neurodegenerative disease.Rabs, Membrane Dynamics, and Parkinson's Disease.Models of LRRK2-Associated Parkinson's Disease.Leucine-rich repeat kinase-1 regulates osteoclast function by modulating RAC1/Cdc42 Small GTPase phosphorylation and activation.Eiger-induced cell death relies on Rac1-dependent endocytosisThe G2019S LRRK2 mutation increases myeloid cell chemotactic responses and enhances LRRK2 binding to actin-regulatory proteins.Parkinson Sac Domain Mutation in Synaptojanin 1 Impairs Clathrin Uncoating at Synapses and Triggers Dystrophic Changes in Dopaminergic Axons.LRRK2(I2020T) functional genetic interactors that modify eye degeneration and dopaminergic cell loss in Drosophila.Leucine-Rich Repeat Kinase 2 Controls the Ca2+/Nuclear Factor of Activated T Cells/IL-2 Pathway during Aspergillus Non-Canonical Autophagy in Dendritic Cells.Modeling Parkinson's Disease in Drosophila: What Have We Learned for Dominant Traits?
P2860
Q37096048-E847A9A9-3A18-4407-8695-DD029B181121Q37258468-3DD14591-727F-4C78-8CC6-B78B9F78BFACQ37697750-CC130BD3-3408-4F5A-A169-7D81A467F654Q38389995-9A6C6F02-0F69-4A46-A051-5D7CB9A13BDBQ38502057-E1F0F952-4E94-487B-A06E-0405943569F9Q38684233-7B637135-3D1C-43AF-9BD1-3E285024C297Q39031304-3FE33031-2AFA-4997-AF0C-D9527DD2B09EQ39206443-0D53B696-D6CC-43D9-9DA4-909D34EFD6FEQ39417130-48DCB3DF-2C69-455C-8643-829BED9824B9Q40959928-513AE6B3-817D-44B7-AF92-45FD7BE6B447Q41374126-E6044306-389A-435A-85A0-E06E93AC24DBQ46358347-2EC1F96E-5445-4CFA-9C67-5620938FDE6DQ48325551-024D42CE-7A60-4CE4-A8CC-EB353ABAC7B2Q50190181-3D18BF23-F9C1-46CC-B367-7451372FBEA4Q54114687-7B6C3703-A13C-4544-8EA0-E0B167B34AC0
P2860
LRRK2 localizes to endosomes and interacts with clathrin-light chains to limit Rac1 activation.
description
2014 nî lūn-bûn
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2014 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի նոյեմբերին հրատարակված գիտական հոդված
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2014年の論文
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2014年学术文章
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2014年学术文章
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2014年学术文章
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2014年学术文章
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2014年学术文章
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2014年學術文章
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name
LRRK2 localizes to endosomes a ...... ains to limit Rac1 activation.
@ast
LRRK2 localizes to endosomes a ...... ains to limit Rac1 activation.
@en
type
label
LRRK2 localizes to endosomes a ...... ains to limit Rac1 activation.
@ast
LRRK2 localizes to endosomes a ...... ains to limit Rac1 activation.
@en
prefLabel
LRRK2 localizes to endosomes a ...... ains to limit Rac1 activation.
@ast
LRRK2 localizes to endosomes a ...... ains to limit Rac1 activation.
@en
P2093
P2860
P356
P1433
P1476
LRRK2 localizes to endosomes a ...... ains to limit Rac1 activation.
@en
P2093
Andrea M A Schreij
Mathilde Chaineau
Peter S McPherson
Philip A Barker
Wenjing Ruan
P2860
P356
10.15252/EMBR.201438714
P577
2014-11-26T00:00:00Z